Polycystic Kidney Disease (PKD)
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Questions and Answers

What percentage of dialysis patients have Polycystic Kidney Disease?

  • 10 to 12%
  • 3 to 5%
  • 6 to 8% (correct)
  • 15 to 18%

What is the effect of the defect in polycystin-1 or polycystin-2 in Polycystic Kidney Disease?

  • No effect on kidney function
  • Reduced fluid retention and smaller cysts
  • Increased kidney function
  • Fluid retention and cyst formation (correct)

What is a risk factor for Chronic Renal Failure?

  • Family history (correct)
  • Age < 40 years
  • Race other than African American
  • Lack of atherosclerosis

What is the percentage of normal GFR associated with End-Stage Renal Failure?

<p>10% or less (A)</p> Signup and view all the answers

Why do symptoms of renal failure not appear until 75% or greater of renal function is lost?

<p>The kidneys have a large reserve capacity (C)</p> Signup and view all the answers

What is the term for a decline in GFR to about 25% of normal?

<p>Renal Insufficiency (C)</p> Signup and view all the answers

What is the term for kidney damage caused by a marked decrease in renal blood flow?

<p>Prerenal (C)</p> Signup and view all the answers

Which of the following is NOT a risk factor for acute renal dysfunction?

<p>Regular Exercise (C)</p> Signup and view all the answers

What is the main product of protein breakdown in the diet?

<p>Urea nitrogen (BUN) (A)</p> Signup and view all the answers

What is the term for kidney damage caused by obstruction of urine outflow from the kidney?

<p>Postrenal (D)</p> Signup and view all the answers

What percentage of patients with acute renal dysfunction have more than one risk factor?

<p>62% (B)</p> Signup and view all the answers

What is a possible indicator of kidney function?

<p>Creatinine level in the blood (C)</p> Signup and view all the answers

What is a possible cause of prerenal dysfunction?

<p>Hypotension (D)</p> Signup and view all the answers

What is a possible consequence of oliguria?

<p>Ischemia to the kidney (C)</p> Signup and view all the answers

What is a possible cause of postrenal dysfunction?

<p>Prostate enlargement (D)</p> Signup and view all the answers

What is a possible effect of uncontrolled diabetes on kidney disease?

<p>It accelerates kidney disease (A)</p> Signup and view all the answers

What is a possible consequence of hydronephrosis?

<p>Toxicity to nephron cells (B)</p> Signup and view all the answers

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