32 Questions
What is the main regulatory axis responsible for predictable, regular, and cyclical ovulatory menstrual cycles?
Hypothalamic-Pituitary-Ovarian Axis
Which organ is considered the target of Sex Steroid Hormones in the reproductive process?
Endometrium
What is the approximate rate of depletion of follicles per month until 35 years old?
1000 follicles
What percentage of follicles are ovulated during a woman's entire reproductive life?
More than 99%
Gonadotropin-independent recruitment from primordial follicle until the preantral follicle is the stage of:
gonadotropin-dependent recruitment
Which growth factors are produced by the oocyte and regulate granulosa cell proliferation and differentiation as the primary follicle grows?
Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP-15)
What is the average duration of the menstrual cycle?
28 days
During which phase of the ovarian cycle does ovulation begin?
Follicular or preovulatory phase
What do stromal cells surround as the antral follicle develops?
Thecal cells
Which phase involves endometrial thickening and selection of a dominant "ovulatory" follicle?
Proliferative phase
What is the role of corpus luteum during the luteal or postovulatory phase of the ovarian cycle?
Produce estrogen and progesterone
What is the mechanism of recruitment from primordial follicles to become preantral follicles?
"Gonadotropin-independent" recruitment
"Local growth factors" such as GDF9 and BMP-15 are produced by:
"Oocyte"
"Semisynchronous growth selection window of the ovarian cycle" refers to:
"Dominant follicle" selection process
"FSH increase in the late luteal phase" stimulates:
"FSH receptor increase"
What is responsible for preparing the endometrium for implantation during the luteal or postovulatory phase?
Corpus Luteum
The predictable, regular, and cyclical ovulatory menstrual cycles are regulated by the HYPOTHALAMIC-PITUITARY-OVARIAN AXIS.
True
Malfunctions of the compartments of the HYPOTHALAMIC-PITUITARY-OVARIAN AXIS can lead to reproductive failure or infertility.
True
The rate of depletion of follicles per month is approximately 1,000 until 35 years old.
False
The endometrium is the target organ of Sex Steroid Hormones in the reproductive process.
True
The Primordial Follicle does not need FSH to become Preantral.
True
Growth Differentiation Factor 9 (GDF9) and Bone Morphogenetic Protein 15 (BMP-15) are controlled by the Ovary.
False
Ovulation begins on Day 14 of the menstrual cycle.
True
The average duration of the menstrual cycle is 28 days, with a range of -7 to +7 days.
True
FSH increases in the late luteal phase of the previous cycle.
True
The Dominant Follicle is selected during the Follicular (Preovulatory) Phase.
True
Estrogen increases in proportion to the growth of a Dominant Follicle and its number of Granulosa Cells.
True
The only follicle progressing to a certain stage has the capacity to produce Estrogen.
True
The Ovarian Cycle likely begins 1 to 2 days before Day 1 of the Endometrial Cycle.
True
During each Ovarian Cycle, a group of Antral Follicles 'cohort' begins a phase of semisynchronous growth selection window.
True
"Local growth factors" such as GDF9 and BMP-15 are produced by the Oocyte.
True
"Semisynchronous growth selection window of the ovarian cycle" refers to the stage where only one follicle will be chosen to become the DOMINANT FOLLICLE.
True
Learn about the predictable and spontaneous ovulatory menstrual cycles regulated by the HYPOTHALAMIC-PITUITARY-OVARIAN AXIS (HPO AXIS) and the compartments involved in the process. Explore the intricate interactions of the Hypothalamus, Anterior Pituitary Gland, Ovary, and Endometrium as target organs of Sex Steroid Hormones.
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