20 Questions
What is the normal range for Activated Partial Thromboplastin Time (APTT)?
24-36 seconds
What is the recommended maintenance therapy dose for Aspirin to prevent thrombosis?
325 mg/day
Which drug inhibits the synthesis of Vitamin K dependent factors?
Warfarin
Which drug is a specific monoclonal antibody for the platelet surface receptor IIB/IIIA?
Tirofiban
Which group of drugs is generally utilized in acute thrombotic events and during angioplasty procedures?
Injectable anti-Thrombotics
What is the main use of heparin as an anticoagulant?
Preventing deep venous thrombosis
Which of the following is NOT a cause of abnormal clot formation?
Regular exercise
What is the mechanism of action of heparin?
Activates antithrombin III
Which of the following is a therapeutic application of oral anticoagulants?
Preventing prosthetic valves
Which of the following is a potential side effect of warfarin therapy?
Increased bruising
What is the critical balance that must be maintained in relation to coagulation and clot dissolution?
Balance between coagulation and clot dissolution
What is the specific mechanism of action of Streptokinase, urokinase & Tissue plasminogen activator (t-PA)?
Dissolution of formed clots
What is the main use of Abciximab in medical treatment?
Blocking IIb/IIIa receptors responsible for platelet aggregation
What is the purpose of using Fresh Frozen Plasma in the treatment of excessive anticoagulation?
Replacement of lost fluids and blood
Which drug-food interaction should be avoided when on warfarin therapy?
Consumption of dark green, leafy vegetables high in Vitamin K
What is the main mechanism of action of heparin as an anticoagulant?
Inhibition of thrombin
Which of the following is NOT a potential cause of abnormal clot formation?
Prophylactic antibiotics
What is the most significant difference between heparin and oral anticoagulants in terms of administration?
Route of administration
In what way do neoplastic diseases contribute to abnormal clot formation?
Release of procoagulant substances
What is the primary therapeutic application of oral anticoagulants?
Prevention of deep venous thrombosis (DVT)
Test your knowledge on the basic physiology and pathophysiology of clotting disorders, as well as the pharmacology, therapeutic applications, and side effects of heparin and oral anticoagulants. Also, assess your understanding of drug interactions and the use of antithrombotic and thrombolytic medications.
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