Regulation of BP

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Questions and Answers

What is the primary effect of antidiuretic hormone (ADH) on blood volume?

  • Decreases blood volume by causing vasoconstriction.
  • Has no effect on blood volume.
  • Increases blood volume by promoting water reabsorption. (correct)
  • Decreases blood volume by promoting water loss.

Under what condition is erythropoietin primarily released?

  • High blood volume and high oxygen content.
  • High blood sugar content.
  • Low blood pressure and low oxygen content. (correct)
  • High blood pressure and high oxygen content.

What is the primary mechanism by which atrial natriuretic factor (ANF) reduces blood pressure?

  • Promoting vasoconstriction.
  • Increasing the release of renin.
  • Increasing sodium excretion at the kidneys. (correct)
  • Decreasing water excretion by increasing ADH release.

Which of the following is NOT a function of natriuretic peptides like ANF and BNP?

<p>Reducing sodium excretion at the kidneys. (C)</p> Signup and view all the answers

What triggers the release of atrial natriuretic factor (ANF)?

<p>Excessive stretching of the right atrium during diastole. (B)</p> Signup and view all the answers

What is the primary cause of the pressure exerted by blood on the walls of a vessel?

<p>The contraction of the ventricles (B)</p> Signup and view all the answers

Which of the following best describes diastolic blood pressure?

<p>The minimum pressure during ventricular relaxation (C)</p> Signup and view all the answers

If a patient has a blood pressure reading of 140/90 mm Hg, what condition would they likely be diagnosed with?

<p>Hypertension (A)</p> Signup and view all the answers

What is the effect on blood pressure if cardiac output increases due to an elevated heart rate?

<p>Blood pressure rises (D)</p> Signup and view all the answers

How is mean arterial pressure (MAP) calculated?

<p>Diastolic pressure + 1/3 pulse pressure (A)</p> Signup and view all the answers

What is a typical range for normal mean arterial pressure (MAP)?

<p>70-110 mm Hg (A)</p> Signup and view all the answers

What does an increase in total peripheral resistance (TPR) typically cause?

<p>Increase in blood pressure (A)</p> Signup and view all the answers

What is the effect of a significant decrease (over 10%) in blood volume on blood pressure?

<p>Blood pressure drops (C)</p> Signup and view all the answers

What is the primary definition of blood flow?

<p>The quantity of blood passing through circulation per unit of time (D)</p> Signup and view all the answers

Which of the following best describes how cardiac output affects blood pressure?

<p>Increased cardiac output leads to an increase in blood pressure (A)</p> Signup and view all the answers

In clinical practice, when the term 'blood pressure' is used, it typically refers to the pressure in which part of the circulatory system?

<p>Arteries (B)</p> Signup and view all the answers

Besides heart rate, what other factor significantly affects cardiac output?

<p>Stroke volume (B)</p> Signup and view all the answers

According to Poiseuille's law, how does the radius of a blood vessel affect resistance?

<p>Resistance is inversely proportional to the radius to the fourth power. (A)</p> Signup and view all the answers

How does dehydration affect blood pressure?

<p>It decreases blood pressure because of reduced blood volume (A)</p> Signup and view all the answers

What is the approximate total blood flow in an adult's circulation per minute?

<p>5000 ml/min (D)</p> Signup and view all the answers

Which of the following conditions would lead to an increase in systemic vascular resistance (SVR)?

<p>Dehydration (A)</p> Signup and view all the answers

Which of these options is best described as the force that drives blood flow through the circulatory system?

<p>Pressure differences (B)</p> Signup and view all the answers

Why does pulse pressure decrease as blood flows further from the heart?

<p>Due to elastic rebound in the arteries. (B)</p> Signup and view all the answers

According to Darcy's law, if total peripheral resistance (TPR) increases while mean arterial pressure (MAP) remains constant, what would happen to cardiac output?

<p>Cardiac output would decrease. (B)</p> Signup and view all the answers

During which phase of the cardiac cycle does the pressure in the aorta typically vary?

<p>Both ventricular systole and diastole (B)</p> Signup and view all the answers

What is the primary cause of Korotkoff sounds when measuring blood pressure?

<p>Turbulent blood flow. (C)</p> Signup and view all the answers

Which of the following best describes laminar blood flow?

<p>Smooth flow with the fastest movement at the vessel's center. (C)</p> Signup and view all the answers

How does an increase in blood vessel length affect systemic vascular resistance (SVR)?

<p>SVR increases due to increased surface area and friction. (B)</p> Signup and view all the answers

Which of the following statements is correct regarding blood viscosity and its effect on blood pressure?

<p>Increased blood viscosity requires higher pressure to maintain blood Flow (C)</p> Signup and view all the answers

What is the primary goal of cardiovascular regulation?

<p>To ensure blood flow changes occur appropriately in time and location, without drastically altering blood flow to vital organs. (A)</p> Signup and view all the answers

Which of the following factors is NOT directly involved in the regulation of cardiovascular function?

<p>Dietary intake of sodium. (C)</p> Signup and view all the answers

What is the primary function of autoregulation in the cardiovascular system?

<p>To make localised adjustments to blood flow within capillary beds. (B)</p> Signup and view all the answers

If autoregulation fails, what mechanisms are activated in the short term to compensate and control cardiovascular function?

<p>Neural or endocrine mechanisms. (C)</p> Signup and view all the answers

Which of the following best describes the myogenic response?

<p>The response of smooth muscle tissue to pressure changes. (C)</p> Signup and view all the answers

What effect does warming of tissue typically have on local blood vessels?

<p>Vasodilation. (A)</p> Signup and view all the answers

Which of the following is an example of a potent LOCAL vasodilator?

<p>Low pH levels. (C)</p> Signup and view all the answers

What would be a consequence of failure to compensate in response to a loss of blood?

<p>Inadequate blood flow to tissues. (C)</p> Signup and view all the answers

What is the immediate effect of Epinephrine and Norepinephrine (E and NE) on peripheral blood vessels?

<p>Vasoconstriction in the skin and abdominal organs, and vasodilation in skeletal muscle and coronary arteries (C)</p> Signup and view all the answers

Which of the following is NOT monitored by the chemoreceptors in the carotid and aortic bodies?

<p>Blood Glucose concentrations (C)</p> Signup and view all the answers

What is the primary effect of stimulating the carotid sinus?

<p>Decreases heart rate, possibly leading to syncope (A)</p> Signup and view all the answers

Which system is activated in response to a decrease in blood pressure, prompting the release of renin?

<p>The renin-angiotensin-aldosterone system (A)</p> Signup and view all the answers

What would a decrease in blood pressure stimulate in the cardiovascular centers?

<p>Increase in cardiac output and peripheral vasoconstriction (B)</p> Signup and view all the answers

What is the effect of a tight collar or hyperextension of the neck on the carotid sinus?

<p>It may slow heart rate and cause fainting (C)</p> Signup and view all the answers

Which of the following physiological responses is NOT a direct result of chemoreceptor stimulation?

<p>Increased parasympathetic stimulation to the heart (D)</p> Signup and view all the answers

Which of these does NOT contribute to the long-term regulation of blood volume?

<p>Epinephrine (E) (D)</p> Signup and view all the answers

Flashcards

Systolic Blood Pressure

The force exerted by blood on vessel walls during ventricular contraction.

Diastolic Blood Pressure

The force exerted by blood on vessel walls during ventricular relaxation.

Pulse Pressure

The difference between systolic and diastolic pressure.

Mean Arterial Pressure (MAP)

The average pressure in the arteries over a full cardiac cycle.

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Systemic Vascular Resistance (SVR)

The total resistance to blood flow offered by all systemic vasculature.

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Hypertension

High blood pressure, typically above 140/90 mmHg.

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Hypotension

Low blood pressure, typically below 90/60 mmHg.

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Stroke Volume (SV)

The amount of blood ejected from the left ventricle with each heartbeat.

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Blood Pressure

The pressure exerted by the blood against the walls of blood vessels. In clinical settings, it typically refers to the pressure in arteries.

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Cardiac Output

The amount of blood pumped out of the heart per minute.

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Blood Flow

The rate at which blood flows through a particular part of the circulatory system, measured in milliliters per minute.

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Resistance to Flow

The opposition to blood flow through the blood vessels. It's like friction in the system.

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Venous Return

The amount of blood returning to the heart.

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Stroke Volume

The volume of blood pumped out of the heart with each beat.

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Antidiuretic Hormone (ADH)

A hormone released from the pituitary gland that causes water reabsorption in the kidneys, increasing blood volume. It acts as a vasoconstrictor at high concentrations, hence its alternative name, vasopressin.

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Erythropoietin

A hormone released by the kidneys in response to low blood oxygen levels. It stimulates red blood cell production, increasing blood volume and viscosity, ultimately boosting oxygen carrying capacity.

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Atrial Natriuretic Factor (ANF)

A hormone produced by the heart (right atrium) in response to high blood pressure and volume. It reduces blood pressure by promoting sodium and water excretion through the kidneys.

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Brain Natriuretic Peptide (BNP)

A hormone similar to ANF, produced by the heart's ventricles in response to high blood pressure and volume. It lowers blood pressure in a similar way to ANF, reducing the strain on the heart.

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Renin-Angiotensin-Aldosterone System (RAAS)

A group of hormones secreted in response to low blood pressure and volume. They act to increase blood pressure by promoting water and sodium retention in the body.

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What is Systemic Vascular Resistance (SVR)?

The opposition to blood flow in the systemic circulation, largely determined by the diameter of blood vessels. Vasoconstriction increases SVR, leading to higher blood pressure, while vasodilation decreases SVR, lowering blood pressure.

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Autoregulation

The ability of a tissue to automatically adjust its own blood flow to match its metabolic demands.

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What is Poiseuille's Law?

A principle stating that resistance to fluid flow through a tube (like a blood vessel) is inversely proportional to the fourth power of the radius. This means a small decrease in radius leads to a large increase in resistance.

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Intrinsic Control

Local factors that influence blood flow in capillaries, acting independently of the nervous and endocrine systems.

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What is Blood Viscosity?

The thickness of blood, primarily determined by the ratio of red blood cells to plasma volume. A higher viscosity means increased resistance to blood flow. Examples include dehydration and polycythemia.

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Extrinsic control

Neural and endocrine mechanisms that regulate blood pressure and blood flow.

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What is Mean Arterial Pressure (MAP)?

The average pressure in the arteries over a full cardiac cycle. It's calculated as Diastolic Pressure + 1/3 (Pulse Pressure).

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Myogenic response

A local mechanism that causes blood vessels to constrict in response to increased blood pressure and dilate in response to reduced blood pressure.

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What is Pulse Pressure?

The difference between systolic and diastolic blood pressure. It reflects the force of ventricular contraction and the elasticity of the arteries.

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What is Laminar Blood Flow?

The flow of blood in a straight line, where layers slide smoothly past each other without turbulence. It's ideal for efficient blood flow.

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Local vasodilators

Factors that increase local blood flow, such as low O2 or high CO2.

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What is Turbulent Blood Flow?

The flow of blood in a chaotic, swirling pattern that creates resistance and increases the risk of blood clots. It's often caused by obstructions or irregularities in the vessel.

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Local vasoconstrictors

Factors that restrict local blood flow, like high O2 or low CO2.

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Blood flow distribution

The pattern of blood flow within capillary beds, ensuring adequate delivery of oxygen and nutrients and removal of waste.

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What is Darcy's Law for Radial Flow?

An equation that describes the relationship between cardiac output, mean arterial pressure, and total peripheral resistance. It shows that blood flow (CO) is directly proportional to MAP and inversely proportional to TPR.

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Cardiovascular regulation

The coordinated control of cardiovascular function to ensure appropriate blood flow at the right time and in the right area, without drastically altering blood pressure.

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Baroreceptor Reflex

A reflex that helps maintain blood pressure. Baroreceptors in the carotid sinus and aortic arch sense changes in blood pressure and send signals to the cardiovascular center in the brainstem. The cardiovascular center then adjusts heart rate, stroke volume, and peripheral vasoconstriction to maintain a stable blood pressure.

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Chemoreceptor Reflex

A mechanism that regulates blood pressure by detecting changes in blood oxygen, carbon dioxide, and pH levels. Chemoreceptors in the carotid and aortic bodies send signals to the cardiovascular center, influencing heart rate, vasoconstriction, and breathing rate.

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Aldosterone

A hormone released from the adrenal glands that promotes sodium and water reabsorption in the kidneys. This increases blood volume and helps regulate blood pressure.

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