24 Questions
What is the enzyme that converts PF-KINASE-2 into F-2,6-BISPHOSPHATASE?
Protein kinase A
What happens to glucagon secretion when blood glucose levels drop?
It increases
What happens when glucagon binds receptors on liver cells?
It activates adenylyl cyclase
What is the role of cAMP in the regulation of PKA?
It binds to the regulatory subunits of PKA
What happens to the bifunctional PFK-2/F-2,6-BPase when it is phosphorylated by PKA?
It acts as a phosphatase
What happens to the liver when it stops consuming glucose?
It becomes gluconeogenic
What happens to pancreatic insulin production when blood glucose levels drop?
It falls
What is the effect of glucagon on liver cells?
It activates gluconeogenesis
What is the role of PKA in the interconversion of PF-KINASE-2 and F-2,6-BISPHOSPHATASE?
It phosphorylates PF-KINASE-2
What is the effect of circulating glucagon on blood glucose levels?
It increases blood glucose levels
What is the effect of phosphorylation on the activity of the bifunctional PFK-2/F-2,6-BPase?
It activates its phosphatase activity
What is the effect of falling blood glucose levels on insulin production?
It decreases insulin production
What is the enzyme that converts PF-KINASE-2 into F-2,6-BISPHOSPHATASE?
Protein kinase A
What happens to glucagon secretion when blood glucose levels drop?
It increases
What happens when glucagon binds receptors on liver cells?
It activates adenylyl cyclase
What is the role of cAMP in the regulation of PKA?
It binds to the regulatory subunits of PKA
What happens to the bifunctional PFK-2/F-2,6-BPase when it is phosphorylated by PKA?
It acts as a phosphatase
What happens to the liver when it stops consuming glucose?
It becomes gluconeogenic
What happens to pancreatic insulin production when blood glucose levels drop?
It falls
What is the effect of glucagon on liver cells?
It activates gluconeogenesis
What is the role of PKA in the interconversion of PF-KINASE-2 and F-2,6-BISPHOSPHATASE?
It phosphorylates PF-KINASE-2
What is the effect of circulating glucagon on blood glucose levels?
It increases blood glucose levels
What is the effect of phosphorylation on the activity of the bifunctional PFK-2/F-2,6-BPase?
It activates its phosphatase activity
What is the effect of falling blood glucose levels on insulin production?
It decreases insulin production
Test your knowledge on the regulation of glucose metabolism with our quiz on PKA and F-2,6-BP! Learn about the conversion of bifunctional enzyme PF-KINASE-2, the role of cAMP-dependent protein kinase A (PKA), and how hormones like glucagon impact glucose levels. Put your understanding to the test with our quiz today!
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