Physiology and Cell Types Overview
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Questions and Answers

Which of the following cell types is responsible for the maintenance of bone?

  • Fat Cells
  • Blood Cells
  • Smooth Muscle Cells
  • Bone Cells (correct)
  • Which of the following is NOT a characteristic of connective tissue?

  • Characterized by extracellular matrix
  • Fills internal spaces
  • Lines external body surface and hollow organs (correct)
  • Most diverse of the four tissues
  • Which organ system is responsible for the breakdown and absorption of food into the body?

  • Lymphatic
  • Cardiovascular
  • Digestive (correct)
  • Skeletal
  • Which of the following is NOT a type of muscle cell?

    <p>Epithelial Muscle Cell (D)</p> Signup and view all the answers

    What is the primary role of the plasma membrane in a cell?

    <p>To control the movement of substances into and out of the cell (C)</p> Signup and view all the answers

    What is the role of the Na+/K+ pump in maintaining resting membrane potential?

    <p>It pumps potassium ions into the cell and sodium ions out of the cell (B)</p> Signup and view all the answers

    What is the correct sequence of events during an action potential?

    <p>Stimulus, depolarization, repolarization, hyperpolarization (C)</p> Signup and view all the answers

    Which type of ion channel is responsible for the rapid depolarization phase of an action potential?

    <p>Voltage-gated Na+ channels (D)</p> Signup and view all the answers

    What is the role of myelin in nerve conduction?

    <p>Myelin increases the speed of nerve conduction (B)</p> Signup and view all the answers

    Which of the following is an example of a positive feedback mechanism?

    <p>Contractions during childbirth (D)</p> Signup and view all the answers

    Which of the following is an example of an excitatory neurotransmitter?

    <p>Acetylcholine (C)</p> Signup and view all the answers

    What is the role of calcium ions in neurotransmitter release?

    <p>Calcium ions trigger the fusion of synaptic vesicles with the presynaptic membrane (B)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of a graded potential?

    <p>They propagate along the entire length of an axon (B)</p> Signup and view all the answers

    Which of the following is an example of a somatic reflex?

    <p>Withdrawal of hand from a hot stove (B)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding the autonomic nervous system?

    <p>The autonomic nervous system regulates functions such as heart rate and digestion (C)</p> Signup and view all the answers

    Which of the following is NOT a function of the nervous system?

    <p>To synthesize hormones (D)</p> Signup and view all the answers

    What type of ion channel is responsible for the opening of chloride channels when GABA binds?

    <p>Ligand-gated (B)</p> Signup and view all the answers

    Which of the following is NOT a function of the central nervous system?

    <p>Control voluntary muscle movement (A)</p> Signup and view all the answers

    What is the main energy source for the central nervous system?

    <p>Glucose (D)</p> Signup and view all the answers

    What is the primary function of the sympathetic nervous system?

    <p>To prepare the body for 'fight-or-flight' response (C)</p> Signup and view all the answers

    Which of the following neurotransmitters is associated with sleep regulation, migraines, appetite, and mood regulation?

    <p>Serotonin (C)</p> Signup and view all the answers

    What is the primary function of the sensory neurons in the nervous system?

    <p>To receive information from the environment (A)</p> Signup and view all the answers

    In the context of neurotransmitter action, what does the term 'excitatory' refer to?

    <p>A neurotransmitter that causes an increase in the likelihood of an action potential occurring (C)</p> Signup and view all the answers

    Which of the following is NOT a type of ion channel found on a cell membrane?

    <p>Potassium-gated (C)</p> Signup and view all the answers

    What is the role of acetylcholine in the neuromuscular junction?

    <p>It is an excitatory neurotransmitter that stimulates muscle contraction (D)</p> Signup and view all the answers

    What is the function of the cerebrospinal fluid?

    <p>To transport nutrients and remove waste products (C)</p> Signup and view all the answers

    Which lobe of the brain is primarily responsible for processing auditory information?

    <p>Temporal (D)</p> Signup and view all the answers

    Which of the following statements is TRUE regarding the blood-brain barrier?

    <p>It is formed by tight junctions between the endothelial cells of capillaries in the brain (A)</p> Signup and view all the answers

    What is the difference between white matter and gray matter in the CNS?

    <p>White matter is primarily composed of myelinated axons, while gray matter is primarily composed of neuron cell bodies and dendrites (C)</p> Signup and view all the answers

    What is the function of the interneurons in the nervous system?

    <p>To connect different neurons within the central nervous system (A)</p> Signup and view all the answers

    What is the role of calcium ions in the process of neurotransmitter release?

    <p>Calcium ions directly stimulate the release of neurotransmitters from the presynaptic neuron (C)</p> Signup and view all the answers

    Flashcards

    Acetylcholine (ACh)

    A neurotransmitter that can be both excitatory or inhibitory depending on receptor type.

    Ion Channels

    Proteins that allow ions to pass through a membrane; includes leakage, voltage-gated, ligand-gated, and mechanically gated.

    Excitatory Neurotransmitter

    Increases the likelihood of action potential in postsynaptic neuron, leading to EPSP.

    Inhibitory Neurotransmitter

    Decreases the likelihood of action potential in postsynaptic neuron, leading to IPSP.

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    Graded Depolarization

    Change in membrane potential that results from neurotransmitter binding, potentially leading to action potential.

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    Acetylcholinesterase (AChE)

    Enzyme that breaks down acetylcholine in the synaptic cleft after its action.

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    Central Nervous System (CNS)

    The part of the nervous system consisting of the brain and spinal cord, responsible for processing information.

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    Blood Brain Barrier

    Protective mechanism that maintains a stable environment for the brain by preventing many substances from entering.

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    Reflex Arc

    A neural pathway that controls a reflex action, automatically responding to stimuli without conscious brain involvement.

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    Dopamine

    A neurotransmitter involved in reward and pleasure systems; can inhibit or excite neuron activity.

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    Somatic Nervous System

    Part of the nervous system responsible for voluntary control of skeletal muscles.

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    Cerebral Cortex

    Outer layer of the brain responsible for higher brain functions, including sensation, communication, and voluntary movement.

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    Functional Areas of Cerebral Cortex

    Includes motor areas (movement control), sensory areas (awareness of sensation), and association areas (information integration).

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    Major Lobes of the Brain

    Includes frontal, parietal, temporal, occipital lobes, and insula; each serves specific functions.

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    Homeostasis

    The maintenance of stable internal conditions despite external changes.

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    Negative Feedback Mechanism

    A process that counteracts a change to return to a set point.

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    Resting Membrane Potential

    The voltage across the plasma membrane when the cell is at rest.

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    Action Potential

    A rapid rise and fall in membrane potential, leading to nerve impulses.

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    Graded Potentials

    Small changes in membrane potential that can lead to action potentials.

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    Neurons

    Cells that transmit signals for communication within the nervous system.

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    Sodium-Potassium Pump

    A mechanism that pumps sodium out and potassium into the cell to maintain resting potential.

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    Myelinated Neurons

    Neurons with a fatty sheath that conducts impulses faster.

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    Synapse

    The junction where communication occurs between two neurons.

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    Chemical Synapses

    Synapses where neurotransmitters are released to transmit signals.

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    Dendrites

    The parts of a neuron that detect stimuli.

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    Epithelial Tissue

    Tissue that covers body surfaces and lines hollow organs.

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    Study Notes

    Physiology

    • Focuses on the functions of the body, often at cellular or molecular levels.
    • Integrated physiology examines how different organ systems work together to maintain homeostasis.
    • Smooth muscle cells are long and slender, found in many organs.
    • Blood cells (red blood cells) are flattened discs or spherical; they transport oxygen and carbon dioxide, while white blood cells fight off infection.
    • Bone cells maintain bone structure, recycling calcium and phosphate.
    • Fat cells store excess energy, enlarging as they accumulate more.
    • Cells clustered together form tissues.
    • Two or more tissues comprise an organ.
    • Two or more organs form an organ system.

    Neurons and Nerve Tissue

    • Transmit signals for communication between cells.
    • Branches receive and transmit messages.
    • Neurons process information.

    Muscle Cells and Epithelium

    • Specialized for contraction.
    • Skeletal muscle cells are involuntary.
    • Smooth muscle cells are involuntary.
    • Cardiac muscle cells are involuntary.

    Epithelial Cells and Epithelium

    • Sheet-like layers of cells.
    • Line external body surfaces and hollow organs.
    • Act as barriers and transport membranes.

    Epithelium Glands

    • Manufacture products, such as saliva and hormones (e.g., from the pituitary or adrenal glands).
    • Exocrine glands produce secretions.
    • Endocrine glands release hormones.

    Connective Tissue

    • Most diverse tissue type.
    • Characterized by an extracellular matrix.
    • Supports and connects different parts of the body.
    • Stores energy.

    Organ Systems

    • Integumentary: Skin protects internal organs.
    • Skeletal: Supports and protects internal organs.
    • Muscular: Movement and generation of heat, excess amino acids.

    Homeostasis

    • Maintain stable internal conditions, despite external fluctuations.
    • Disruption can lead to disease and/or death.
    • Examples: maintaining blood glucose levels at high altitutde, cold or hot climate.

    General Homeostatic Control System

    • Sensor/receptor: Detects changes in a specific variable.
    • Integrator/integrating center: Analyses information and initiates responses.
    • Effector: Muscle or gland that carries out a response.

    Negative Feedback Mechanism

    • A response that reduces or counteracts initial stimulus to prevent overreaction.

    Positive Feedback Mechanism

    • A response enhances the original stimulus to amplify or speed up a process.

    Plasma Membrane

    • Separates intracellular fluid from extracellular fluid.
    • Plays a role in communication, transport, and localization within a cell.

    Permeability

    • Freely permeable: All substances can pass through without difficulty.
    • Selectively permeable: Some substances can pass through; others cannot.
    • Impermeable: No substances can pass through.

    Nervous System Division

    • Autonomic: Involuntary functions (e.g., smooth, cardiac muscle, glands).
    • Somatic: Voluntary functions (e.g., skeletal muscle).
    • Sensory (afferent): Carries signals to the CNS.
    • Motor (efferent): Carries signals to effectors.

    Ions

    • Charged particles (gained or lost electrons).
    • Anions are negatively charged, and cations are positively charged.

    Major Cellular Ions and Membrane Potential

    • Sodium (Na+) is the main extracellular ion.
    • Potassium (K+) is the main intracellular ion.
    • The resting membrane potential (-70mV) involves internal negative charge relative to the outside.

    Ion Passageways Across Membranes

    • Leakage channels (always open)
    • Voltage-gated channels (open/close depending on voltage across the membrane)
    • Ligand-gated channels (open/close in response to a chemical messenger)
    • Mechanically-gated channels(open/close in response to a mechanical event on the cell)

    Resting Membrane Potential

    • Cells have higher intracellular K+ concentration and a high extracellular Na+ concentration.
    • Proteins generally remain inside the cell.

    What is Important About Resting Membrane Potential

    • Propagation of electrical signals through the heart
    • Muscle contraction
    • Secretion of hormones
    • Transmission of nerve impulses.

    Describing Changes in Membrane Potential

    • Normal resting potential near -70 mV.
    • Depolarization: Membrane potential becomes less negative.
    • Hyperpolarization: Membrane potential becomes more negative.
    • Repolarization: Return to resting membrane potential.

    What Causes Changes in Membrane Potential

    • Stimuli trigger changes in the environment of the cell causing ion channels to open and close
    • Ion movement generates graded or action potentials.

    Graded Potentials

    • Small changes in membrane potential.
    • Stronger stimulus creates a larger change.
    • Typically do not reach threshold needed for an action potential.

    Postsynaptic Potential (PSP)

    • Change in membrane potential in a neuron.

    • Excitatory: Increases likelihood of an action potential.

    • Inhibitory: Decreases likelihood of an action potential.

    Threshold and Development of an Action Potential

    • Membrane potential must become less negative and reach a threshold to cause an action potential.

    Action Potential:

    • Specialized channels on the cell membrane open and close depending on voltage
    • Voltage-gated Na+ and K+ channels cause membrane potential to change.

    Action Potential Sequence of Events

    • Stimulus changes the resting membrane potential
    • Voltage-gated Na+ channels open.
    • Membrane potential increases rapidly
    • Na+ channels close and K+ channels open, causing repolarization
    • K+ channels close slowly causing slight hyperpolarization before returning to resting membrane potential.

    Linking Action Potential to Nerves

    • Detection/communication of stimulus between cells.
    • Stimulus → Receptor → Integrating Center → Effector → Response
    • Neurons: Dendrites detect stimuli, the cell body contains the nucleus, and the axon sends action potentials.
    • Myelinated neurons: Whitish coating speeds up action potential transmission.
    • Synapses: Point of communication between neurons.

    Chemical Synapses

    • Neurotransmitters are released across the synapse causing an action potential.
    • Steps: Normal stimulus triggering neurotransmitter release, Calcium ion causes release, ACh binds to receptors on the post synaptic neuron, Depolarization, and ACh breakdown.

    Neurotransmitter Types

    • Excitatory: Increase the likelihood of an action potential.
    • Inhibitory: Decrease the likelihood of an action potential.
    • Different types (e.g., acetylcholine, norepinephrine, dopamine, serotonin, GABA).

    Central Nervous System

    • 15% resting carbon monoxide use
    • 20% of oxygen consumption at rest
    • 50% of resting glucose use
    • Glucose is the main source of energy.
    • Brain is protected by bone, meningeal tissues, and cerebrospinal fluid

    Cerebral Hemispheres

    • Make up 83% of brain mass.
    • Contain ridges and fissures.

    Major Lobes

    • Frontal, Parietal, Temporal, Occipital, Insula

    Cerebral Cortex

    • Enables sensation, communication, memory, and voluntary movements.
    • Hemispheres work contralaterally.

    Functional Areas of Cerebral Cortex

    • Control voluntary movement, sensory awareness.

    Sensory Areas of Note

    • Primary somatosensory cortex, receives sensory information from the skin and skeletal muscle.
    • Somatosensory association cortex processes further sensory information.
    • Visual, auditory, olfactory, and gustatory cortices.

    White and Gray Matter

    • White matter is made up of myelinated neurons.
    • Gray matter is made up primarily of interneurons and cell bodies

    Somatic Nervous System

    • Relates to skeletal muscles, largely under voluntary control.

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    Description

    This quiz covers essential topics in physiology, focusing on the functions and types of cells in the body. It explores the role of different cell types, including smooth muscle, blood cells, bone cells, and neurons, as well as their contributions to organ systems. Test your knowledge of how these cells work together to maintain homeostasis.

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