Platelet Inhibitor of Factor IX and Coagulation Process Quiz
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Questions and Answers

What is the role of serotonin in hemostasis?

  • Promotes vasoconstriction (correct)
  • Enhances fibrinolysis
  • Stabilizes fibrin-platelet plug
  • Inhibits platelet activation

    • Which process involves the interaction of coagulation factors on the platelet surface to form a fibrin-platelet plug?

  • Platelet activation
  • Fibrinolysis
  • Fibrin stabilization
  • Fibrin-platelet plug formation (correct)

    • How do intact blood vessels contribute to hemostasis?

  • Increase turbulence in blood flow
  • Maintain blood in a liquid state (correct)
  • Activate platelets
  • Promote coagulation

    • What is the primary role of fibrin stabilization in the hemostatic mechanism?

    <p>Stabilize fibrin-platelet plug</p> Signup and view all the answers

    When does the initiation of fibrinolysis occur in relation to clot formation?

    <p>Simultaneously with clot formation</p> Signup and view all the answers

    What is the primary function of platelet inhibitor of factor IX (PIXI)?

    <p>Inhibits factor XIa &amp; factor IX activation</p> Signup and view all the answers

    In hemostasis, what is the role of the Extrinsic Pathway?

    <p>Initiates contact phase of coagulation</p> Signup and view all the answers

    What is the goal of the Common Pathway in coagulation?

    <p>Formation &amp; stabilization of platelet-fibrin clot</p> Signup and view all the answers

    What is the color change of a hematoma due to?

    <p>Biliverdin</p> Signup and view all the answers

    Which factor is responsible for converting plasminogen into plasmin during fibrinolysis?

    <p>Tissue plasminogen activator</p> Signup and view all the answers

    Which factor is deficient in hemophilia A?

    <p>Factor 8</p> Signup and view all the answers

    How is megakaryopoiesis initiated?

    <p>Totipotent hematopoietic stem cell</p> Signup and view all the answers

    What enzyme converts plasminogen into plasmin?

    <p>Tissue Plasminogen Activator</p> Signup and view all the answers

    What does the Intrinsic Pathway involve in terms of activation?

    <p>Factor XII, XI, HMWK &amp; prekallikrein activation</p> Signup and view all the answers

    Which system is responsible for secondary hemostasis involving fibrin formation?

    <p>Coagulation System</p> Signup and view all the answers

    What clears fibrin split products in the fibrinolytic system?

    <p>Macrophages</p> Signup and view all the answers

    Which factor is consumed during clotting and found in plasma but not in serum?

    <p>Factor 1</p> Signup and view all the answers

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