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Questions and Answers
Which of the following is NOT a characteristic of granulocytes?
Which of the following is NOT a characteristic of granulocytes?
A patient with an erythropoietin-secreting tumor would likely exhibit all of the following EXCEPT:
A patient with an erythropoietin-secreting tumor would likely exhibit all of the following EXCEPT:
If a blood sample shows agglutination with anti-A antibodies but not with anti-B antibodies, what is the blood type?
If a blood sample shows agglutination with anti-A antibodies but not with anti-B antibodies, what is the blood type?
Diapedesis is the process by which...
Diapedesis is the process by which...
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Based on the order in the mnemonic, 'Never Let Mom Eat Beans', which of the following white blood cell types is the least numerous in blood?
Based on the order in the mnemonic, 'Never Let Mom Eat Beans', which of the following white blood cell types is the least numerous in blood?
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In an H&E stain, which cellular component would stain pink?
In an H&E stain, which cellular component would stain pink?
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Which of the following characteristics is NOT associated with neutrophils?
Which of the following characteristics is NOT associated with neutrophils?
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What is the primary function of the cytotoxic enzymes released by eosinophils?
What is the primary function of the cytotoxic enzymes released by eosinophils?
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Flashcards
Erythropoietin-secreting tumors
Erythropoietin-secreting tumors
Tumors that increase erythropoietin production, affecting blood parameters.
Hematocrit
Hematocrit
The percentage of blood volume occupied by red blood cells.
Diapedesis
Diapedesis
The process of white blood cells moving in and out of blood capillaries.
Granulocytes
Granulocytes
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Agranulocytes
Agranulocytes
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WBC classes mnemonic
WBC classes mnemonic
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Hemotoxylin & Eosin Staining
Hemotoxylin & Eosin Staining
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Neutrophils
Neutrophils
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Study Notes
Lecture 5 - Even Bloodier!
- Lecture 5 is happening today.
- A quiz will open today and close Monday at 11:00.
- Exam 1 is on Friday, January 31st.
- Complete the material ahead of time.
- Students should have a computer that is working, connected to the internet, and updated.
- Students must bring their own scrap paper if needed.
- Request accommodations at least 5 days in advance.
- Wednesday, January 29th, office hours are extended to 2:00 pm - 3:30 pm.
- Study guide is available on Educat.
Physiological changes in untreated erythropoietin-secreting tumors
- Physiological changes to look for in patients are:
- Increased hematocrit
- Increased oxygen carrying capacity
- Elevated blood viscosity
Blood Typing
- Determining blood types
- Blood typing practice demonstrates procedures and results.
- Specific examples of outcomes (agglutination or no agglutination).
Cells of the Buffy Coat
- Plasma comprises 55% of total blood volume.
- Cellular components account for 45% of total blood volume.
- Buffy coat contains white blood cells and platelets.
- White blood cells (leukocytes) range from 7,000 to 9,000 per mm³.
- Platelets count approximately 250,000 per mm³.
- Red blood cells (RBCs) are approximately 5,000,000 per mm³.
Leukocytes (White Blood Cells)
- Leukocytes (WBCs) range normally from 4,800 to 10,800 cells/µL of blood.
- WBCs are crucial for immune function.
- Excess WBCs could indicate illness.
- Diapedesis is the process where white blood cells move in and out of blood capillaries.
- Granulocytes and agranulocytes are the two categories for white blood cells.
WBC Classes
- Granulocytes:
- Characterized by having granules visible in their cytoplasm.
- Short-lived.
- Function includes numerous actions.
- Agranulocytes:
- Do not exhibit granules in their cytoplasm.
- Longer-lived (some decades).
- Diverse functions, essential in the immune response.
Leukocyte Differentiation
- Neutrophils:
- Multilobed nucleus.
- Important phagocytes, killing bacteria and fungi.
- Contain granules with enzymes for fighting infections.
- Eosinophils:
- Bi-lobed nucleus.
- Key role in fighting parasitic worms.
- Release nitric oxide and cytotoxic enzymes.
- Basophils:
- Very basic staining.
- Contain granules with histamine, contributing to inflammatory response.
- Involved in allergy mechanisms and cancer surveillance.
- Monocytes:
- Large, kidney-shaped nucleus.
- Develop into macrophages, vital phagocytic immune cells.
- Lymphocytes:
- Small size.
- Important for adaptive immunity.
- T-cells and B-cells are subtypes.
"Never Let Mom Eat Beans" Mnemonic
- Mnemonic device to remember white blood cell types (most to least numerous).
- Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils
Cell Staining (Hematoxylin & Eosin)
- Hematoxylin:
- Basic stain.
- Stains the nucleus (DNA) bluish-purple.
- Eosin:
- Acidic stain.
- Stains cytoplasm pink, red, or orange.
Hematopoiesis
- The process by which the body generates all types of blood cells (including WBCs).
- Multipotent hematopoietic stem cells initiate the process.
- The branching pathway and differentiation steps are illustrated.
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Description
Test your knowledge on the physiological changes associated with untreated erythropoietin-secreting tumors and blood typing. This quiz covers key concepts such as hematocrit levels, oxygen carrying capacity, and blood viscosity. Be prepared to answer questions on the procedures and results of blood typing.
