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Questions and Answers
Which of the following cell types is responsible for the maintenance of bone?
Which of the following cell types is responsible for the maintenance of bone?
Which of the following is NOT a characteristic of connective tissue?
Which of the following is NOT a characteristic of connective tissue?
Which organ system is responsible for the breakdown and absorption of food into the body?
Which organ system is responsible for the breakdown and absorption of food into the body?
Which of the following is NOT a type of muscle cell?
Which of the following is NOT a type of muscle cell?
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What is the primary role of the plasma membrane in a cell?
What is the primary role of the plasma membrane in a cell?
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What is the role of the Na+/K+ pump in maintaining resting membrane potential?
What is the role of the Na+/K+ pump in maintaining resting membrane potential?
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What is the correct sequence of events during an action potential?
What is the correct sequence of events during an action potential?
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Which type of ion channel is responsible for the rapid depolarization phase of an action potential?
Which type of ion channel is responsible for the rapid depolarization phase of an action potential?
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What is the role of myelin in nerve conduction?
What is the role of myelin in nerve conduction?
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Which of the following is an example of a positive feedback mechanism?
Which of the following is an example of a positive feedback mechanism?
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Which of the following is an example of an excitatory neurotransmitter?
Which of the following is an example of an excitatory neurotransmitter?
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What is the role of calcium ions in neurotransmitter release?
What is the role of calcium ions in neurotransmitter release?
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Which of the following is NOT a characteristic of a graded potential?
Which of the following is NOT a characteristic of a graded potential?
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Which of the following is an example of a somatic reflex?
Which of the following is an example of a somatic reflex?
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Which of the following statements is TRUE regarding the autonomic nervous system?
Which of the following statements is TRUE regarding the autonomic nervous system?
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Which of the following is NOT a function of the nervous system?
Which of the following is NOT a function of the nervous system?
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What type of ion channel is responsible for the opening of chloride channels when GABA binds?
What type of ion channel is responsible for the opening of chloride channels when GABA binds?
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Which of the following is NOT a function of the central nervous system?
Which of the following is NOT a function of the central nervous system?
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What is the main energy source for the central nervous system?
What is the main energy source for the central nervous system?
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What is the primary function of the sympathetic nervous system?
What is the primary function of the sympathetic nervous system?
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Which of the following neurotransmitters is associated with sleep regulation, migraines, appetite, and mood regulation?
Which of the following neurotransmitters is associated with sleep regulation, migraines, appetite, and mood regulation?
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What is the primary function of the sensory neurons in the nervous system?
What is the primary function of the sensory neurons in the nervous system?
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In the context of neurotransmitter action, what does the term 'excitatory' refer to?
In the context of neurotransmitter action, what does the term 'excitatory' refer to?
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Which of the following is NOT a type of ion channel found on a cell membrane?
Which of the following is NOT a type of ion channel found on a cell membrane?
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What is the role of acetylcholine in the neuromuscular junction?
What is the role of acetylcholine in the neuromuscular junction?
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What is the function of the cerebrospinal fluid?
What is the function of the cerebrospinal fluid?
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Which lobe of the brain is primarily responsible for processing auditory information?
Which lobe of the brain is primarily responsible for processing auditory information?
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Which of the following statements is TRUE regarding the blood-brain barrier?
Which of the following statements is TRUE regarding the blood-brain barrier?
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What is the difference between white matter and gray matter in the CNS?
What is the difference between white matter and gray matter in the CNS?
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What is the function of the interneurons in the nervous system?
What is the function of the interneurons in the nervous system?
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What is the role of calcium ions in the process of neurotransmitter release?
What is the role of calcium ions in the process of neurotransmitter release?
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Flashcards
Acetylcholine (ACh)
Acetylcholine (ACh)
A neurotransmitter that can be both excitatory or inhibitory depending on receptor type.
Ion Channels
Ion Channels
Proteins that allow ions to pass through a membrane; includes leakage, voltage-gated, ligand-gated, and mechanically gated.
Excitatory Neurotransmitter
Excitatory Neurotransmitter
Increases the likelihood of action potential in postsynaptic neuron, leading to EPSP.
Inhibitory Neurotransmitter
Inhibitory Neurotransmitter
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Graded Depolarization
Graded Depolarization
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Acetylcholinesterase (AChE)
Acetylcholinesterase (AChE)
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Central Nervous System (CNS)
Central Nervous System (CNS)
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Blood Brain Barrier
Blood Brain Barrier
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Reflex Arc
Reflex Arc
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Dopamine
Dopamine
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Somatic Nervous System
Somatic Nervous System
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Cerebral Cortex
Cerebral Cortex
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Functional Areas of Cerebral Cortex
Functional Areas of Cerebral Cortex
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Major Lobes of the Brain
Major Lobes of the Brain
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Homeostasis
Homeostasis
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Negative Feedback Mechanism
Negative Feedback Mechanism
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Resting Membrane Potential
Resting Membrane Potential
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Action Potential
Action Potential
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Graded Potentials
Graded Potentials
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Neurons
Neurons
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Sodium-Potassium Pump
Sodium-Potassium Pump
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Myelinated Neurons
Myelinated Neurons
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Synapse
Synapse
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Chemical Synapses
Chemical Synapses
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Dendrites
Dendrites
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Epithelial Tissue
Epithelial Tissue
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Study Notes
Physiology
- Focuses on the functions of the body, often at cellular or molecular levels.
- Integrated physiology examines how different organ systems work together to maintain homeostasis.
- Smooth muscle cells are long and slender, found in many organs.
- Blood cells (red blood cells) are flattened discs or spherical; they transport oxygen and carbon dioxide, while white blood cells fight off infection.
- Bone cells maintain bone structure, recycling calcium and phosphate.
- Fat cells store excess energy, enlarging as they accumulate more.
- Cells clustered together form tissues.
- Two or more tissues comprise an organ.
- Two or more organs form an organ system.
Neurons and Nerve Tissue
- Transmit signals for communication between cells.
- Branches receive and transmit messages.
- Neurons process information.
Muscle Cells and Epithelium
- Specialized for contraction.
- Skeletal muscle cells are involuntary.
- Smooth muscle cells are involuntary.
- Cardiac muscle cells are involuntary.
Epithelial Cells and Epithelium
- Sheet-like layers of cells.
- Line external body surfaces and hollow organs.
- Act as barriers and transport membranes.
Epithelium Glands
- Manufacture products, such as saliva and hormones (e.g., from the pituitary or adrenal glands).
- Exocrine glands produce secretions.
- Endocrine glands release hormones.
Connective Tissue
- Most diverse tissue type.
- Characterized by an extracellular matrix.
- Supports and connects different parts of the body.
- Stores energy.
Organ Systems
- Integumentary: Skin protects internal organs.
- Skeletal: Supports and protects internal organs.
- Muscular: Movement and generation of heat, excess amino acids.
Homeostasis
- Maintain stable internal conditions, despite external fluctuations.
- Disruption can lead to disease and/or death.
- Examples: maintaining blood glucose levels at high altitutde, cold or hot climate.
General Homeostatic Control System
- Sensor/receptor: Detects changes in a specific variable.
- Integrator/integrating center: Analyses information and initiates responses.
- Effector: Muscle or gland that carries out a response.
Negative Feedback Mechanism
- A response that reduces or counteracts initial stimulus to prevent overreaction.
Positive Feedback Mechanism
- A response enhances the original stimulus to amplify or speed up a process.
Plasma Membrane
- Separates intracellular fluid from extracellular fluid.
- Plays a role in communication, transport, and localization within a cell.
Permeability
- Freely permeable: All substances can pass through without difficulty.
- Selectively permeable: Some substances can pass through; others cannot.
- Impermeable: No substances can pass through.
Nervous System Division
- Autonomic: Involuntary functions (e.g., smooth, cardiac muscle, glands).
- Somatic: Voluntary functions (e.g., skeletal muscle).
- Sensory (afferent): Carries signals to the CNS.
- Motor (efferent): Carries signals to effectors.
Ions
- Charged particles (gained or lost electrons).
- Anions are negatively charged, and cations are positively charged.
Major Cellular Ions and Membrane Potential
- Sodium (Na+) is the main extracellular ion.
- Potassium (K+) is the main intracellular ion.
- The resting membrane potential (-70mV) involves internal negative charge relative to the outside.
Ion Passageways Across Membranes
- Leakage channels (always open)
- Voltage-gated channels (open/close depending on voltage across the membrane)
- Ligand-gated channels (open/close in response to a chemical messenger)
- Mechanically-gated channels(open/close in response to a mechanical event on the cell)
Resting Membrane Potential
- Cells have higher intracellular K+ concentration and a high extracellular Na+ concentration.
- Proteins generally remain inside the cell.
What is Important About Resting Membrane Potential
- Propagation of electrical signals through the heart
- Muscle contraction
- Secretion of hormones
- Transmission of nerve impulses.
Describing Changes in Membrane Potential
- Normal resting potential near -70 mV.
- Depolarization: Membrane potential becomes less negative.
- Hyperpolarization: Membrane potential becomes more negative.
- Repolarization: Return to resting membrane potential.
What Causes Changes in Membrane Potential
- Stimuli trigger changes in the environment of the cell causing ion channels to open and close
- Ion movement generates graded or action potentials.
Graded Potentials
- Small changes in membrane potential.
- Stronger stimulus creates a larger change.
- Typically do not reach threshold needed for an action potential.
Postsynaptic Potential (PSP)
-
Change in membrane potential in a neuron.
-
Excitatory: Increases likelihood of an action potential.
-
Inhibitory: Decreases likelihood of an action potential.
Threshold and Development of an Action Potential
- Membrane potential must become less negative and reach a threshold to cause an action potential.
Action Potential:
- Specialized channels on the cell membrane open and close depending on voltage
- Voltage-gated Na+ and K+ channels cause membrane potential to change.
Action Potential Sequence of Events
- Stimulus changes the resting membrane potential
- Voltage-gated Na+ channels open.
- Membrane potential increases rapidly
- Na+ channels close and K+ channels open, causing repolarization
- K+ channels close slowly causing slight hyperpolarization before returning to resting membrane potential.
Linking Action Potential to Nerves
- Detection/communication of stimulus between cells.
- Stimulus → Receptor → Integrating Center → Effector → Response
- Neurons: Dendrites detect stimuli, the cell body contains the nucleus, and the axon sends action potentials.
- Myelinated neurons: Whitish coating speeds up action potential transmission.
- Synapses: Point of communication between neurons.
Chemical Synapses
- Neurotransmitters are released across the synapse causing an action potential.
- Steps: Normal stimulus triggering neurotransmitter release, Calcium ion causes release, ACh binds to receptors on the post synaptic neuron, Depolarization, and ACh breakdown.
Neurotransmitter Types
- Excitatory: Increase the likelihood of an action potential.
- Inhibitory: Decrease the likelihood of an action potential.
- Different types (e.g., acetylcholine, norepinephrine, dopamine, serotonin, GABA).
Central Nervous System
- 15% resting carbon monoxide use
- 20% of oxygen consumption at rest
- 50% of resting glucose use
- Glucose is the main source of energy.
- Brain is protected by bone, meningeal tissues, and cerebrospinal fluid
Cerebral Hemispheres
- Make up 83% of brain mass.
- Contain ridges and fissures.
Major Lobes
- Frontal, Parietal, Temporal, Occipital, Insula
Cerebral Cortex
- Enables sensation, communication, memory, and voluntary movements.
- Hemispheres work contralaterally.
Functional Areas of Cerebral Cortex
- Control voluntary movement, sensory awareness.
Sensory Areas of Note
- Primary somatosensory cortex, receives sensory information from the skin and skeletal muscle.
- Somatosensory association cortex processes further sensory information.
- Visual, auditory, olfactory, and gustatory cortices.
White and Gray Matter
- White matter is made up of myelinated neurons.
- Gray matter is made up primarily of interneurons and cell bodies
Somatic Nervous System
- Relates to skeletal muscles, largely under voluntary control.
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Description
This quiz covers essential topics in physiology, focusing on the functions and types of cells in the body. It explores the role of different cell types, including smooth muscle, blood cells, bone cells, and neurons, as well as their contributions to organ systems. Test your knowledge of how these cells work together to maintain homeostasis.