Pleural Effusion and Its Causes
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Questions and Answers

What is the minimum amount of pleural fluid accumulation that typically leads to visible findings?

  • 400 ml
  • 300 ml
  • 200 ml (correct)
  • 100 ml

What characteristic is commonly observed in the imaging of pleural effusion?

  • Homogeneous density with a meniscus-shaped margin (correct)
  • Bilateral blunting of the costophrenic angle
  • Lobulated margins with irregular edges
  • Presence of air-fluid levels

Which of the following statements about pleural effusion is true?

  • It is always associated with large volumes of fluid.
  • It often has irregular density patterns.
  • It can cause unilateral blunting of the costophrenic angle. (correct)
  • It is typically bilateral.

How does large pleural effusion typically present in imaging studies?

<p>With a homogeneous density and meniscus appearance (A)</p> Signup and view all the answers

What specific sign is used to indicate the presence of pleural effusion?

<p>Meniscus sign (B)</p> Signup and view all the answers

What is the primary condition characterized by low levels of albumin in the blood?

<p>Hypoalbuminemia (A)</p> Signup and view all the answers

In which areas of the body can hypoalbuminemia primarily lead to fluid accumulation?

<p>Pleural and abdominal cavities (A)</p> Signup and view all the answers

Which of the following best describes the relationship between hypoalbuminemia and fluid distribution in the body?

<p>It can cause fluid to shift from the abdomen to the thorax. (D)</p> Signup and view all the answers

Hypoalbuminemia is most closely associated with which of the following physiological effects?

<p>Decreased oncotic pressure (C)</p> Signup and view all the answers

What is a possible consequence of hypoalbuminemia affecting the thorax?

<p>Pleural effusion (B)</p> Signup and view all the answers

Study Notes

Pleural Effusion

  • Pleural effusion occurs when over 200 ml of fluid accumulates in the pleural space.
  • Typically, the fluid is seen as a unilateral blunting of the costophrenic angle on a chest X-ray.
  • Pleural effusion may appear with homogeneous density and a meniscus-shaped margin (meniscus sign) on a chest X-ray.
  • Large effusions can displace structures from the abdomen to the thorax.

Causes of Pleural Effusion

  • Transudative effusions result from increased hydrostatic pressure or decreased oncotic pressure.

Hypoalbuminemia

  • Hypoalbuminemia, or low serum albumin, can cause decreased oncotic pressure. Causes include:
    • Nephrotic syndrome
    • Liver disease
    • Malnutrition

Transudative Effusions

  • Common causes include:
    • Congestive heart failure
    • Cirrhosis
    • Nephrotic syndrome
    • Hypothyroidism

Exudative Effusions

  • Common causes include:
    • Pneumonia
    • Lung cancer
    • Pulmonary embolism (PE)

Atelectasis

  • Atelectasis is a collapse or incomplete expansion of a lung.

Empyema

  • Empyema is an accumulation of pus in the pleural cavity.
    • Etiology
      • Most common cause is pneumonia.
      • Less common causes include:
        • Infected hemothorax
        • Ruptured lung abscess
        • Esophageal tear
        • Thoracic trauma
    • Classification
      • Stage I (exudative): Accumulation of fluid and pus.
      • Stage II (fibrinopurulent): Aggregation of fibrin deposits that form septations and pockets within the pleural cavity.
      • Stage III (organizing): Formation of thick fibrous peel on the pleural surface that restricts lung movement.
    • Clinical features:
      • Fever
      • Chills
      • Cough
      • Chest discomfort
    • Diagnosis:
      • Chest X-ray:
        • Opacity with:
          • Meniscus sign
          • Lenticular shape
          • Diffuse consolidation of adjacent lung
      • Ultrasound: Heterogeneous fluid collection
      • Chest CT: Distinctive appearance of empyema fluid
      • Pleural fluid analysis:
        • Exudative effusion:
          • Grossly purulent appearance
          • Positive Gram stain and bacterial culture
          • pH < 7.2
          • Low glucose (< 30-60 mg/dL)
  • Loculated pleural collection: A localized area of fluid accumulation within the pleural space.

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Description

This quiz covers pleural effusion, including its definition, causes, and how it can be identified through chest X-ray findings. It differentiates between transudative and exudative effusions and explores associated conditions like hypoalbuminemia. Test your knowledge on this important thoracic topic!

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