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Platelet Aggregation and Thrombus Formation Quiz

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18 Questions

Which substance promotes vasoconstriction at the site of injury, contributing to hemostasis?

Serotonin

What is the primary function of thromboxane A2 released from platelet membrane phospholipids?

Promoting vasoconstriction at the injury site

Which substance released from alpha granules in platelets promotes smooth muscle growth for vessel repair?

Platelet-derived growth factor (PDGF)

Which substance acts as a chemotactic agent, attracting fibroblasts to assist in vessel repair?

Beta-thromboglobulin

Which substance released from alpha granules in platelets inhibits plasmin, preventing excessive clot lysis?

Alpha-2 antiplasmin

Which substance released from alpha granules in platelets inhibits the complement system, preventing excessive inflammation?

C1 esterase inhibitor

What is the term used to describe the contraction of the blood vessel wall to control bleeding?

Vasoconstriction

Which of the following is NOT one of the essential factors required for vascular integrity and resistance to vessel disruption?

Fibrinogen

What is the role of circulating platelets in blood vessel injuries?

Forming clots to prevent bleeding

Which of the following is a property of adrenocorticosteroids in reducing inflammation?

Possessing anti-inflammatory properties

Why is ascorbic acid necessary in the context of collagen synthesis?

To aid in collagen production

Which factor released by platelets attracts other cells involved in wound healing to the site of injury?

Thromboxane A2

Which of the following is a platelet stimulating agent that causes platelet aggregation?

All of the above

What is the role of von Willebrand factor (vWf) in platelet adhesion?

Both a) and b)

Which of the following statements about aspirin's effect on platelets is correct?

All of the above

What is the sequence of events during platelet secretion?

Platelets undergo shape change from disk to spherical, granules move to center, granule contents extruded

What is the role of vasoconstrictors like thromboxane A2 in hemostasis?

Promote blood clotting by reducing blood flow

What is the initial event that triggers platelet adhesion after vascular injury?

Exposure of subendothelial collagen fibers

Test your knowledge on the process of platelet aggregation, fibrinogen's role in binding platelets together, and the formation of thrombus. Learn how fibrinogen and ionized calcium contribute to the consolidation and stabilization of platelet plugs.

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