Platelet Activation and Thrombus Formation
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Questions and Answers

What is believed to be a necessary prerequisite for thrombus formation under high shear stress in arteries?

  • Platelet adherence and activation (correct)
  • Infectious agents
  • Vessel disruption via catheter placement
  • Metabolic abnormalities

    • What can trigger thrombosis by exposing von Willebrand factor and tissue factor?

  • Metabolic abnormalities
  • Severe endothelial injury (correct)
  • Inflammatory mediators
  • Abnormal blood flow

    • What is referred to as endothelial activation or dysfunction?

  • Prothrombotic alterations
  • Metabolic abnormalities
  • Inflammation and other noxious stimuli (correct)
  • Physical injury

    • What are cardiac and arterial clots typically rich in?

    <p>Platelets</p> Signup and view all the answers

    What provides part of the reasoning behind the use of aspirin and other platelet inhibitors in coronary artery disease and acute myocardial infarction?

    <p>Endothelial injury leading to platelet activation</p> Signup and view all the answers

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