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Phytotherapy of GIT Disorders

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Questions and Answers

What is the main active constituent responsible for the laxative effect of senna leaves extract?

Sennoside A (correct)
Sennoside C
Rhein-anthrone
Peppermint oil

What is the primary mechanism of action of senna leaves extract in treating constipation?

Inhibiting fluid re-absorption (correct)
Reducing gut motility
Increasing colon transit time
Stimulating the digestive enzymes

What is the possible side effect of high doses of senna leaves extract?

Frequent bowel movements
Abdominal pain and flatulence
Increased gut motility
Dehydration and loss of electrolytes (correct)

What is the role of bacteria in the large intestine in the mechanism of laxative action of senna leaves extract?

Converting the sennosides into rhein-anthrone (B) Signup and view all the answers

What is the composition of each soft gelatin capsule of Mentholax?

Purified senna extract 20mg, peppermint oil 100mg (B) Signup and view all the answers

What is the indication of Mentholax in treating gastrointestinal disorders?

Habitual constipation accompanied with flatulence (B) Signup and view all the answers

What precaution should be taken with patients taking certain medications when using senna?

Take with caution, especially with cardiac glycosides, antiarrhythmics, diuretics, adrenocorticosteroids, or liquorice (A) Signup and view all the answers

What is a contraindication for using senna?

Intestinal obstruction, appendicitis, inflammatory colon diseases, abdominal pain of unknown origin, severe dehydration, or electrolyte depletion (C) Signup and view all the answers

What is a possible side effect of long-term use of senna?

Dependence, disturbance of water and electrolyte balance, and atonic colon with impaired function (B) Signup and view all the answers

What is peppermint oil used for?

Symptomatic relief of digestive disorders, coughs, and colds, and bronchitis (D) Signup and view all the answers

What is a constituent of peppermint essential oil?

Menthol (B) Signup and view all the answers

What is a licensed use of peppermint oil enteric-coated capsules in the United Kingdom?

Treatment of irritable bowel syndrome (B) Signup and view all the answers

What is the effect of peppermint oil on cytochrome enzymes?

It inhibits cytochrome enzymes (D) Signup and view all the answers

What is the precaution that should be taken when using menthol?

It should not be used by children (A) Signup and view all the answers

What is the role of Senna extract in the formula?

It increases the peristaltic movements of the colon (A) Signup and view all the answers

What is the function of peppermint oil in the formula?

It is a carminative and mild antispasmodic (A) Signup and view all the answers

What is the recommended dose of the medication for adults with habitual constipation?

One capsule 3 times daily (A) Signup and view all the answers

What is the composition of each 5g of the granules?

Seeds of Plantago ovata 2.6g, Ispaghula husk 0.11g (A) Signup and view all the answers

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