Podcast
Questions and Answers
What is the result of parabiosis between db/db and Wildtype mice?
What is the result of parabiosis between db/db and Wildtype mice?
Starvation in Wildtype, normal feeding in db/db
What is the effect of leptin mutations on the body?
What is the effect of leptin mutations on the body?
Hyperphagia and obesity as the body does not know about its energy status
Where does leptin mediate its satiating effects?
Where does leptin mediate its satiating effects?
Hypothalamus, specifically in the arcuate nucleus (ARC), ventromedial nucleus (VMN), and lateral hypothalamic area (LHA)
What is the function of NPY/agRP neurons in the arcuate nucleus?
What is the function of NPY/agRP neurons in the arcuate nucleus?
How do orexins trigger appetite responses?
How do orexins trigger appetite responses?
What is the role of leptin in hunger regulation?
What is the role of leptin in hunger regulation?
What is produced by adipocytes in proportion to triglyceride content?
What is produced by adipocytes in proportion to triglyceride content?
What is the result of parabiosis between ob/ob and db/db mice?
What is the result of parabiosis between ob/ob and db/db mice?
What is the effect of leptin on POMC neurons?
What is the effect of leptin on POMC neurons?
How does leptin interact with ghrelin?
How does leptin interact with ghrelin?
