Population Distribution in Pharmacology

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Questions and Answers

What is the value of X in the given equation, where V.Z = X - µ/σ?

  • 78.18
  • 80.58
  • 77.58
  • 78.58 (correct)

What is the primary purpose of calculating the Z-value?

  • To determine the mode of a dataset
  • To determine the standard deviation of a dataset
  • To determine the mean of a dataset
  • To determine the probability of occurrence of an event (correct)

What is the shape of the distribution curve when the data is skewed to the left?

  • Asymmetrical with a longer left tail (correct)
  • Asymmetrical with a longer right tail
  • Symmetrical
  • Bimodal

What is the difference between the normal distribution curve and the t-distribution curve?

<p>The normal distribution curve doesn't represent the sample number (C)</p> Signup and view all the answers

What is the formula to calculate the t-value?

<p>[X - µ] / SE (A)</p> Signup and view all the answers

What is the area of the curve that is above 130 mmHg in a normal distribution curve with µ = 120 and σ = 10?

<p>P = 0.0228 (D)</p> Signup and view all the answers

What is the importance of the Z-value in a normal distribution curve?

<p>To determine the probability of occurrence of an event (A)</p> Signup and view all the answers

What is the shape of the distribution curve when the data is skewed to the right?

<p>Asymmetrical with a longer right tail (D)</p> Signup and view all the answers

What is the value of the systolic blood pressure that divides the area under the curve into lower 97.5% and upper 2.5%?

<p>138.58 mmHg (D)</p> Signup and view all the answers

What is the primary difference between the normal distribution curve and the t-distribution curve?

<p>The sample size used to estimate the population mean (D)</p> Signup and view all the answers

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Study Notes

Population Distribution

  • Population distribution can be discrete, skewed, or normal (also known as continuous or Gaussian).
  • Normal frequency distribution (NFD) is a continuous probability distribution with values ranging from -∞ to +∞.
  • Each NFD is defined by its mean (µ) and standard deviation (σ).

Characteristics of Normal Frequency Distribution (NFD)

  • Bell-shaped curve
  • Symmetric
  • Mean = mode = median
  • The area under the curve represents all probabilities
  • Data are clustered around the mean
  • The distribution of data around the mean µ is described by units of standard deviation σ

Standard Normal Frequency Distribution (Z Distribution)

  • Hypothetical curve where µ = 0 and σ = 1
  • Z value is the fraction of standard deviation on the scale
  • Z values range from -3 to +3
  • The area represents the probability of occurrence of an event, and total area = 1 (represents 100%)

Importance of Z Value

  • Decides whether an observation is normal or not
  • Determines the probability of occurrence of an event in NFD curve
  • Examples of determining probabilities using Z values are provided

Skewed Distribution

  • Not symmetrical
  • Can be negatively skewed (pulled to the left) or positively skewed (pulled to the right)

The t-Distribution

  • Used to describe the distribution of means around the universal mean when the SD is unknown, but an estimate is available from a relatively small sample number
  • For each sample size, there will be a special t-distribution curve
  • t value = [𝑋 - µ] / SE
  • Differences between NFD curve and t-distribution are:
    • NFD doesn’t represent the sample number
    • NFD is steep, while t-distribution is less steep and becomes less steep as n decreases

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