Functional and Non-Functional Plasma Enzymes Quiz and Flashcards

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Questions and Answers

What are functional enzymes in blood plasma?

Functional enzymes in blood plasma are those that are present at all times in the circulation and perform a physiologic function, such as lipoprotein lipase, pseudocholinestrase, and enzymes of blood coagulation.

What are the sources of non-functional plasma enzymes?

Sources of non-functional plasma enzymes include an increase in the rate of enzyme synthesis, increased permeability of cell membrane as in tissue hypoxia, and cell damage with the release of its content of enzymes into the blood.

What causes an increase in the levels of non-functional plasma enzymes?

Tissue damage or necrosis resulting from injury or disease is generally accompanied by an increase in the levels of several non-functional plasma enzymes.

What is the medical importance of non-functional plasma enzymes?

The measurement of non-functional enzymes is important for the diagnosis of diseases, as diseases of different organs cause elevation of different plasma enzymes. Signup and view all the answers

What are the examples of functional enzymes in blood plasma?

Examples of functional enzymes in blood plasma include lipoprotein lipase, pseudocholinestrase, and enzymes of blood coagulation. Signup and view all the answers

Explain the difference between functional and non-functional enzymes in blood plasma.

Functional enzymes perform a physiologic function in the blood at all times, while non-functional enzymes arise from the routine normal destruction of cells and their physiologic function is unknown. Signup and view all the answers

What are the medical implications of an increase in non-functional plasma enzymes?

An increase in non-functional plasma enzymes is indicative of tissue damage or necrosis resulting from injury or disease, and is used in the diagnosis of diseases of different organs. Signup and view all the answers

What are the three sources of non-functional plasma enzymes?

The sources of non-functional plasma enzymes include an increase in the rate of enzyme synthesis, increased permeability of cell membrane as in tissue hypoxia, and cell damage with the release of its content of enzymes into the blood. Signup and view all the answers

What are the examples of functional enzymes in blood plasma?

Examples of functional enzymes in blood plasma include lipoprotein lipase, pseudocholinestrase, and enzymes of blood coagulation. Signup and view all the answers

Why are several enzymes used in the diagnosis of diseases?

Several enzymes are used in the diagnosis of diseases because diseases of different organs cause elevation of different plasma enzymes, making their measurement important for diagnosis. Signup and view all the answers

Study Notes

Functional Enzymes in Blood Plasma

Functional enzymes in blood plasma are proteins that facilitate chemical reactions in the body
They are produced by cells and tissues and released into the bloodstream
Examples of functional enzymes in blood plasma include:
- Aspartate transaminase (AST)
- Alanine transaminase (ALT)
- Lactate dehydrogenase (LDH)
- Creatine kinase (CK)

Non-Functional Enzymes in Blood Plasma

Non-functional enzymes in blood plasma are proteins that are not involved in normal metabolic reactions
They are produced by cells and tissues in response to cellular damage or death
Sources of non-functional plasma enzymes include:
- Cellular injury or death
- Inflammation
- Cancer

Increase in Non-Functional Plasma Enzymes

An increase in non-functional plasma enzymes can be caused by:
- Cellular damage or death
- Inflammation
- Cancer
- Liver or muscle damage
This increase can be used as a diagnostic tool for various diseases

Medical Importance of Non-Functional Plasma Enzymes

Non-functional plasma enzymes are important diagnostic tools for various diseases
They can indicate cellular damage or death, inflammation, or cancer
Elevated levels of non-functional enzymes can be used to monitor disease progression and treatment effectiveness

Difference Between Functional and Non-Functional Enzymes

Functional enzymes are involved in normal metabolic reactions
Non-functional enzymes are produced in response to cellular damage or death
Functional enzymes are produced by healthy cells and tissues, while non-functional enzymes are produced by damaged or dying cells

Medical Implications of Non-Functional Plasma Enzymes

An increase in non-functional plasma enzymes can indicate underlying disease or cellular damage
Elevated levels of non-functional enzymes can be used to diagnose and monitor diseases such as:
- Liver disease
- Muscular dystrophy
- Cancer

Sources of Non-Functional Plasma Enzymes

There are three main sources of non-functional plasma enzymes:
- Cellular injury or death
- Inflammation
- Cancer

Importance of Enzymes in Diagnosis

Enzymes are used in the diagnosis of diseases because they are specific to certain tissues and organs
Elevated levels of specific enzymes can indicate damage or disease in specific tissues or organs
Enzymes are used in conjunction with other diagnostic tools to provide a complete picture of a patient's health

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Description

Test your knowledge of the classification of enzymes in blood plasma, including functional and non-functional enzymes, their physiological functions, and synthesis. Explore the role of enzymes like lipoprotein lipase, pseudocholinesterase, and blood coagulation enzymes.