Podcast
Questions and Answers
What is the role of endothelial cells in preventing inappropriate thrombi formation?
What is the role of endothelial cells in preventing inappropriate thrombi formation?
- Mediating platelet adhesion to exposed subendothelium
- Containing binding sites for von Willebrand Factor (vWF)
- Expressing collagen and tissue factor
- Releasing tissue plasminogen activator and urokinase (correct)
Which factor is deficient in Hemophilia C?
Which factor is deficient in Hemophilia C?
- Factor II
- Factor IIa
- Factor XIII
- Factor XI (correct)
What is the main function of von Willebrand Factor (vWF) in the formation of the platelet plug?
What is the main function of von Willebrand Factor (vWF) in the formation of the platelet plug?
- Gluing platelets together by fibrinogen
- Exposing thrombin (T) to activate platelets
- Shutting off the coagulation cascade in the presence of Factor IIa (thrombin)
- Mediating platelet adhesion to exposed subendothelium (correct)
What triggers the activation of platelets after binding to the subendothelial tissue?
What triggers the activation of platelets after binding to the subendothelial tissue?
Which component is expressed by subendothelium to kick off the coagulation cascade?
Which component is expressed by subendothelium to kick off the coagulation cascade?
What is the function of activated Protein C?
What is the function of activated Protein C?
What is the physiological inhibitor that activates Protein C?
What is the physiological inhibitor that activates Protein C?
In what form does Protein S exist in the circulation?
In what form does Protein S exist in the circulation?
What is the function of Protein S?
What is the function of Protein S?
Which enzyme activates Protein C?
Which enzyme activates Protein C?
Which factor functions as a cofactor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa?
Which factor functions as a cofactor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa?
What is the main role of Thromboxane A2 (TXA2) in platelet activation?
What is the main role of Thromboxane A2 (TXA2) in platelet activation?
Which molecule is the inactive hydrolysis product of prostacyclin (PGI2)?
Which molecule is the inactive hydrolysis product of prostacyclin (PGI2)?
What is the most potent endogenous inhibitor of platelet aggregation so far discovered?
What is the most potent endogenous inhibitor of platelet aggregation so far discovered?
What does protein C do in the blood coagulation cascade?
What does protein C do in the blood coagulation cascade?
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