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Physiology of Blood Diseases

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Questions and Answers

What is the primary function of RBCs?

To regulate acid-base balance

To protect against infection and inflammation

To transport oxygen and carbon dioxide to and from body tissues (correct)

To mediate coagulation

What is the term for a decreased number of RBCs in the blood?

Polycythemia

Thrombocytopenia

Anemia (correct)

Leukemia

What is the function of platelets in the blood?

To transport oxygen and carbon dioxide

To interact with plasma and coagulation factors to control bleeding (correct)

To protect against infection and inflammation

To regulate acid-base balance

What is the term for a bleeding disorder characterized by defective haemostasis with abnormal bleeding?

Haemorrhagic diathesis Signup and view all the answers

What is the term for a disorder characterized by a decrease in platelet count?

Thrombocytopenia Signup and view all the answers

What is the term for a disorder characterized by an increase in platelet count?

Thrombocytosis Signup and view all the answers

What is the term for a disorder characterized by abnormal platelet function?

Thrombocytopathy Signup and view all the answers

What are the causes of haemorrhagic diathesis broadly divided into?

Five groups Signup and view all the answers

What is a common characteristic of acute ITP?

It is a self-limited disorder Signup and view all the answers

What is the typical duration of acute ITP?

A few weeks to 6 months Signup and view all the answers

What is the characteristic of vascular bleeding disorders?

Mild bleeding confined to the skin and mucous membranes Signup and view all the answers

What is the normal platelet count in peripheral blood?

Above 150,000/µl Signup and view all the answers

What is the minimum platelet count required for spontaneous haemorrhagic tendency to become clinically evident?

Below 20,000/µl Signup and view all the answers

What is the effect of thrombocytosis on bleeding?

Decreases bleeding Signup and view all the answers

What is the term for bleeding disorders due to vascular abnormalities?

Non-thrombocytopenic purpuras Signup and view all the answers

What is the primary location of bleeding in vascular bleeding disorders?

Skin and mucous membranes Signup and view all the answers

How many main groups of causes are there for thrombocytopenia?

4 Signup and view all the answers