Podcast
Questions and Answers
What is the primary purpose of prescription medication for older patients?
What is the primary purpose of prescription medication for older patients?
What is the increased likelihood of frailty for patients taking five or more medications?
What is the increased likelihood of frailty for patients taking five or more medications?
What is the increased likelihood of being prescribed an inappropriate medication for frail patients?
What is the increased likelihood of being prescribed an inappropriate medication for frail patients?
What are the frailty syndromes that medications can cause or contribute to?
What are the frailty syndromes that medications can cause or contribute to?
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Which of the 5Ms is most relevant to polypharmacy?
Which of the 5Ms is most relevant to polypharmacy?
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What is a major difficulty associated with polypharmacy?
What is a major difficulty associated with polypharmacy?
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What type of research studies are commonly used in the field of polypharmacy?
What type of research studies are commonly used in the field of polypharmacy?
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What is the purpose of identifying the strength of an association between an illness and a specific medication?
What is the purpose of identifying the strength of an association between an illness and a specific medication?
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What is the primary consequence of polypharmacy on patients' quality of life?
What is the primary consequence of polypharmacy on patients' quality of life?
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What is the primary challenge in establishing a causal relationship between medication use and patient outcomes?
What is the primary challenge in establishing a causal relationship between medication use and patient outcomes?
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What is the primary focus of the 'Matters most' aspect of the 5Ms?
What is the primary focus of the 'Matters most' aspect of the 5Ms?
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What is the primary advantage of observational studies in the field of polypharmacy?
What is the primary advantage of observational studies in the field of polypharmacy?
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What is the primary consequence of polypharmacy on the caregiver or family member?
What is the primary consequence of polypharmacy on the caregiver or family member?
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What is the primary challenge in deprescribing for patients with multi-complexity?
What is the primary challenge in deprescribing for patients with multi-complexity?
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What is the primary goal of the 'Mind' aspect of the 5Ms?
What is the primary goal of the 'Mind' aspect of the 5Ms?
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What is the primary advantage of the 5Ms framework in the context of polypharmacy?
What is the primary advantage of the 5Ms framework in the context of polypharmacy?
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Study Notes
The Impact of Polypharmacy
- Older patients taking five or more medications are 1.5 times more likely to become frail within a 3-year period than those who take less than five medications.
- Frail patients are twice as likely to be prescribed an inappropriate medication than patients who are not experiencing frailty.
- Polypharmacy can negatively impact patients and their families or carers.
- Frailty syndromes include falls, cognitive impairment, incontinence, immobility, and susceptibility to side-effects of medications.
- Medications can cause or contribute to all of these syndromes.
The 5Ms
- The 5Ms principles and actions are relevant to deprescribing.
- Mind: Mentation, dementia, delirium, depression.
- Mobility: Impaired gait and balance, fall injury prevention.
- Medications: Polypharmacy, deprescribing, adverse medication effects, medication burden.
- Multi-complexity: Multi-morbidity, complex bio-psychosocial situations.
- Matters most: Each patient has meaningful health outcome goals and care preferences.
Polypharmacy Research
- Determining cause and effect is difficult in polypharmacy research.
- Authors rely on identifying the strength of an association between an illness and a specific medication.
- Observational studies (e.g., cohorts) are typically used in polypharmacy research.
- Experimental studies are often unfeasible in this field.
- Observational research has identified risk factors for older persons taking multiple medications.
The Impact of Polypharmacy
- Older patients taking five or more medications are 1.5 times more likely to become frail within a 3-year period than those who take less than five medications.
- Frail patients are twice as likely to be prescribed an inappropriate medication than patients who are not experiencing frailty.
- Polypharmacy can negatively impact patients and their families or carers.
- Frailty syndromes include falls, cognitive impairment, incontinence, immobility, and susceptibility to side-effects of medications.
- Medications can cause or contribute to all of these syndromes.
The 5Ms
- The 5Ms principles and actions are relevant to deprescribing.
- Mind: Mentation, dementia, delirium, depression.
- Mobility: Impaired gait and balance, fall injury prevention.
- Medications: Polypharmacy, deprescribing, adverse medication effects, medication burden.
- Multi-complexity: Multi-morbidity, complex bio-psychosocial situations.
- Matters most: Each patient has meaningful health outcome goals and care preferences.
Polypharmacy Research
- Determining cause and effect is difficult in polypharmacy research.
- Authors rely on identifying the strength of an association between an illness and a specific medication.
- Observational studies (e.g., cohorts) are typically used in polypharmacy research.
- Experimental studies are often unfeasible in this field.
- Observational research has identified risk factors for older persons taking multiple medications.
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Description
Learn about the impact of polypharmacy on older adults, including the risk of frailty and inappropriate medication. Understand the effects of taking five or more medications on quality of life.
