Platelet Aggregation and Thrombus Formation Quiz

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Questions and Answers

Which substance promotes vasoconstriction at the site of injury, contributing to hemostasis?

  • Serotonin (correct)
  • Beta-thromboglobulin
  • Plasminogen
  • Platelet-derived growth factor

What is the primary function of thromboxane A2 released from platelet membrane phospholipids?

  • Promoting clot lysis
  • Inhibiting the complement system
  • Promoting vasoconstriction at the injury site (correct)
  • Assisting in vessel repair

Which substance released from alpha granules in platelets promotes smooth muscle growth for vessel repair?

  • Fibrinogen
  • Platelet-derived growth factor (PDGF) (correct)
  • High-molecular-weight kininogen (HMWK)
  • Platelet factor 4

Which substance acts as a chemotactic agent, attracting fibroblasts to assist in vessel repair?

<p>Beta-thromboglobulin (B)</p> Signup and view all the answers

Which substance released from alpha granules in platelets inhibits plasmin, preventing excessive clot lysis?

<p>Alpha-2 antiplasmin (A)</p> Signup and view all the answers

Which substance released from alpha granules in platelets inhibits the complement system, preventing excessive inflammation?

<p>C1 esterase inhibitor (B)</p> Signup and view all the answers

What is the term used to describe the contraction of the blood vessel wall to control bleeding?

<p>Vasoconstriction (A)</p> Signup and view all the answers

Which of the following is NOT one of the essential factors required for vascular integrity and resistance to vessel disruption?

<p>Fibrinogen (B)</p> Signup and view all the answers

What is the role of circulating platelets in blood vessel injuries?

<p>Forming clots to prevent bleeding (C)</p> Signup and view all the answers

Which of the following is a property of adrenocorticosteroids in reducing inflammation?

<p>Possessing anti-inflammatory properties (C)</p> Signup and view all the answers

Why is ascorbic acid necessary in the context of collagen synthesis?

<p>To aid in collagen production (D)</p> Signup and view all the answers

Which factor released by platelets attracts other cells involved in wound healing to the site of injury?

<p>Thromboxane A2 (B)</p> Signup and view all the answers

Which of the following is a platelet stimulating agent that causes platelet aggregation?

<p>All of the above (D)</p> Signup and view all the answers

What is the role of von Willebrand factor (vWf) in platelet adhesion?

<p>Both a) and b) (B)</p> Signup and view all the answers

Which of the following statements about aspirin's effect on platelets is correct?

<p>All of the above (D)</p> Signup and view all the answers

What is the sequence of events during platelet secretion?

<p>Platelets undergo shape change from disk to spherical, granules move to center, granule contents extruded (B)</p> Signup and view all the answers

What is the role of vasoconstrictors like thromboxane A2 in hemostasis?

<p>Promote blood clotting by reducing blood flow (A)</p> Signup and view all the answers

What is the initial event that triggers platelet adhesion after vascular injury?

<p>Exposure of subendothelial collagen fibers (D)</p> Signup and view all the answers

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