Physical Therapy Pharmacotherapeutics: Anticoagulants & Thrombolytics - Reem Almhasis Objectives
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Questions and Answers

What is the normal range for Activated Partial Thromboplastin Time (APTT)?

  • 6-10 seconds
  • 24-36 seconds (correct)
  • 12-20 seconds
  • 40-50 seconds

What is the recommended maintenance therapy dose for Aspirin to prevent thrombosis?

  • 200 mg/day
  • 500 mg/day
  • 50 mg/day
  • 325 mg/day (correct)

Which drug inhibits the synthesis of Vitamin K dependent factors?

  • Eptifibatide
  • Abciximab
  • Aspirin
  • Warfarin (correct)

Which drug is a specific monoclonal antibody for the platelet surface receptor IIB/IIIA?

<p>Tirofiban (A)</p> Signup and view all the answers

Which group of drugs is generally utilized in acute thrombotic events and during angioplasty procedures?

<p>Injectable anti-Thrombotics (D)</p> Signup and view all the answers

What is the main use of heparin as an anticoagulant?

<p>Preventing deep venous thrombosis (A)</p> Signup and view all the answers

Which of the following is NOT a cause of abnormal clot formation?

<p>Regular exercise (D)</p> Signup and view all the answers

What is the mechanism of action of heparin?

<p>Activates antithrombin III (C)</p> Signup and view all the answers

Which of the following is a therapeutic application of oral anticoagulants?

<p>Preventing prosthetic valves (A)</p> Signup and view all the answers

Which of the following is a potential side effect of warfarin therapy?

<p>Increased bruising (C)</p> Signup and view all the answers

What is the critical balance that must be maintained in relation to coagulation and clot dissolution?

<p>Balance between coagulation and clot dissolution (A)</p> Signup and view all the answers

What is the specific mechanism of action of Streptokinase, urokinase & Tissue plasminogen activator (t-PA)?

<p>Dissolution of formed clots (B)</p> Signup and view all the answers

What is the main use of Abciximab in medical treatment?

<p>Blocking IIb/IIIa receptors responsible for platelet aggregation (D)</p> Signup and view all the answers

What is the purpose of using Fresh Frozen Plasma in the treatment of excessive anticoagulation?

<p>Replacement of lost fluids and blood (B)</p> Signup and view all the answers

Which drug-food interaction should be avoided when on warfarin therapy?

<p>Consumption of dark green, leafy vegetables high in Vitamin K (B)</p> Signup and view all the answers

What is the main mechanism of action of heparin as an anticoagulant?

<p>Inhibition of thrombin (B)</p> Signup and view all the answers

Which of the following is NOT a potential cause of abnormal clot formation?

<p>Prophylactic antibiotics (A)</p> Signup and view all the answers

What is the most significant difference between heparin and oral anticoagulants in terms of administration?

<p>Route of administration (D)</p> Signup and view all the answers

In what way do neoplastic diseases contribute to abnormal clot formation?

<p>Release of procoagulant substances (A)</p> Signup and view all the answers

What is the primary therapeutic application of oral anticoagulants?

<p>Prevention of deep venous thrombosis (DVT) (D)</p> Signup and view all the answers

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