Phytotherapy of GIT Disorders
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Questions and Answers

What is the main active constituent responsible for the laxative effect of senna leaves extract?

  • Sennoside A (correct)
  • Sennoside C
  • Rhein-anthrone
  • Peppermint oil
  • What is the primary mechanism of action of senna leaves extract in treating constipation?

  • Inhibiting fluid re-absorption (correct)
  • Reducing gut motility
  • Increasing colon transit time
  • Stimulating the digestive enzymes
  • What is the possible side effect of high doses of senna leaves extract?

  • Frequent bowel movements
  • Abdominal pain and flatulence
  • Increased gut motility
  • Dehydration and loss of electrolytes (correct)
  • What is the role of bacteria in the large intestine in the mechanism of laxative action of senna leaves extract?

    <p>Converting the sennosides into rhein-anthrone</p> Signup and view all the answers

    What is the composition of each soft gelatin capsule of Mentholax?

    <p>Purified senna extract 20mg, peppermint oil 100mg</p> Signup and view all the answers

    What is the indication of Mentholax in treating gastrointestinal disorders?

    <p>Habitual constipation accompanied with flatulence</p> Signup and view all the answers

    What precaution should be taken with patients taking certain medications when using senna?

    <p>Take with caution, especially with cardiac glycosides, antiarrhythmics, diuretics, adrenocorticosteroids, or liquorice</p> Signup and view all the answers

    What is a contraindication for using senna?

    <p>Intestinal obstruction, appendicitis, inflammatory colon diseases, abdominal pain of unknown origin, severe dehydration, or electrolyte depletion</p> Signup and view all the answers

    What is a possible side effect of long-term use of senna?

    <p>Dependence, disturbance of water and electrolyte balance, and atonic colon with impaired function</p> Signup and view all the answers

    What is peppermint oil used for?

    <p>Symptomatic relief of digestive disorders, coughs, and colds, and bronchitis</p> Signup and view all the answers

    What is a constituent of peppermint essential oil?

    <p>Menthol</p> Signup and view all the answers

    What is a licensed use of peppermint oil enteric-coated capsules in the United Kingdom?

    <p>Treatment of irritable bowel syndrome</p> Signup and view all the answers

    What is the effect of peppermint oil on cytochrome enzymes?

    <p>It inhibits cytochrome enzymes</p> Signup and view all the answers

    What is the precaution that should be taken when using menthol?

    <p>It should not be used by children</p> Signup and view all the answers

    What is the role of Senna extract in the formula?

    <p>It increases the peristaltic movements of the colon</p> Signup and view all the answers

    What is the function of peppermint oil in the formula?

    <p>It is a carminative and mild antispasmodic</p> Signup and view all the answers

    What is the recommended dose of the medication for adults with habitual constipation?

    <p>One capsule 3 times daily</p> Signup and view all the answers

    What is the composition of each 5g of the granules?

    <p>Seeds of Plantago ovata 2.6g, Ispaghula husk 0.11g</p> Signup and view all the answers

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