Platelet Aggregation and Thrombus Formation Quiz
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Questions and Answers

Which substance promotes vasoconstriction at the site of injury, contributing to hemostasis?

  • Serotonin (correct)
  • Beta-thromboglobulin
  • Plasminogen
  • Platelet-derived growth factor

    • What is the primary function of thromboxane A2 released from platelet membrane phospholipids?

  • Promoting clot lysis
  • Inhibiting the complement system
  • Promoting vasoconstriction at the injury site (correct)
  • Assisting in vessel repair

    • Which substance released from alpha granules in platelets promotes smooth muscle growth for vessel repair?

  • Fibrinogen
  • Platelet-derived growth factor (PDGF) (correct)
  • High-molecular-weight kininogen (HMWK)
  • Platelet factor 4

    • Which substance acts as a chemotactic agent, attracting fibroblasts to assist in vessel repair?

    <p>Beta-thromboglobulin</p> Signup and view all the answers

    Which substance released from alpha granules in platelets inhibits plasmin, preventing excessive clot lysis?

    <p>Alpha-2 antiplasmin</p> Signup and view all the answers

    Which substance released from alpha granules in platelets inhibits the complement system, preventing excessive inflammation?

    <p>C1 esterase inhibitor</p> Signup and view all the answers

    What is the term used to describe the contraction of the blood vessel wall to control bleeding?

    <p>Vasoconstriction</p> Signup and view all the answers

    Which of the following is NOT one of the essential factors required for vascular integrity and resistance to vessel disruption?

    <p>Fibrinogen</p> Signup and view all the answers

    What is the role of circulating platelets in blood vessel injuries?

    <p>Forming clots to prevent bleeding</p> Signup and view all the answers

    Which of the following is a property of adrenocorticosteroids in reducing inflammation?

    <p>Possessing anti-inflammatory properties</p> Signup and view all the answers

    Why is ascorbic acid necessary in the context of collagen synthesis?

    <p>To aid in collagen production</p> Signup and view all the answers

    Which factor released by platelets attracts other cells involved in wound healing to the site of injury?

    <p>Thromboxane A2</p> Signup and view all the answers

    Which of the following is a platelet stimulating agent that causes platelet aggregation?

    <p>All of the above</p> Signup and view all the answers

    What is the role of von Willebrand factor (vWf) in platelet adhesion?

    <p>Both a) and b)</p> Signup and view all the answers

    Which of the following statements about aspirin's effect on platelets is correct?

    <p>All of the above</p> Signup and view all the answers

    What is the sequence of events during platelet secretion?

    <p>Platelets undergo shape change from disk to spherical, granules move to center, granule contents extruded</p> Signup and view all the answers

    What is the role of vasoconstrictors like thromboxane A2 in hemostasis?

    <p>Promote blood clotting by reducing blood flow</p> Signup and view all the answers

    What is the initial event that triggers platelet adhesion after vascular injury?

    <p>Exposure of subendothelial collagen fibers</p> Signup and view all the answers

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