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Questions and Answers
What triggers the opening of voltage-gated Na+ channels in sensory receptor neurons?
What triggers the opening of voltage-gated Na+ channels in sensory receptor neurons?
In epithelial sensory receptor cells, what causes the neurotransmitter release?
In epithelial sensory receptor cells, what causes the neurotransmitter release?
Where is the trigger zone of the afferent neuron located in relation to the receptor region?
Where is the trigger zone of the afferent neuron located in relation to the receptor region?
What defines the receptor potential in sensory receptor cells?
What defines the receptor potential in sensory receptor cells?
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How do neuronal sensory receptor cells primarily transmit their signals?
How do neuronal sensory receptor cells primarily transmit their signals?
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What type of channels are involved in propagating an action potential?
What type of channels are involved in propagating an action potential?
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Which structure is NOT considered a part of the visual system?
Which structure is NOT considered a part of the visual system?
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What is the primary role of photoreceptors?
What is the primary role of photoreceptors?
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Which statement best describes action potentials?
Which statement best describes action potentials?
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Where are sensory receptor cells primarily localized in the body?
Where are sensory receptor cells primarily localized in the body?
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Which of the following senses is NOT classified as a special sense?
Which of the following senses is NOT classified as a special sense?
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What type of cells are involved in the process of gustation?
What type of cells are involved in the process of gustation?
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What is the role of accessory tissues in sensory systems?
What is the role of accessory tissues in sensory systems?
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Which type of transport requires energy to move substances across the membrane?
Which type of transport requires energy to move substances across the membrane?
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What occurs during depolarization in excitable cells?
What occurs during depolarization in excitable cells?
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Which of the following correctly describes G protein-coupled receptors?
Which of the following correctly describes G protein-coupled receptors?
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What is the role of the amplifier enzyme in G protein-coupled receptor signal transduction?
What is the role of the amplifier enzyme in G protein-coupled receptor signal transduction?
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Which type of channel opens in response to a mechanical stimulus?
Which type of channel opens in response to a mechanical stimulus?
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How do graded potentials differ from action potentials?
How do graded potentials differ from action potentials?
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What defines the characteristic of a voltage-gated channel?
What defines the characteristic of a voltage-gated channel?
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What is hyperpolarization in excitable cells?
What is hyperpolarization in excitable cells?
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What is the first step in the sensory reception process?
What is the first step in the sensory reception process?
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Which type of sensory receptor is specialized to detect mechanical stimuli?
Which type of sensory receptor is specialized to detect mechanical stimuli?
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What is the role of sensory receptor proteins in the transduction process?
What is the role of sensory receptor proteins in the transduction process?
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How are sensory receptor cells classified?
How are sensory receptor cells classified?
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Which receptor type is involved in the sensation of taste for salty and sour?
Which receptor type is involved in the sensation of taste for salty and sour?
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What does the term 'graded potential' refer to in the context of sensory reception?
What does the term 'graded potential' refer to in the context of sensory reception?
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Which type of sensory receptor is responsible for detecting light?
Which type of sensory receptor is responsible for detecting light?
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What is required for a sufficient stimulus to overcome the specialization of a sensory receptor?
What is required for a sufficient stimulus to overcome the specialization of a sensory receptor?
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Flashcards
Passive Diffusion
Passive Diffusion
Movement of substances across a membrane that doesn't require energy, like following the concentration gradient. Think of a ball rolling downhill.
Transport Proteins
Transport Proteins
Specialized proteins embedded in the cell membrane that help facilitate the movement of molecules across the membrane. Think of a gatekeeper letting specific guests through.
Channels
Channels
A type of transport protein that forms a channel through the membrane, allowing specific molecules to pass through. Think of a tunnel for specific vehicles.
Gated Channels
Gated Channels
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Active Transport
Active Transport
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Primary Active Transport
Primary Active Transport
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Graded Potential
Graded Potential
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Action Potential
Action Potential
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Transduction
Transduction
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Sensory Receptor Proteins
Sensory Receptor Proteins
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Sensory Receptor Cells
Sensory Receptor Cells
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Reception
Reception
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Transmission
Transmission
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Perception
Perception
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Photoreceptor
Photoreceptor
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Chemoreceptor
Chemoreceptor
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Receptor Potential
Receptor Potential
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Sensory Transduction
Sensory Transduction
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Neuronal Sensory Receptor Cell
Neuronal Sensory Receptor Cell
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Epithelial Sensory Receptor Cell
Epithelial Sensory Receptor Cell
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All-or-None Phenomenon
All-or-None Phenomenon
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Voltage-gated channels
Voltage-gated channels
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Special Senses
Special Senses
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Sense of Touch
Sense of Touch
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Sense Organ
Sense Organ
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Sensory System
Sensory System
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Study Notes
Special Senses Sensory Physiology
- Sensory physiology describes how special senses like taste, smell, hearing, balance, and vision function.
- Specialized receptor proteins detect stimuli (e.g., chemicals, pressure, light).
- Receptor cells convert stimuli into changes in membrane potential (graded potentials).
- Signals travel to integrating centers (e.g., brain).
- Perception occurs at these centers, leading to sensory experience.
Membrane Physiology Recap
- Plasma membrane separates the body's fluid compartments.
- It exhibits selective permeability, controlling substance entry/exit.
- Structural components include glycocalyx (carbohydrates), lipid bilayer, proteins (integral & peripheral), cholesterol, glycolipids, and glycoproteins.
- Electrochemical gradients influence substance movement.
Membrane Transport
- Passive diffusion: Lipid-soluble molecules cross the membrane directly.
- Facilitated diffusion: Carrier proteins or channels aid transport.
- Active transport: Energy required to move substances against their concentration gradient.
Transport Proteins – Channels
- Channels are transmembrane proteins.
- Ligand-gated channels open in response to specific molecules.
- Voltage-gated channels open in response to changes in membrane potential.
- Mechanically-gated channels open in response to physical forces.
G Protein-Coupled Receptor Signal Transduction
- G protein-coupled receptors are linked to intracellular signaling pathways.
- A stimulus triggers a conformational change in the receptor, activating a G protein.
- The activated G protein activates an amplifier enzyme, modifying second messengers.
- Second messengers initiate downstream intracellular reactions.
Graded Potentials
- Occur in excitable and non-excitable cells.
- Brief, localized changes in membrane potential.
- Vary in magnitude and duration.
- Decays over distance.
- Can be depolarizing or hyperpolarizing.
Action Potentials
- Occur in specialized cells (neurons & some muscle cells).
- All-or-none response: Threshold must be reached for generation.
- Propagates rapidly along the membrane without decreasing strength.
- Involves voltage-gated ion channels (e.g., Na+ channels).
Reminder: Nervous System
- Afferent neurons transmit signals to the CNS.
- Sensory receptors at the peripheral end of afferent neurons.
- Efferent neurons carry signals from the CNS to effectors (muscles/glands).
- Interneurons connect neurons within the CNS.
The Special Senses
- Special senses are localized in the head region.
- Sensory receptors include distinct cells like photoreceptors (vision), hair cells (hearing/balance), olfactory cells (smell), and taste cells (taste).
- Touch is mediated by general receptors (modified nerves).
Sensory System Example (Visual System)
- Visual system components: Photoreceptors (rods & cones), accessory tissue (iris, cornea), optic nerve, and primary visual cortex.
- Sensory receptor cells are specialized to detect incoming stimuli.
- Sense organs comprise receptor cells and accessory tissues.
- Sensory systems include sense organs, afferent neurons, and CNS processing areas.
Overview of Sensory Reception
- Sensory reception involves stimulus reception, transduction (conversion to electrical signal), transmission to integrating centers, and perception.
Sensory Receptor Cells
- Specialized cells to detect specific stimuli (e.g., chemicals, light, pressure).
- Exhibit receptor proteins for stimulus transduction.
- Respond to specific stimuli and transmit signals to integrating centers.
- Classified by modality (e.g., photoreceptors, chemoreceptors, mechanoreceptors).
Sensory Receptor Proteins
- Ion channels, mechanically- or voltage-gated.
- G protein-coupled receptors.
- Receptor protein conformation changes initiate signals.
Sensory Receptor Cells (Continued)
- Stimulus triggers a receptor potential (graded potential).
- Receptor potentials can lead to action potentials in neurons.
- In non-neuronal cells, receptor potentials trigger neurotransmitter release.
Check Your Knowledge
- Neuronal and epithelial sensory receptors differ in signal transduction mechanisms.
- Sensory receptor cells are both neuronal and non-neuronal.
- Receptor potentials are graded potentials, not action potentials.
- Stimulation of epithelial receptors triggers an action potential at the trigger zone of an afferent neuron.
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Description
Explore the fascinating world of sensory physiology, focusing on how special senses such as taste and vision function. The quiz also covers essential aspects of membrane physiology, including structure and transport mechanisms. Test your understanding of these critical biological concepts.