Pituitary Gland Disorders: Dwarfism & Gigantism

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Questions and Answers

A deficiency in the secretion of Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) from the anterior pituitary gland would most likely result in which condition?

  • Acromegaly due to excessive bone growth
  • Diabetes insipidus due to decreased water reabsorption
  • Sterility due to impaired gamete production (correct)
  • Cushing's syndrome due to elevated cortisol levels

Fertility drugs that stimulate the release of FSH and LH can increase the chance of multiple births because these hormones directly promote:

  • the maturation and release of multiple eggs during ovulation. (correct)
  • enhanced sperm motility and viability, increasing fertilization rates.
  • increased uterine lining thickness, supporting multiple implantations.
  • reduced levels of progesterone, leading to multiple pregnancies.

Antidiuretic hormone (ADH), also known as vasopressin, primarily targets which organ to regulate water balance in the body?

  • Pancreas
  • Adrenal glands
  • Liver
  • Kidneys (correct)

Diabetes insipidus, resulting from hyposecretion of ADH, is characterized by which of the following sets of symptoms?

<p>Frequent urination and intense thirst (A)</p> Signup and view all the answers

Unlike diabetes mellitus, the urine of a person with untreated diabetes insipidus is described as 'insipid'. This term refers to the urine being:

<p>dilute and lacking in distinct characteristics. (D)</p> Signup and view all the answers

If a patient is diagnosed with diabetes insipidus due to insufficient ADH secretion, which part of the pituitary gland is most likely malfunctioning?

<p>Posterior pituitary (C)</p> Signup and view all the answers

A patient presents with symptoms of excessive thirst and frequent urination. Blood tests reveal normal glucose levels. Which hormonal deficiency is the most likely cause of these symptoms?

<p>Antidiuretic Hormone (ADH) (D)</p> Signup and view all the answers

What is the primary role of the pituitary gland in the human body?

<p>Secreting hormones that influence various functions such as metabolism, growth, and reproduction. (B)</p> Signup and view all the answers

A child is diagnosed with pituitary dwarfism. Which of the following hormonal imbalances is the most likely cause?

<p>Hypo-secretion of growth hormone (GH). (D)</p> Signup and view all the answers

Excessive secretion of growth hormone during childhood leads to what condition?

<p>Gigantism (A)</p> Signup and view all the answers

Acromegaly is typically caused by hyper-secretion of growth hormone in adulthood. Why does this condition primarily affect the bones of the face, hands, and feet rather than overall height?

<p>The epiphyseal plates in long bones have already fused, preventing further lengthening of these bones. (D)</p> Signup and view all the answers

Which condition is a direct result of low secretion of both follicle-stimulating hormone (FSH) and luteinizing hormone (LH)?

<p>Sterility (B)</p> Signup and view all the answers

How does gigantism differ from acromegaly in terms of the patient's stage of development?

<p>Gigantism occurs in childhood before the epiphyseal plates fuse, whereas acromegaly occurs in adulthood after the epiphyseal plates have fused. (D)</p> Signup and view all the answers

A patient exhibits increased bone size in their hands and feet along with a thickening of the facial features. Height is normal. What is this condition and its cause?

<p>Acromegaly due to GH hyper-secretion after puberty (A)</p> Signup and view all the answers

If a tumor in the anterior pituitary caused a decrease in GH what would likely be the result?

<p>A child patient might be diagnosed with pituitary dwarfism. (C)</p> Signup and view all the answers

Flashcards

Pituitary Gland

A small gland secreting hormones affecting metabolism, growth, and reproduction.

Growth Hormone (GH)

Promotes bone and muscle growth, produced in the anterior pituitary gland.

Pituitary Dwarfism

Too little growth hormone secreted during childhood, resulting in slow growth and short stature (under four feet).

Gigantism

Excessive growth hormone secretion during childhood, leading to rapid growth and extreme height (8-9 feet).

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Acromegaly

Hyper-secretion of growth hormone in adulthood. Bones of the face, hands, and feet continue to grow.

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Cause of Acromegaly

Condition mainly caused by a tumor of the pituitary gland.

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Sterility

Failure to produce children (sterile).

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Hormonal cause of Sterility

Low secretion of Follicle stimulating hormone (FSH) and Luteinizing hormone (LH).

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FSH (Follicle-Stimulating Hormone)

Stimulates egg and sperm production.

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LH (Luteinizing Hormone)

Triggers ovulation in females and stimulates testosterone production in males.

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ADH (Antidiuretic Hormone)

A hormone that increases water absorption by the kidneys (decreases urination).

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Diabetes Insipidus

Rare diabetes caused by ADH deficiency, leading to frequent urination and thirst.

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ADH Location

Located in the posterior pituitary gland; releases ADH.

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Insipid Urine

Watery urine, lacking usual solutes, due to ADH deficiency.

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Study Notes

  • The pituitary gland secretes hormones affecting metabolism, water retention, growth, development, and reproduction.
  • These hormones are crucial for maintaining homeostasis.
  • Imbalances in hormone secretion can lead to disorders like dwarfism, gigantism, sterility, and diabetes insipidus.

Pituitary Dwarfism

  • Growth hormone (GH), produced in the anterior pituitary gland, promotes growth.
  • In children, GH stimulates bone and muscle growth for normal physical development.
  • Hypo-secretion of GH during childhood leads to pituitary dwarfism.
  • This causes slow growth of all body structures, resulting in a proportionately small body, typically not exceeding four feet in height.

Gigantism and Acromegaly

  • Hyper-secretion of GH during childhood causes gigantism.
  • Gigantism results in rapid bone and muscle growth, leading to excessive height, potentially reaching 8 or 9 feet.
  • Individuals with gigantism maintain proportionate body structures.
  • Acromegaly occurs when there is a hyper-secretion of growth hormone during adulthood.
  • After the epiphyseal plates fuse, the long bones stop growing so height is unaffected.
  • Only bones in the jaw, face, feet, and hands continue to grow.
  • Acromegaly is often caused by a pituitary gland tumor.

Sterility

  • The anterior pituitary gland secretes follicle-stimulating hormone (FSH) and luteinizing hormone (LH), essential for reproduction.
  • FSH stimulates the production of egg and sperm.
  • LH triggers ovulation in females and stimulates testosterone production in males.
  • Hypo-secretion of FSH and LH can result in sterility, or the inability to have children.
  • Fertility drugs can stimulate the release of FSH and LH, leading to multiple ovulations and potentially multiple births.

Diabetes Insipidus

  • Antidiuretic hormone (ADH), also known as vasopressin, is secreted by the posterior pituitary gland.
  • ADH increases water absorption by the kidneys, reducing urination.
  • Hypo-secretion of ADH leads to diabetes insipidus, a rare form of diabetes.
  • Diabetes insipidus causes the body to lose excessive water through urination, leading to constant thirst and frequent urination.
  • The term 'insipid' refers to the tasteless, dilute urine characteristic of this condition.

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