Physical Pharmacy - Lecture 1
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Questions and Answers

Which state of matter has a definite shape and volume?

  • Solid (correct)
  • Plasma
  • Liquid
  • Gas
  • What is the primary property of gases regarding their shape and volume?

  • Indefinite shape and indefinite volume (correct)
  • Definite shape and indefinite volume
  • Indefinite shape and definite volume
  • Definite shape and volume
  • How do the particles in a liquid behave compared to those in a solid?

  • Particles in liquids have moderate proximity and are disordered (correct)
  • Particles in liquids are very close and have a definite shape
  • Particles in liquids are closer and more ordered
  • Particles in liquids are far apart and completely disordered
  • What type of forces holds matter together?

    <p>Chemical or intramolecular forces</p> Signup and view all the answers

    Which of the following best describes the characteristics of solids?

    <p>Definite shape, definite volume, and low compressibility</p> Signup and view all the answers

    Which state of matter is characterized by taking the shape of its container but maintaining a fixed volume?

    <p>Liquid</p> Signup and view all the answers

    What happens to the proximity of particles as matter transitions from solid to gas?

    <p>Particles move farther apart.</p> Signup and view all the answers

    Which property differentiates gas from both solid and liquid states significantly?

    <p>Gas is easily compressible.</p> Signup and view all the answers

    What type of forces exist between molecules in different states of matter?

    <p>Intermolecular forces</p> Signup and view all the answers

    Which statement accurately describes the intermolecular forces in solids?

    <p>They are strong enough to lock molecules in place.</p> Signup and view all the answers

    What is the typical strength range of van der Waals' forces?

    <p>1-10 Kcal/mole</p> Signup and view all the answers

    What happens to the average kinetic energy of gas molecules compared to other states of matter?

    <p>It is much larger than in solids and liquids.</p> Signup and view all the answers

    How much energy is typically required to separate molecules compared to breaking covalent bonds?

    <p>16 kJ/mol</p> Signup and view all the answers

    What leads to the formation of dipoles in asymmetrical molecules?

    <p>Unbalanced distribution of electrons</p> Signup and view all the answers

    What is the relationship between intermolecular forces and temperature?

    <p>Higher temperature decreases the strength of intermolecular forces.</p> Signup and view all the answers

    Which of the following best describes van der Waals' forces?

    <p>They are weak forces caused by fluctuations in electron density.</p> Signup and view all the answers

    What is cohesion?

    <p>The physical force between molecules of the same substance.</p> Signup and view all the answers

    How is a molecule defined in the context of atomic interactions?

    <p>A unit formed by strong attractive forces creating observable properties.</p> Signup and view all the answers

    What characterizes ionic bonding?

    <p>The transfer of electrons resulting in charged ions.</p> Signup and view all the answers

    At equilibrium, what occurs between attractive and repulsive forces?

    <p>Attractive and repulsive forces are equal.</p> Signup and view all the answers

    Which of the following correctly describes covalent bonding?

    <p>Is characterized by the sharing of electrons between non-metal atoms.</p> Signup and view all the answers

    What is a common property of ionic compounds at room temperature?

    <p>They exist as crystalline solids.</p> Signup and view all the answers

    What occurs when attractive forces are strong enough to bind atoms into a molecule?

    <p>A chemical bond is formed.</p> Signup and view all the answers

    Which describes the nature of repulsive forces at the molecular level?

    <p>They raise potential energy and create a barrier.</p> Signup and view all the answers

    What type of Van der Waals force occurs between two permanent dipoles?

    <p>Dipole-dipole</p> Signup and view all the answers

    Which of the following is an example of a scenario where dipole-induced dipole forces occur?

    <p>A polar molecule interacting with a non-polar molecule</p> Signup and view all the answers

    What is the primary characteristic of London dispersion forces?

    <p>They can occur between non-polar molecules.</p> Signup and view all the answers

    Which of the following correctly describes dispersion forces?

    <p>They are the weakest and very short-lived.</p> Signup and view all the answers

    In which scenario do dipole-dipole interactions typically manifest?

    <p>Between two polar molecules.</p> Signup and view all the answers

    Which interaction causes a temporary dipole to form in a non-polar molecule?

    <p>Dipole-induced dipole force</p> Signup and view all the answers

    What distinguishes London dispersion forces from the other types of intermolecular forces?

    <p>They occur due to instantaneous dipoles.</p> Signup and view all the answers

    Which of the following statements is true regarding the types of intermolecular forces?

    <p>Dipole-induced dipole forces involve a temporary dipole in a non-polar molecule.</p> Signup and view all the answers

    Study Notes

    Physical Pharmacy - Lecture 1

    • The lecture is an introduction to physical pharmacy.
    • The syllabus topics will cover:
      • State of matter
      • Thermodynamics
      • Solutions of non-electrolytes
      • Solution of electrolytes
      • Ionic equilibria
      • Buffer & Isotonic solution

    Matter

    • All matter is composed of small particles (atoms, molecules, or ions).
    • Matter exists in three states: solid, liquid, and gas.

    States of Matter

    • Solid: Particles are tightly packed in a regular pattern, vibrate but cannot move past each other. Solids maintain their shape.
    • Liquid: Particles are close together with no regular pattern, flow and can easily move or slide past each other. Liquids take the shape of their containers.
    • Gas: Particles are well separated with no regular pattern, vibrate freely at high speeds. Gases take the shape of their containers.

    Particle Properties

    • Solid: Proximity - close; Energy - little; Order - ordered; Volume - definite; Shape - definite
    • Liquid: Proximity - close; Energy - moderate; Order - disordered; Volume - definite; Shape - indefinite
    • Gas: Proximity - far apart; Energy - a lot; Order - very disordered; Volume - indefinite; Shape - indefinite

    Measuring Matter

    • Volume: Measured using a measuring cup.
    • Mass: Measured using a balance or scale.

    Binding Forces

    • All matter is held together by a force.
    • The force between atoms within a molecule is a chemical, or intramolecular force.
    • The force between molecules is a physical, or intermolecular force.

    Repulsive and Attractive Forces

    • All particles exert both attractive and repulsive forces on each other.
    • If attractive forces are strong, the result is a chemical bond (molecule).
    • If forces are not strong enough to bind into a new unit, it is a non-bonding attraction.
    • Repulsion and attraction forces lead to an equilibrium state.

    Intramolecular Forces

    • Ionic Bonding: Electrostatic force of attraction between positively and negatively charged ions (between non-metals and metals). These are generally crystalline solids. (e.g. NaCl).
    • Covalent Bonding: Sharing of electrons (s and p electrons) between atoms (between non-metals).

    Intermolecular Forces

    • Forces between molecules.
    • The average kinetic energy of gas molecules is larger than the attraction's energy between them.
    • Liquids have stronger intermolecular forces than gases, holding molecules close together.
    • Solids have the strongest intermolecular forces, locking molecules in place.

    Heating Curve

    • Represents the change in temperature of a substance as it is heated.
    • Different phases are seen as it changes from solid to liquid and then to vapor.

    Types of Intermolecular Forces

    • Van der Waals forces:
      • Dipole-Dipole forces (e.g., HCI, CH3F)
      • Dipole-Induced Dipole forces (e.g., polar and non-polar molecules)
      • Dispersion/London forces (e.g., non-polar molecules).

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    Physical Pharmacy Lecture 1 PDF

    Description

    This quiz covers the introduction to physical pharmacy, focusing on the states of matter and fundamental properties of different phases. Explore topics including thermodynamics, solutions of non-electrolytes and electrolytes, ionic equilibria, and buffers. Ideal for students beginning their journey in pharmacy studies.

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