Physical Barriers to Infection
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Questions and Answers

Which mechanism relies on a combination of physical expulsion and innate immune components to protect the respiratory system?

  • Ciliary action combined with mucus secretion traps and eliminates pathogens. (correct)
  • The constant flow of urine prevents pathogen colonization in the lungs.
  • The acidic pH of the respiratory tract denatures inhaled pathogens.
  • Sloughing off of skin cells removes surface-level respiratory pathogens.

In which scenario would the flushing action of bodily fluids be LEAST effective as a defense mechanism?

  • Reduced saliva production due to medication side effects, leading to increased oral bacterial colonization. (correct)
  • Saliva production aiding in the digestion of food particles.
  • Frequent urination to clear a urinary tract infection.
  • Increased tear production in response to an allergen.

How does the sloughing off of skin cells contribute to the body's defense against microbial infections, and what is its primary limitation?

  • It alters the skin's pH, inhibiting microbial growth and reproduction.
  • It physically removes microbes present on the skin's surface but is ineffective against deeper, established infections. (correct)
  • It creates an inhospitable environment due to the release of antimicrobial peptides.
  • It triggers a systemic immune response, alerting the body to potential threats.

Which of the following accurately describes the interrelated function of multiple physical barriers in preventing infection?

<p>The constant shedding of skin cells eliminates surface pathogens, complemented by acidic pH of the skin that inhibits microbial growth, creating a multi-layered defense. (F)</p> Signup and view all the answers

How might a disruption in the integrity of the skin, such as a burn, affect systemic immunity?

<p>It would impair systemic immunity by allowing increased entry of pathogens, potentially overwhelming the immune system. (D)</p> Signup and view all the answers

Flashcards

First Line of Defense

The body's initial mechanism to prevent infections, primarily through intact skin.

Ciliary Action

Movement of tiny hair-like structures in respiratory airways that help clear pathogens.

Flushing Mechanisms

Natural actions like tears, urine, and saliva that help expel pathogens from the body.

Skin Sloughing

The process of shedding dead skin cells, aiding in pathogen removal from the body.

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Sticky Mucus

A substance in respiratory and gastrointestinal tracts that traps and helps eliminate pathogens.

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Study Notes

Physical Barriers to Infection

  • Skin acts as the body's initial defense against pathogens. Its unbroken integrity is crucial.
  • Several non-specific physical barriers exist for defense:
    • Cilia in respiratory airways move mucus with trapped pathogens.
    • Coughing and sneezing expel pathogens.
    • Tears, saliva, and urine flush out microbes.
    • Old skin cells shed, carrying away pathogens.
    • Mucus in respiratory and digestive systems traps pathogens.
    • Acidic pH (low pH) in specific locations inhibits microbial growth.

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Description

Explore the body's physical defenses against infection. Learn about the crucial role of skin integrity, cilia, mucus, and acidic pH in preventing pathogen entry and growth. Understand how these non-specific barriers work to protect the body.

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