Physiology and Pathogenesis of Rickettsial Infections

Mycoplasma are pleomorphic, 0.2-0.8μm in diameter, facultatively anaerobic, and exhibit a gliding motility pattern.

Mycoplasma have a genome consisting of circular double-stranded DNA, require cholesterol and sterols for membrane synthesis, and exhibit a 'fried-egg' appearance when grown on solid media.

Members of the Mycoplasma family include M.pneumoniae, M.hominis, M.genitalium, and U.urealyticum.

<p>Fever, headache, malaise, skin rash, enlargement of spleen and liver.</p> Signup and view all the answers

<p>Rickettsia are primarily transmitted by arthropod vectors such as ticks, fleas, mites, and lice.</p> Signup and view all the answers

<p>Rickettsia multiply in endothelial cells of small blood vessels, leading to vasculitis, thrombosis, and necrosis. Vascular lesions are prominent in the skin.</p> Signup and view all the answers

<p>Fever, rash, and vasculitis</p> Signup and view all the answers

<p>Rickettsia are transmitted by arthropod vectors and Coxiella is resistant to environmental conditions.</p> Signup and view all the answers

<p>By an active process</p> Signup and view all the answers

<p>Made up of peptidoglycan (contains muramic acid and diaminopimelic acid)</p> Signup and view all the answers

<p>Chlamydiae are not transmitted by arthropods but invade the respiratory system, while Rickettsia are transmitted by arthropods.</p> Signup and view all the answers

<p>Chlamydiae infections can cause trachoma, atypical pneumonia, and genitourinary infections by invading mucous membranes.</p> Signup and view all the answers

<p>By binary fission</p> Signup and view all the answers

<p>32-34 ºC</p> Signup and view all the answers

<p>By arthropods (except for Q fever)</p> Signup and view all the answers