Potassium Concentrations in Blood Specimens
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Questions and Answers

What is the main reason for the higher chloride ion concentration in the cerebrospinal fluid (CSF) compared to blood?

  • Increased osmotic pressure in the CSF compared to blood
  • Increased selectivity of the blood-brain barrier against proteins, leading to higher chloride ions to maintain electrical and osmotic equilibrium (correct)
  • Decreased active transport of chloride ions out of the CSF
  • Increased active transport of chloride ions into the CSF
  • What is the primary mechanism responsible for the unequal distribution of ions across the cell membrane?

  • Facilitated diffusion of ions through channel proteins
  • Active transport of sodium out of the cell against an electrochemical gradient (correct)
  • Osmotic pressure differences between the intracellular and extracellular fluids
  • Passive diffusion of ions down their concentration gradients
  • What is the primary function of the Na+/K+-ATPase pump in most cell membranes?

  • To maintain the resting membrane potential (correct)
  • To establish the osmotic gradient between the intracellular and extracellular fluids
  • To transport glucose and other nutrients into the cell
  • To regulate the pH of the intracellular fluid
  • Which of the following is the most significant difference between serum and plasma electrolyte levels?

    <p>Differences in values between serum and heparinized plasma</p> Signup and view all the answers

    What is the primary role of the Na+-H+ exchanger in the cell membrane?

    <p>To regulate the pH of the intracellular fluid</p> Signup and view all the answers

    Which of the following is NOT a typical specimen used for electrolyte analysis?

    <p>Cerebrospinal fluid</p> Signup and view all the answers

    What is the composition of the intracellular fluid (ICF) in terms of total body volume?

    <p>66%</p> Signup and view all the answers

    During bacterial sepsis, what happens to the permeability of the vascular endothelium?

    <p>It increases</p> Signup and view all the answers

    What is the cause of leakage of albumin in pathologic conditions like bacterial sepsis?

    <p>Increased endothelial permeability</p> Signup and view all the answers

    According to Gibbs-Donnan Equilibrium, what happens when two solutions separated by a semipermeable membrane have different concentrations of ions that cannot freely move through?

    <p>Unequal distribution of diffusible ions at steady state occurs</p> Signup and view all the answers

    What is the effect of increased permeability of the vascular endothelium on the effective circulating volume?

    <p>It decreases</p> Signup and view all the answers

    In pathologic conditions like bacterial sepsis, what clinical manifestation is a result of leakage of albumin and reduced effective circulating volume?

    <p>Hypovolemic shock</p> Signup and view all the answers

    Which of the following statements about potassium levels in blood samples is correct?

    <p>Hemolysis of blood can lead to erroneously high potassium results in serum.</p> Signup and view all the answers

    What is the primary role of sodium in the body?

    <p>Maintaining the osmotic pressure in the extracellular fluid compartment.</p> Signup and view all the answers

    What is the recommended daily intake of sodium according to the text?

    <p>3-6 g (90-250 mmol) of sodium per day</p> Signup and view all the answers

    Which of the following processes is NOT mentioned as being of primary importance in the regulation of water balance in the body?

    <p>Regulation of sodium levels by the kidneys</p> Signup and view all the answers

    Which of the following statements about serum and plasma is correct?

    <p>Plasma is preferred for determining blood potassium concentrations due to potential interference from platelets.</p> Signup and view all the answers

    Which of the following statements about proteins in serum is correct?

    <p>The text does not provide any information about the role of proteins in serum.</p> Signup and view all the answers

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