Population Genetics and Evolution Concepts
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Questions and Answers

Population genomics examines the amount of genetic variation within ______.

populations

A group of organisms that belong to a particular species living and interbreeding at the same place at a certain time defines a ______.

population

Microevolution involves change within a species or small group over a ______ period of time.

short

Macroevolution refers to major evolutionary change over ______ periods of time.

<p>long</p> Signup and view all the answers

Speciation is the formation of new and ______ species in the course of evolution.

<p>distinct</p> Signup and view all the answers

Gregor Mendel is known for his work in ______ inheritance.

<p>natural</p> Signup and view all the answers

The gene pool includes all of the genetic material including all combinations of genes at a given ______.

<p>time</p> Signup and view all the answers

Charles Darwin is associated with the concept of ______ evolution.

<p>Darwinian</p> Signup and view all the answers

The bottleneck effect is characterized by a sharp reduction in size of a population due to environmental ______ events.

<p>stochastic</p> Signup and view all the answers

The bottleneck effect results in a population restored from a gene pool ______ than before.

<p>smaller</p> Signup and view all the answers

The founder effect occurs when a new population is established from a very ______ number of individuals.

<p>small</p> Signup and view all the answers

Allele frequency can be calculated using the formula ______ + q = 1.

<p>p</p> Signup and view all the answers

Before an environmental event, the allele frequency of B was ______ or 0.45.

<p>9/20</p> Signup and view all the answers

After the environmental event, the proportion of allele B increased to ______ or 0.75.

<p>6/8</p> Signup and view all the answers

The frequency of allele b can be determined by calculating ______ = 1 - p.

<p>q</p> Signup and view all the answers

A larger starting population generally provides more ______ variation than a smaller one.

<p>genetic</p> Signup and view all the answers

The fundamental measurement of allele frequency represents the portion (%) of a gene pool made of a certain ______.

<p>allele</p> Signup and view all the answers

In the context of genetics, phenotype refers to the observable characteristics, while genotype explains the ______ makeup of an organism.

<p>genetic</p> Signup and view all the answers

The Hardy-Weinberg Equation helps in determining the frequency of a particular allele or ______ in a population.

<p>genotype</p> Signup and view all the answers

In the Hardy-Weinberg equation, the expression p2 represents the frequency of the homozygous ______ genotype.

<p>dominant</p> Signup and view all the answers

Genetic equilibrium occurs in populations that meet certain conditions, including no genetic drift and no ______.

<p>mutations</p> Signup and view all the answers

Genetic drift is the change in the frequency of an existing gene allele due to ______ sampling of organisms.

<p>random</p> Signup and view all the answers

The alleles B and b denote dominant and ______ alleles, respectively.

<p>recessive</p> Signup and view all the answers

The equation p + q = 1 helps to determine the frequency of dominant (p) and ______ (q) alleles in a population.

<p>recessive</p> Signup and view all the answers

The new population can become genetically distinct both phenotypically and ______ from the original population.

<p>genotypically</p> Signup and view all the answers

Extreme cases can lead to ______ and the subsequent evolution of new species.

<p>speciation</p> Signup and view all the answers

Gene Flow involves the movement of genetic variation from one population to ______.

<p>another</p> Signup and view all the answers

Non-random mating occurs with individuals who have a closer ______.

<p>relationship</p> Signup and view all the answers

Random Mating mixes the genes in the gene pool for the next generation, while Non-random Mating favours some genes and traits over ______.

<p>others</p> Signup and view all the answers

Natural Selection is often described as the survival of the ______.

<p>fittest</p> Signup and view all the answers

The ______ Effect can cause a new population to be genetically distinct from its source population.

<p>Founder</p> Signup and view all the answers

Stabilizing selection favors individuals with ______ phenotypes.

<p>average</p> Signup and view all the answers

Directional selection occurs when individuals with traits on one side of the ______ survive better.

<p>mean</p> Signup and view all the answers

After migration, the allele frequency in Population 1 changes from B or p = 10/10 to ______ = 0.83.

<p>10/12</p> Signup and view all the answers

The equation for allele frequency is p + q = ______.

<p>1</p> Signup and view all the answers

Disruptive selection favors individuals with traits on ______ sides of the mean.

<p>both</p> Signup and view all the answers

An example of stabilizing selection can be observed in ______ weight.

<p>human birth</p> Signup and view all the answers

The environment selects against individuals with extreme ______.

<p>phenotypes</p> Signup and view all the answers

An example of directional selection is the length of a giraffe's ______.

<p>neck</p> Signup and view all the answers

Genetic variations are crucial for ______ to occur among organisms.

<p>evolution</p> Signup and view all the answers

Population genomics is concerned with the hereditary makeup of ______.

<p>populations</p> Signup and view all the answers

The concept of ______ evolution involves a gradual change within a species over time.

<p>micro</p> Signup and view all the answers

Natural selection can lead to the evolution of new ______ through speciation.

<p>species</p> Signup and view all the answers

In terms of genetics, the gene pool represents all the ______ material in a given population.

<p>genetic</p> Signup and view all the answers

The ______ effect occurs when a new population is started by a small group from a larger population.

<p>founder</p> Signup and view all the answers

The term ______ selection describes a scenario where individuals with extreme traits are selected against.

<p>stabilizing</p> Signup and view all the answers

Directional selection occurs when individuals with certain ______ traits have a survival advantage.

<p>traits</p> Signup and view all the answers

Gene flow is the transfer of genetic ______ from one population to another.

<p>material</p> Signup and view all the answers

The portion (%) of a gene pool made of a certain ______ is known as allele frequency.

<p>allele</p> Signup and view all the answers

In the Hardy-Weinberg equation, the expression 2pq represents the frequency of the ______ genotype.

<p>heterozygous</p> Signup and view all the answers

Genetic equilibrium pertains to genetics of non-______ populations.

<p>evolving</p> Signup and view all the answers

A change in the frequency of an existing gene allele due to random sampling of organisms is referred to as ______ drift.

<p>genetic</p> Signup and view all the answers

An equation used for determining the frequency of a particular allele or genotype in a population is called the ______-Weinberg equation.

<p>Hardy</p> Signup and view all the answers

In genetics, individuals that have the same alleles are referred to as ______.

<p>homozygous</p> Signup and view all the answers

The conditions for genetic equilibrium are virtually ______ met in natural populations.

<p>never</p> Signup and view all the answers

The letter 'p' in the Hardy-Weinberg equation usually represents the frequency of the ______ allele.

<p>dominant</p> Signup and view all the answers

The ______ effect occurs when a new population is established from a very small number of individuals.

<p>founder</p> Signup and view all the answers

The ______ effect consists of a sharp reduction in size of a population due to environmental stochastic events.

<p>bottleneck</p> Signup and view all the answers

A new population established through the founder effect often exhibits a lack of ______ variation.

<p>genetic</p> Signup and view all the answers

Environmental events can lead to a rapid ______ in population size, impacting allele frequency.

<p>decline</p> Signup and view all the answers

After a bottleneck event, the population is restored from a gene pool ______ than before.

<p>smaller</p> Signup and view all the answers

In allele frequency calculations, p + q = ______.

<p>1</p> Signup and view all the answers

The process of gene migration involves the movement of genetic variation from one population to ______.

<p>another</p> Signup and view all the answers

Before an environmental event, the allele frequency of B was calculated to be ______.

<p>0.45</p> Signup and view all the answers

Non-random mating causes a non-random distribution of ______ in an individual.

<p>alleles</p> Signup and view all the answers

Genetic drift occurs due to ______ sampling of organisms, affecting allele frequencies over time.

<p>random</p> Signup and view all the answers

The founder effect occurs when a new population is established from a very small number of ______.

<p>individuals</p> Signup and view all the answers

The equation for allele frequency is ______ + q = 1.

<p>p</p> Signup and view all the answers

Extreme cases of genetic divergence can lead to ______, resulting in the evolution of new species.

<p>speciation</p> Signup and view all the answers

After migration, the allele frequency in a population can change, illustrating the effects of gene ______.

<p>flow</p> Signup and view all the answers

Mutations are a source of new genetic ______ in a population.

<p>variation</p> Signup and view all the answers

Natural selection is a mechanism of ______.

<p>evolution</p> Signup and view all the answers

Stabilizing selection drives down population genetic ______.

<p>diversity</p> Signup and view all the answers

Directional selection favors individuals with traits on one ______ of the mean in their population.

<p>side</p> Signup and view all the answers

Disruptive selection favors individuals with traits on both _____ of the mean.

<p>sides</p> Signup and view all the answers

An example of stabilizing selection can be observed in human birth ______.

<p>weight</p> Signup and view all the answers

The rarest among the different selection types is ______ selection.

<p>disruptive</p> Signup and view all the answers

The fur color of rock pocket mice is an example of ______ selection.

<p>disruptive</p> Signup and view all the answers

Directional selection can be observed in the neck length of a ______.

<p>giraffe</p> Signup and view all the answers

Which statement correctly defines microevolution?

<p>Minor genetic changes within populations over short timescales.</p> Signup and view all the answers

What is meant by the term gene pool?

<p>All genetic combinations present in a population at a given time.</p> Signup and view all the answers

Which process is described as branching phylogeny?

<p>The formation of new species from an ancestral lineage.</p> Signup and view all the answers

Which statement accurately represents the concept of gene flow?

<p>The movement of genetic material due to migration between populations.</p> Signup and view all the answers

What is the primary focus of population genomics?

<p>Investigating hereditary variation and its influences within populations.</p> Signup and view all the answers

Which of the following best describes stabilizing selection?

<p>Natural selection reducing variation and favoring intermediate traits.</p> Signup and view all the answers

What distinguishes macroevolution from microevolution?

<p>Macroevolution involves significant changes over long timescales, resulting in new species.</p> Signup and view all the answers

Which concept does Darwin's theory of evolution best illustrate?

<p>Branching phylogeny explaining the common ancestry of species.</p> Signup and view all the answers

What is the main consequence of the Founder Effect in population genetics?

<p>Genetic distinctness from the original population</p> Signup and view all the answers

In gene flow, what happens to allele frequencies after migration?

<p>They can increase or decrease depending on the source</p> Signup and view all the answers

How does non-random mating affect allele distribution?

<p>It results in a non-random distribution of alleles</p> Signup and view all the answers

Which of the following statements is true regarding mutations?

<p>Mutations can introduce new genetic variations</p> Signup and view all the answers

Which combination of allele frequencies indicate a genetic equilibrium?

<p>p = 0.5 and q = 0.5</p> Signup and view all the answers

Which process describes the movement of genetic variation from one population to another?

<p>Gene flow</p> Signup and view all the answers

What does the Hardy-Weinberg equation assess?

<p>The frequencies of alleles in a population at equilibrium</p> Signup and view all the answers

Which of the following correctly defines random mating?

<p>Mating among individuals with varied traits</p> Signup and view all the answers

What characterizes the bottleneck effect in a population's gene pool?

<p>A sharp reduction in population size due to environmental events</p> Signup and view all the answers

What is the outcome of the founder effect on genetic variation?

<p>A lack of genetic variation in the new population</p> Signup and view all the answers

How is allele frequency calculated within a population?

<p>Using the formula $p + q = 1$</p> Signup and view all the answers

What happens to the allele frequency after a population experiences a bottleneck event?

<p>Allele frequencies may shift significantly towards dominance</p> Signup and view all the answers

In terms of environmental impacts, what typically leads to the bottleneck effect?

<p>Environmental changes or catastrophic events</p> Signup and view all the answers

Which statement correctly describes the allele frequency before and after a bottleneck event?

<p>The frequency of dominant alleles may become more prevalent</p> Signup and view all the answers

What is a likely characteristic of a population affected by the founder effect?

<p>A limited genetic variation due to a small founding group</p> Signup and view all the answers

What could be a consequence of a severe bottleneck event on a population's future?

<p>A higher likelihood of extinction due to reduced genetic diversity</p> Signup and view all the answers

Which condition is NOT required for genetic equilibrium according to the Hardy-Weinberg principle?

<p>Small population size</p> Signup and view all the answers

In the Hardy-Weinberg equation, what does the term $2pq$ represent?

<p>Frequency of heterozygous genotype</p> Signup and view all the answers

What is the effect of genetic drift on allele frequency in small populations?

<p>It randomly changes allele frequencies.</p> Signup and view all the answers

Which statement accurately describes allele frequency?

<p>It is the portion of a gene pool made of a specific allele.</p> Signup and view all the answers

What does the Hardy-Weinberg equation primarily help determine?

<p>The frequency of specific alleles or genotypes in a population</p> Signup and view all the answers

Genetic equilibrium does not occur when which of the following conditions is present?

<p>Small population size</p> Signup and view all the answers

What is the significance of the symbols $p$ and $q$ in the Hardy-Weinberg equation?

<p>They denote the respective frequencies of two alleles in a population.</p> Signup and view all the answers

Which scenario best exemplifies genetic drift?

<p>A small group forming a new population from a larger one.</p> Signup and view all the answers

What type of selection favors individuals with traits on both sides of the mean?

<p>Disruptive selection</p> Signup and view all the answers

Which type of selection drives down population genetic diversity by favoring average individuals?

<p>Stabilizing selection</p> Signup and view all the answers

In directional selection, which of the following traits is favored?

<p>Traits on one side of the mean</p> Signup and view all the answers

An example of stabilizing selection is related to which of the following?

<p>Bird egg clutch number</p> Signup and view all the answers

Which type of selection is least likely to lead to speciation?

<p>Stabilizing selection</p> Signup and view all the answers

Which selection type can lead to greater adaptation by selecting against intermediate phenotypes?

<p>Disruptive selection</p> Signup and view all the answers

Which of the following is an example of directional selection?

<p>Increased neck length in giraffes</p> Signup and view all the answers

Natural selection is often summarized by which phrase?

<p>Survival of the fittest</p> Signup and view all the answers

Which statement best describes microevolution?

<p>It refers to evolutionary changes that affect a population over a short span.</p> Signup and view all the answers

What is the correct definition of speciation in evolutionary biology?

<p>The emergence of new species from an ancestral lineage over evolutionary time.</p> Signup and view all the answers

Which concept has been discredited concerning the evolution of organisms?

<p>Orthogenesis as an innate driving force for evolution</p> Signup and view all the answers

In the context of genetic variation, what does the gene pool represent?

<p>All genetic material and combinations of genes within a population at a specific time</p> Signup and view all the answers

What does genetic drift primarily result from?

<p>Random sampling effects that influence allele frequencies in a population</p> Signup and view all the answers

What is an example of stabilizing selection?

<p>Birds with moderate beak sizes having higher survival rates</p> Signup and view all the answers

Directional selection is characterized by which of the following?

<p>Survival of individuals with traits on one side of the mean</p> Signup and view all the answers

How does gene flow impact allele frequencies in a population?

<p>It can introduce or remove alleles, altering allele frequencies.</p> Signup and view all the answers

What is a consequence of non-random mating in a population?

<p>Favoring certain traits may lead to a reduction in allele variation.</p> Signup and view all the answers

Which phenomenon is likely to lead to speciation the quickest?

<p>The founder effect causing isolation of a small group.</p> Signup and view all the answers

How does a mutation contribute to genetic diversity in populations?

<p>It creates new alleles, providing raw material for evolution.</p> Signup and view all the answers

Which statement best describes the relationship between allele frequency and genetic equilibrium?

<p>Genetic equilibrium results from constant allele frequencies over generations.</p> Signup and view all the answers

What best illustrates the founder effect?

<p>A small group from a diverse population forms a new population in isolation.</p> Signup and view all the answers

In the context of genetic variation, what is one result of gene migration?

<p>It can homogenize allele frequencies among different populations.</p> Signup and view all the answers

What impact does the Hardy-Weinberg equilibrium have on allele stability in a population?

<p>It prevents allele frequencies from changing unless external pressures are applied.</p> Signup and view all the answers

What characterizes the bottleneck effect?

<p>A sharp reduction in population size due to environmental events.</p> Signup and view all the answers

Which statement best describes the founder effect?

<p>It is caused by the establishment of a population from a small number of individuals.</p> Signup and view all the answers

After a population experiences a bottleneck effect, what typically happens to the allele frequencies?

<p>Allele frequencies may increase for certain alleles.</p> Signup and view all the answers

In the context of allele frequency, what does the equation p + q = 1 represent?

<p>The relationship between dominant and recessive alleles in a population.</p> Signup and view all the answers

What is a common consequence of the founder effect?

<p>Homogeneity of the population regarding certain traits.</p> Signup and view all the answers

How does allele frequency typically change after a severe environmental event for a small population?

<p>Certain alleles may become more prevalent by chance.</p> Signup and view all the answers

What can be an effect of a bottleneck on the genetic structure of a population?

<p>Increased susceptibility to environmental changes.</p> Signup and view all the answers

In what manner does a larger starting population affect genetic variation when compared to a smaller one?

<p>It often results in greater genetic diversity.</p> Signup and view all the answers

What does stabilizing selection primarily favor within a population?

<p>Intermediate or average phenotypes</p> Signup and view all the answers

Which type of selection would likely lead to the evolution of new species?

<p>Disruptive selection</p> Signup and view all the answers

In directional selection, which of the following statements is true?

<p>One extreme phenotype is favored over others.</p> Signup and view all the answers

What effect does stabilizing selection have on genetic variation?

<p>Drives down the population genetic diversity.</p> Signup and view all the answers

An example of which type of selection can be seen in the fur color of rock pocket mice?

<p>Disruptive selection</p> Signup and view all the answers

In the context of natural selection, what is most likely to happen to individuals with extreme phenotypes?

<p>They will be selected against and have lower survival rates.</p> Signup and view all the answers

What characteristic of directional selection is highlighted in the evolution of the peppered moth?

<p>It favors one extreme phenotype due to environmental changes.</p> Signup and view all the answers

Which of the following statements correctly describes disruptive selection?

<p>It has the potential to create two distinct populations.</p> Signup and view all the answers

What does the Hardy-Weinberg equation specifically help to determine?

<p>The frequency of a particular allele or genotype in a population</p> Signup and view all the answers

Which condition is NOT required for a population to achieve genetic equilibrium?

<p>Presence of mutations</p> Signup and view all the answers

What does the term 'genetic drift' refer to in population genetics?

<p>The random fluctuation in allele frequencies due to chance events</p> Signup and view all the answers

In the Hardy-Weinberg equation, what does the 'p2' term represent?

<p>Frequency of homozygous dominant genotypes</p> Signup and view all the answers

Which of the following statements is true about allele frequency?

<p>It denotes the proportion of a specific allele within the gene pool</p> Signup and view all the answers

Which factor is a consequence of genetic flow between populations?

<p>Enhanced adaptation of populations to their environments</p> Signup and view all the answers

Which of the following conditions would likely disrupt the Hardy-Weinberg equilibrium?

<p>Selective mating preferences</p> Signup and view all the answers

What is the role of the 'q' variable in the Hardy-Weinberg equation?

<p>It corresponds to the frequency of a recessive allele in the population</p> Signup and view all the answers

What does microevolution primarily involve?

<p>Change within a species over short time frames</p> Signup and view all the answers

Which statement best describes speciation?

<p>Formation of new and distinct species</p> Signup and view all the answers

What is the main characteristic of macroevolution?

<p>Major evolutionary changes over long periods</p> Signup and view all the answers

Which of the following hypotheses has been discredited?

<p>Orthogenesis</p> Signup and view all the answers

What is genetic drift primarily driven by?

<p>Random sampling of organisms</p> Signup and view all the answers

What represents the total genetic variation in a population at a given time?

<p>Gene pool</p> Signup and view all the answers

Which factor does NOT contribute to changes in allele frequency within populations?

<p>Phenotypic expression</p> Signup and view all the answers

What does the Hardy-Weinberg Equation help determine?

<p>Allele frequency in a population</p> Signup and view all the answers

What condition is NOT required for a population to be in genetic equilibrium?

<p>Presence of mutations</p> Signup and view all the answers

Which of the following best describes genetic drift?

<p>Random changes in allele frequencies due to sampling error</p> Signup and view all the answers

In the context of the Hardy-Weinberg equation, what does 'p' represent?

<p>Frequency of the dominant allele</p> Signup and view all the answers

Which term describes the observable characteristics of an organism?

<p>Phenotype</p> Signup and view all the answers

What is the significance of the expression '2pq' in the Hardy-Weinberg equation?

<p>Frequency of heterozygous genotype</p> Signup and view all the answers

Which condition is indicative of genetic equilibrium?

<p>Large population size</p> Signup and view all the answers

What does 'q' represent in the allele frequency equation 'p + q = 1'?

<p>Frequency of a recessive allele</p> Signup and view all the answers

What type of selection favors individuals with extreme traits on both sides of the phenotypic spectrum?

<p>Disruptive selection</p> Signup and view all the answers

Which of the following is an example of stabilizing selection?

<p>Bird egg clutch number</p> Signup and view all the answers

In directional selection, which phenotypes are favored?

<p>Individuals with traits on one side of the mean</p> Signup and view all the answers

What is the main effect of stabilizing selection on genetic diversity?

<p>Drives down population genetic diversity</p> Signup and view all the answers

Which selection type is most likely to lead to speciation?

<p>Disruptive selection</p> Signup and view all the answers

What is the primary mechanism of evolution known as the 'survival of the fittest'?

<p>Natural selection</p> Signup and view all the answers

Which of the following is an example of disruptive selection?

<p>Fur color of rock pocket mice</p> Signup and view all the answers

In what scenario is stabilizing selection most likely to occur?

<p>When the average phenotypes are most successful</p> Signup and view all the answers

What can extreme cases of genetic distinction lead to?

<p>Speciation</p> Signup and view all the answers

Which of the following accurately describes gene flow?

<p>The migration of genetic variation between populations</p> Signup and view all the answers

What mathematical expression represents the sum of allele frequencies in a population?

<p>p + q = 1</p> Signup and view all the answers

What effect does the founder effect have on a new population?

<p>It usually causes genetic uniformity</p> Signup and view all the answers

In the context of mating, what does non-random mating imply?

<p>Individuals select mates based on genetic similarity</p> Signup and view all the answers

Which aspect is NOT affected by genetic mutations?

<p>Mating patterns</p> Signup and view all the answers

What is one direct consequence of selective non-random mating?

<p>Altered gene frequencies over generations</p> Signup and view all the answers

What characterizes the bottleneck effect in a population?

<p>A sharp reduction in population size due to environmental events</p> Signup and view all the answers

What is the primary consequence of the founder effect?

<p>Loss of genetic variation</p> Signup and view all the answers

How does the allele frequency change after a bottleneck event?

<p>It may show significant shifts due to the smaller gene pool</p> Signup and view all the answers

What is represented by the equation p + q = 1?

<p>The relationship between allele frequencies in a population</p> Signup and view all the answers

If allele B has a frequency p = 0.45, what is the frequency of allele b?

<p>0.55</p> Signup and view all the answers

Which situation describes a case of the founder effect?

<p>A small group of individuals establishes a new population in a different location</p> Signup and view all the answers

What effect can a larger starting population have on genetic variation?

<p>It generally provides more genetic variation</p> Signup and view all the answers

What does the bottleneck effect imply about the restored population?

<p>It will have a smaller gene pool compared to the original population</p> Signup and view all the answers

Study Notes

Population Genomics

  • Population genomics is a branch of genomics that examines variations in the genetic makeup of populations.
  • It identifies the amount of genetic variation within populations and factors influencing that variation.

Defining a Population

  • Genetic Definition: A group of organisms belonging to the same species, living in the same place, and interbreeding at a specific time.
  • Statistical/Mathematical Definition: A group of organisms identifiable by shared characteristics used for data collection and analysis.

Dominant and Recessive Inheritance

  • Gregor Mendel's work forms the basis of understanding dominant and recessive inheritance.
  • Dominant traits are expressed even when only one copy of the relevant gene is present.
  • Recessive traits only appear when both copies of the gene are present.

Natural Selection

  • Natural selection is an evolutionary mechanism.
  • It favors organisms better adapted to their environment, and these organisms are more likely to multiply.
  • Gene changes that enhance survival increase in frequency over time.

Evolution of Evolution

  • Orthogenesis: An outdated theory suggesting living things have a predetermined evolutionary pathway.
  • Branching Phylogeny/Cladogenesis: The most contemporary evolutionary theory, suggesting species branch off from common ancestors.

Micro and Macroevolution

  • Microevolution: Evolutionary change within a species or a small group of organisms over a short period.
  • Macroevolution: Significant evolutionary changes across a long period, leading to the formation of new species.
  • Speciation: The process of new species formation.

Gene Pool

  • The gene pool contains all genetic material (genes and their combinations) within a species or population at a particular time.
  • Allele Frequency: The portion (%) of the gene pool made up of a particular allele.

Genetic Terminology

  • Phenotype: Observable traits (e.g., blue fur).
  • Alleles: Different forms of a gene (e.g., B and b).
    • Dominant allele (e.g., B)
    • Recessive allele (e.g., b)
  • Genotype: The genetic makeup of an individual (e.g., BB, Bb, or bb).

Hardy Weinberg Equation

  • p + q = 1 (Sum of dominant (p) and recessive (q) allele frequencies = 1)
  • p² + 2pq + q² = 1 (Sums of homozygous dominant (p²), heterozygous (2pq), and homozygous recessive (q²) genotype frequencies = 1)
  • It is used to determine allele and genotype frequencies in a population.

Genetic Equilibrium

  • Describes populations with stable allele and genotype frequencies.
  • Specific conditions must exist for equilibrium to remain:
    • No genetic drift

    • No gene flow/migration

    • Random mating

    • No mutations
    • No natural selection

    • Extremely large population size
  • These conditions (rarely) occur naturally.

Genetic Drift

  • Genetic drift refers to a random fluctuation in the frequency of genes or alleles, especially in small populations.
  • It leads to evolutionary changes.
  • Common types of genetic drift:  
    • Founder effect
    • Bottleneck effect

Founder Effect

  • Formation of a new population from a small group of individuals originating from the original population.
  • The new population demonstrates reduced genetic variation compared to the original population.

Bottleneck Effect

  • A significant reduction in a population's size due to environmental factors, leading to a reduced gene pool.
  • The reduced gene pool can affect the population's future evolution and potentially lead to extinction.

Gene Flow (Migration)

  • The movement of genetic variation between populations.
  • It can introduce new alleles into a population, or remove alleles.

Non-Random Mating

  • Individuals choose mates based on traits, rather than randomly.
  • This results in non-random allele distribution in a population.

Mutations

  • Mutations are changes in the DNA sequence. These changes can be caused by errors during DNA replication, exposure to mutagens, or other factors.
  • Mutations introduce new alleles and variety into a population.
  • Mutation types include:
    • Point mutations (substitutions)

    • Insertion/deletion mutations (Indels)

Natural Selection

  • Natural selection (survival of the fittest) favors traits that improve survival and reproduction in a given environment.

  • Differential survival and reproduction result in a shift in gene frequencies over time.

  • Types of natural selection include:

    • Stabilizing selection (favors the average phenotype)

    • Directional selection (favors one extreme phenotype)

    • Disruptive selection (favors both extreme phenotypes)

What Causes Variation

  • Random mating: Diverse mate combinations create varied combinations of alleles.
  • Random fertilization & recombination during meiosis lead to new allele combinations.
  • Mutations: Changes in DNA sequence introduce new alleles.

Altering Genetic Equilibrium:

  • A change in genetic equilibrium leads to evolution in a population.
  • The Hardy–Weinberg principle is used as a baseline to compare or understand gene pools in actual populations.

Real-World Population Implications

  • Populations display differences in genetic composition due to evolution and other factors.
  • Factors influencing human populations include skill specialization, consanguinity (mating between related individuals), and disease transmission.

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This quiz explores key concepts in population genomics and evolution, focusing on genetic variation, speciation, and the effects of historical events on populations. It features crucial terms and principles introduced by figures such as Gregor Mendel and Charles Darwin.

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