15 Questions
What is the role of endothelial cells in preventing inappropriate thrombi formation?
Releasing tissue plasminogen activator and urokinase
Which factor is deficient in Hemophilia C?
Factor XI
What is the main function of von Willebrand Factor (vWF) in the formation of the platelet plug?
Mediating platelet adhesion to exposed subendothelium
What triggers the activation of platelets after binding to the subendothelial tissue?
Exposure of thrombin (T)
Which component is expressed by subendothelium to kick off the coagulation cascade?
Collagen
What is the function of activated Protein C?
Inhibiting Factors V and VIII
What is the physiological inhibitor that activates Protein C?
Activated Thrombomodulin
In what form does Protein S exist in the circulation?
Complex form bound to Protein C
What is the function of Protein S?
Regulating anticoagulation and inflammation
Which enzyme activates Protein C?
Thrombin
Which factor functions as a cofactor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa?
Factor VIII (FVIII)
What is the main role of Thromboxane A2 (TXA2) in platelet activation?
Recruitment of additional platelets to the site of injury
Which molecule is the inactive hydrolysis product of prostacyclin (PGI2)?
6 keto PGF1 alpha
What is the most potent endogenous inhibitor of platelet aggregation so far discovered?
Prostacyclin (PGI2)
What does protein C do in the blood coagulation cascade?
Inhibits thrombin generation
Test your knowledge of plasminogen activation and its conversion to the active form Plasmin by Tissue Plasminogen Activator (t-PA) and Urokinase. Learn about the breakdown of fibrin and the formation of D-dimer.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
