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Questions and Answers
What type of ion channel does a Cl- channel create in the postsynaptic neuron, when activated?
What type of ion channel does a Cl- channel create in the postsynaptic neuron, when activated?
What is the primary characteristic that allows different neuronal responses despite similar basic electrophysiology?
What is the primary characteristic that allows different neuronal responses despite similar basic electrophysiology?
Which factor is least likely to contribute to the regulation and coordination of cellular physiology within a nervous system?
Which factor is least likely to contribute to the regulation and coordination of cellular physiology within a nervous system?
Bioelectricity is defined as what type of activity?
Bioelectricity is defined as what type of activity?
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Which characteristic of neurotransmitters contributes to synaptic transmission diversity?
Which characteristic of neurotransmitters contributes to synaptic transmission diversity?
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What role do intracellular signaling pathways play in neuronal function?
What role do intracellular signaling pathways play in neuronal function?
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What is the primary role of folding in the mammalian nervous system?
What is the primary role of folding in the mammalian nervous system?
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Which statement accurately describes the evolution of brain regions in chordates?
Which statement accurately describes the evolution of brain regions in chordates?
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In terms of functional divisions, how is the vertebrate nervous system structured?
In terms of functional divisions, how is the vertebrate nervous system structured?
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What does the representation of brain processing regions signify in different groups of chordates?
What does the representation of brain processing regions signify in different groups of chordates?
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How does the mammalian brain exemplify complexity in its architecture?
How does the mammalian brain exemplify complexity in its architecture?
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Which statement accurately describes the nervous system organization of sponges?
Which statement accurately describes the nervous system organization of sponges?
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What characterizes cephalization in the evolution of nervous systems?
What characterizes cephalization in the evolution of nervous systems?
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In which group of animals does the presence of a nerve ring indicate a higher level of nervous system organization?
In which group of animals does the presence of a nerve ring indicate a higher level of nervous system organization?
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Which feature is NOT characteristic of arthropod nervous systems?
Which feature is NOT characteristic of arthropod nervous systems?
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Which statement is true about the nervous systems of molluscs compared to arthropods?
Which statement is true about the nervous systems of molluscs compared to arthropods?
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What type of processing is associated with nerve cords found in arthropods?
What type of processing is associated with nerve cords found in arthropods?
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Which of the following statements about echinoderms is correct?
Which of the following statements about echinoderms is correct?
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What distinguishing feature do vertebrates have in regards to their nervous systems?
What distinguishing feature do vertebrates have in regards to their nervous systems?
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What happens when a Na+ channel opens in the post-synaptic neuron?
What happens when a Na+ channel opens in the post-synaptic neuron?
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What is the term used to describe the potential generated in the dendrites of a post-synaptic neuron?
What is the term used to describe the potential generated in the dendrites of a post-synaptic neuron?
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At the axon hillock, the resulting post-synaptic potential can either depolarize or hyperpolarize the membrane. Which factor determines this effect?
At the axon hillock, the resulting post-synaptic potential can either depolarize or hyperpolarize the membrane. Which factor determines this effect?
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What is the effect of K+ ions flowing outward through a K+ channel in a post-synaptic neuron?
What is the effect of K+ ions flowing outward through a K+ channel in a post-synaptic neuron?
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Which statement accurately describes the role of neurotransmitters in post-synaptic electrophysiology?
Which statement accurately describes the role of neurotransmitters in post-synaptic electrophysiology?
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Which of the following correctly describes an electrotonic potential?
Which of the following correctly describes an electrotonic potential?
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What would result from a receptor that allows both Na+ and K+ ions to flow simultaneously?
What would result from a receptor that allows both Na+ and K+ ions to flow simultaneously?
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In the context of post-synaptic potentials, what does the term 'depolarization' refer to?
In the context of post-synaptic potentials, what does the term 'depolarization' refer to?
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What is the primary outcome of the autonomic nervous system's activation?
What is the primary outcome of the autonomic nervous system's activation?
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Which neurotransmitter is primarily associated with the postganglionic fibers of the sympathetic division?
Which neurotransmitter is primarily associated with the postganglionic fibers of the sympathetic division?
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Which of the following correctly describes the relationship between the sympathetic and parasympathetic divisions?
Which of the following correctly describes the relationship between the sympathetic and parasympathetic divisions?
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Which function is primarily activated by the sympathetic nervous system?
Which function is primarily activated by the sympathetic nervous system?
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Identify a key function of the parasympathetic division.
Identify a key function of the parasympathetic division.
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What effect does norepinephrine have on the digestive tract?
What effect does norepinephrine have on the digestive tract?
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What best describes the function of acetylcholine in the autonomic nervous system?
What best describes the function of acetylcholine in the autonomic nervous system?
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Which system is described as the body's 'rest and digest' system?
Which system is described as the body's 'rest and digest' system?
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Which of the following organs would likely be inhibited by sympathetic nervous system activity?
Which of the following organs would likely be inhibited by sympathetic nervous system activity?
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During a 'fight or flight' response, which physiological response is NOT typical?
During a 'fight or flight' response, which physiological response is NOT typical?
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Which statement about the organization of the autonomic nervous system is correct?
Which statement about the organization of the autonomic nervous system is correct?
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What is a characteristic of the sympathetic division?
What is a characteristic of the sympathetic division?
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How do the autonomic divisions maintain homeostasis?
How do the autonomic divisions maintain homeostasis?
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What impact does the parasympathetic division have on heart function?
What impact does the parasympathetic division have on heart function?
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Flashcards
Post-Synaptic Electrophysiology
Post-Synaptic Electrophysiology
Study of electrical changes in neurons after neurotransmitter binding.
Post-Synaptic Potential (PSP)
Post-Synaptic Potential (PSP)
Electrical potential in the post-synaptic neuron after neurotransmitter binding.
Electrotonic Potential (EP)
Electrotonic Potential (EP)
The spread of electrical signal along a neuron's membrane following PSP.
Axon Hillock
Axon Hillock
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Excitatory Post-Synaptic Potential (EPSP)
Excitatory Post-Synaptic Potential (EPSP)
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Ion Channels
Ion Channels
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Depolarization
Depolarization
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Hyperpolarization
Hyperpolarization
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IPSP
IPSP
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Graded Potentials
Graded Potentials
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EPSP
EPSP
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Neurotransmitter Release
Neurotransmitter Release
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Summation of PSPs
Summation of PSPs
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Subthreshold PSPs
Subthreshold PSPs
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Input Integration
Input Integration
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Nervous system evolution
Nervous system evolution
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Conserved brain regions
Conserved brain regions
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Folding increases surface area
Folding increases surface area
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Functional divisions of the brain
Functional divisions of the brain
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Selective pressure
Selective pressure
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Efferent
Efferent
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Autonomic Nervous System (ANS)
Autonomic Nervous System (ANS)
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Somatic Division
Somatic Division
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Sympathetic Division
Sympathetic Division
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Parasympathetic Division
Parasympathetic Division
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Neurotransmitters
Neurotransmitters
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Preganglionic Neuron
Preganglionic Neuron
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Postganglionic Neuron
Postganglionic Neuron
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Antagonistic Effects
Antagonistic Effects
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Tissue-Specific Response
Tissue-Specific Response
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Neurochemistry
Neurochemistry
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Feedback Loops
Feedback Loops
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Homeostasis
Homeostasis
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Innervation
Innervation
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Ganglia
Ganglia
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Sponges
Sponges
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Cephalization
Cephalization
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Nerve Nets
Nerve Nets
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Planarians
Planarians
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Arthropods
Arthropods
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Molluscs
Molluscs
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Vertebrates
Vertebrates
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Synaptic Regulation
Synaptic Regulation
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Bioelectricity
Bioelectricity
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Study Notes
Post-Synaptic Electrophysiology
- Ions move across the post-synaptic membrane due to neurotransmitter binding to receptor
- These cause an electrotonic potential (EP) in dendrites of the post-synaptic neuron
- The EP flows along the membrane surface to the axon hillock
- The EP from the dendrites is called a post-synaptic potential (PSP)
Post Synaptic Potentials
- Channels are proteins within dendrites
- Depend on the type of receptor/ion channel
- A Na+ channel allows Na+ to flow inward, causing a depolarizing or excitatory PSP (EPSP)
- A K+ channel allows K+ to flow outward, causing a hyperpolarizing or inhibitory PSP (IPSP)
- A Cl- channel allows Cl- to flow inward, causing a hyperpolarizing or inhibitory PSP (IPSP)
PSP's are Graded Potentials
- EPSPs and IPSPs are graded potentials (not all or none)
- Graded potentials depend on the amount of neurotransmitter released
- PSP size depends on the strength of stimulus
Postsynaptic Neurons Receive Many Inputs
- Up to 1,000 inputs onto postsynaptic neurons
- These inputs are synaptic connections
Summation of PSPs
- Summation can involve both EPSPs and IPSPs
- Occurs in time and space
- Summation is important for processing inputs, learning, and memory
Overview of Neuronal Signaling Physiology
- Presynaptic neuron releases neurotransmitters
- Postsynaptic neuron receives neurotransmitters
- Action potential occurs, causing synaptic transmission
- Neurotransmitter binding results in a EPSP or IPSP
Post Synaptic Regulation
- All neurons have the same basic electrophysiology
- Postsynaptic regulation differs due to multiple inputs, variety of neurotransmitters, different receptors, and intracellular pathways
- This allows the nervous system to coordinate virtually all cellular physiology
Summary
- Bioelectricity is the electrical activity in living organisms. It's a result of charged particles (ions) moving in and out of cells.
- Nervous systems are designed for optimum functioning.
- The diversity in nervous systems reflects differences in organsim lifestyle and habitat.
Functional Divisions
- Somatic: voluntary control
- Autonomic: involuntary control (sympathetic and parasympathetic)
- Sympathetic: whole body, "fight or flight", organ-specific, "rest and digest"
- Parasympathetic: organ specific, "rest and digest"
The Autonomic Nervous System (ANS)
- Most tissues are innervated by both sympathetic and parasympathetic divisions
- Two efferent neurons and peripheral ganglia are involved
- Integration occurs in ganglia
The ANS Divisions
- Sympathetic: more wide-spread (whole body effects)
- Parasympathetic: more organ-specific effects
Functions of the ANS
- Sympathetic: relaxes airways, increases heartbeat, inhibits digestion, and stimulates heart
- Parasympathetic: constricts airways, slows heartbeat, stimulates digestion, and inhibits heart.
Neurotransmitters & Receptors of The ANS
- Sympathetic: acetylcholine (preganglionic), norepinephrine/adrenoceptors (postganglionic)
- Parasympathetic: acetylcholine (preganglionic), acetylcholine/muscarinic receptors (postganglionic)
ANS Divisions Have Antagonistic Effects
- Sympathetic: more active when body energy stores need to be used ("fight or flight")
- Parasympathetic: more active when body energy stores are being conserved/restored ("rest and digest")
The ANS Activity
- Both divisions are always active, though one is typically more active
- Overall effect depends on which division is more active (sympathetic versus parasympathetic)
ANS Summary
- A major source of integration in the body
- Used to regulate and coordinate the majority of organ systems
- Extensive feedback loops maintain body homeostasis
Pressures on Nervous System Development
- Nervous systems in all animals are designed for optimum functioning.
- Nervous system organization in invertebrates and vertebrates reflects differences in lifestyle and habitat.
- Aquatic vs. terrestrial organisms present different pressures on the development of the nervous system.
Nervous System Evolution in Animals
- Evolution patterns demonstrate a diverse range of nervous system complexity from simple nerve nets in cnidarians to centralized brains in vertebrates.
- Key features like cephalization (concentration of ganglia in a head region) and the emergence of specialized structures (like brain and spinal cord) highlight evolution.
Nervous System Evolution in Chordates
- Brain regions are conserved and modified in different chordate lineages
- Selective pressure influences the relative size and complexity of brain regions to meet the environmental demands of different species.
The Mammalian Nervous System
- Mammalian nervous systems display extreme complexity.
- Brain regions show increasing folding, leading to increased surface area and more synaptic connections.
- This correlates with the more complex behavior/physiology of mammals.
Development of the Human Brain
- Embryonic period of the brain, different regions of the brain develop from different regions of the embryonic brain.
- Regions developed have specific functions in the adult brain.
An Example of Complexity
The mammalian nervous system is divided into functional regions.
Functional Divisions of the Vertebrate Nervous System
- Nervous systems of vertebrates have both central (CNS) and peripheral (PNS) systems
- Input to the CNS and output from the CNS are via afferent and efferent systems, respectively.
- Somatic and autonomic systems constitute the efferent system
- Somatic involves skeletal muscles.
- Autonomic involves smooth muscles, glands, and heart.
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Description
Test your knowledge on post-synaptic electrophysiology with this quiz. Explore the concepts of post-synaptic potentials (PSPs), graded potentials, and the role of ion channels. Understand how neurotransmitters influence neuronal signaling and the implications of excitatory and inhibitory potentials.