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Questions and Answers
What is the primary arterial supply to the pancreas?
What is the primary arterial supply to the pancreas?
Which cells in the Islets of Langerhans are responsible for producing insulin?
Which cells in the Islets of Langerhans are responsible for producing insulin?
What happens to the thymus after puberty?
What happens to the thymus after puberty?
Which of the following correctly describes the morphology of the pancreas?
Which of the following correctly describes the morphology of the pancreas?
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What is the function of the thymus gland?
What is the function of the thymus gland?
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What type of cells primarily populate the cortex of the thymus?
What type of cells primarily populate the cortex of the thymus?
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What is the primary function of Leydig cells in the testes?
What is the primary function of Leydig cells in the testes?
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Which component is NOT found in the medulla of the thymus?
Which component is NOT found in the medulla of the thymus?
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What does the tunica albuginea refer to in both the testes and the ovaries?
What does the tunica albuginea refer to in both the testes and the ovaries?
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What is a primary characteristic of Hassall's corpuscles?
What is a primary characteristic of Hassall's corpuscles?
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What condition is associated with the accumulation of fluid in the tunica vaginalis?
What condition is associated with the accumulation of fluid in the tunica vaginalis?
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Which structure in the ovaries is responsible for hormone production?
Which structure in the ovaries is responsible for hormone production?
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What changes in the thymus after puberty?
What changes in the thymus after puberty?
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What is the shape of the right adrenal gland?
What is the shape of the right adrenal gland?
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Where does the left suprarenal vein drain?
Where does the left suprarenal vein drain?
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Which zone of the adrenal cortex is responsible for producing mineralocorticoids such as aldosterone?
Which zone of the adrenal cortex is responsible for producing mineralocorticoids such as aldosterone?
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What is the histological characteristic of the zona fasciculata in the adrenal cortex?
What is the histological characteristic of the zona fasciculata in the adrenal cortex?
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What supplies blood to the adrenal glands?
What supplies blood to the adrenal glands?
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Which adrenal cortex layer is known for secreting small amounts of sex hormones?
Which adrenal cortex layer is known for secreting small amounts of sex hormones?
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What type of fat surrounds the renal fascia?
What type of fat surrounds the renal fascia?
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What is the venous drainage of the right suprarenal vein?
What is the venous drainage of the right suprarenal vein?
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What hormones are secreted by the adrenal medulla?
What hormones are secreted by the adrenal medulla?
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What condition is characterized by hypoadrenalism due to autoimmune adrenalitis?
What condition is characterized by hypoadrenalism due to autoimmune adrenalitis?
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Which hormones are produced by the pineal gland?
Which hormones are produced by the pineal gland?
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What is a characteristic feature of chromaffin cells in the adrenal medulla?
What is a characteristic feature of chromaffin cells in the adrenal medulla?
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What is the function of the pineal gland in relation to light?
What is the function of the pineal gland in relation to light?
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Which of the following describes Conn's syndrome?
Which of the following describes Conn's syndrome?
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Which anatomical feature connects the pineal gland to the brain?
Which anatomical feature connects the pineal gland to the brain?
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What is the primary function of the growth hormone produced by the anterior pituitary?
What is the primary function of the growth hormone produced by the anterior pituitary?
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What is the role of adrenal medullary hormones during stress?
What is the role of adrenal medullary hormones during stress?
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Which structure connects the pituitary gland to the hypothalamus?
Which structure connects the pituitary gland to the hypothalamus?
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What is the histological feature of chromophobes found in the pars distalis of the anterior pituitary?
What is the histological feature of chromophobes found in the pars distalis of the anterior pituitary?
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Which hormone is primarily responsible for stimulating the interstitial cells of the testes?
Which hormone is primarily responsible for stimulating the interstitial cells of the testes?
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What is a common consequence of a pituitary adenoma producing excessive growth hormone?
What is a common consequence of a pituitary adenoma producing excessive growth hormone?
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Which region of the pituitary gland secretes melanocyte stimulating hormone (MSH)?
Which region of the pituitary gland secretes melanocyte stimulating hormone (MSH)?
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What role do pituicytes serve in the posterior pituitary?
What role do pituicytes serve in the posterior pituitary?
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The failure of hormone production due to blockage of arterial supply in the pituitary gland is known as:
The failure of hormone production due to blockage of arterial supply in the pituitary gland is known as:
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Which of the following hormones released from the posterior pituitary constricts arterioles and raises blood pressure?
Which of the following hormones released from the posterior pituitary constricts arterioles and raises blood pressure?
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What is the anatomical location of the pituitary gland?
What is the anatomical location of the pituitary gland?
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Study Notes
Pituitary Gland
- Located in the hypophyseal fossa (sella turcica) beneath the hypothalamus, connected by the infundibulum.
- Covered by the diaphragma sella, a fold of dura mater.
- Related anatomically to the cavernous sinus and optic chiasma.
Pituitary Gland Lobes
- Anterior Lobe: Comprises pars distalis, pars tuberalis, and pars intermedia.
- Posterior Lobe: Includes pars nervosa, infundibular stalk, and median eminence.
Blood Supply and Connections
- Supplied by superior and inferior hypophyseal arteries, branches of the internal carotid artery.
- Posterior lobe receives nerve fibers from the supraoptic and paraventricular nuclei (hypothalamo-hypophyseal tract).
- Anterior lobe links to the hypothalamus via the hypothalamo-hypophyseal portal system.
Histology of the Pituitary Gland
- Fibro-elastic capsule covers the gland; trabeculae carry blood vessels into pars distalis.
- Pars Distalis: Contains chromophobes and chromophil cells; acidophils and basophils are present.
- Pars Tuberalis: Features cuboidal cells with central nuclei.
- Pars Intermedia: Secretes melanocyte-stimulating hormone (MSH).
Posterior Pituitary
- Characterized by non-myelinated axons and Herring bodies (expanded terminal ends).
- Contains pituicytes, neuroglial cells with branching processes and granules.
Hormones and Their Effects
-
Anterior Pituitary:
- Growth hormone: Overall growth promotion.
- Follicle Stimulating Hormone (FSH): Promotes ovarian follicles and sperm production.
- Luteinizing Hormone (LH): Stimulates ovulation and testicular interstitial cells.
- Thyroid Stimulating Hormone (TSH): Acts on the thyroid gland.
- Adrenocorticotropic Hormone (ACTH): Targets the adrenal cortex.
-
Posterior Pituitary:
- Antidiuretic hormone (vasopressin): Constricts arterioles and raises blood pressure.
- Oxytocin: Acts on uterine muscle and mammary gland ducts.
Disorders of the Pituitary Gland
- Adenoma: Excessive hormone production leading to conditions like Cushing's disease and gigantism.
- Panhypopituitarism: Rare failure of hormone production due to blockage of arterial supply.
Adrenal Glands
- Paired, yellowish glands located retroperitoneally on the kidneys' upper poles.
- Right adrenal gland: Pyramidal shape; related to the liver and inferior vena cava.
- Left adrenal gland: Crescentic shape; associated with the pancreas and stomach.
Adrenal Gland Blood Supply
- Supplied by superior suprarenal (from inferior phrenic artery), middle suprarenal (from aorta), and inferior suprarenal arteries (from renal artery).
- Venous drainage via suprarenal veins: right vein drains into the inferior vena cava, left vein drains into the renal vein.
Histology of Adrenal Gland
- Adrenal cortex: Has three zones (glomerulosa, fasciculata, reticularis) producing various hormones.
- Adrenal medulla: Contains chromaffin cells that secrete adrenaline and noradrenaline.
Adrenal Gland Disorders
- Hypoadrenalism: Results in Addison's disease, marked by weakness and low sodium.
- Hyperadrenalism: Can lead to Cushing's syndrome and Conn's syndrome, often due to tumors.
Pineal Gland
- Small, spherical gland located inferior to the posterior corpus callosum.
- Synthesizes melatonin in response to darkness.
Histology of the Pineal Gland
- Composed of pinealocytes (modified neurons) and neuroglial cells.
- Contains calcium and magnesium phosphate, with age-related basophilic bodies (pineal sand).
Pancreas
- Functions as both exocrine and endocrine gland; lies posterior to the peritoneum.
- Supplied by splenic artery and superior/inferior pancreaticoduodenal arteries.
Histology of the Pancreas
- Exocrine secretory acini and Islets of Langerhans scattered throughout the exocrine tissue.
- Alpha cells produce glucagon, beta cells produce insulin, and delta cells produce gastrin.
Thymus
- Largest during puberty, gradually replaced by fatty tissue afterward.
- Produces hormones regulating immune cell production, crucial for T cell maturation.
Histology of the Thymus
- Composed of a cortex (basophilic) containing T lymphocytes and a medulla with Hassall's corpuscles.
- Supports framework provided by epithelial cells, with a loose collagenous capsule.
Testes
- Encapsulated in dense fibrous tissue (tunica albuginea), divided into lobules containing seminiferous tubules.
- Leydig cells produce testosterone.
Disorders of the Testes
- Testicular cancer, varicocele, and hydrocele testis are common disorders.
Ovaries
- Located in the pelvic region, encapsulated by tunica albuginea.
- Comprises germinal epithelium, cortex, and medulla with various hormone-producing structures.
Ovarian Disorders
- Includes ovarian cysts, polycystic ovary syndrome, ovarian cancer, and changes seen in menopause.
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Description
Explore the intricate details of the pituitary gland, its location, and its relations to surrounding structures. This quiz covers the anatomy, lobes, and important connections of the pituitary gland, including its role in hormonal regulation.