Podcast
Questions and Answers
What causes 70% of erectile dysfunction according to the text?
What causes 70% of erectile dysfunction according to the text?
- Arterial dilation
- Disorder or dysfunction of blood vessels (correct)
- Psychological stimuli
- Neurologic event
Which physiological process allows the penis to enlarge and results in an erection?
Which physiological process allows the penis to enlarge and results in an erection?
- Venous compression
- Neurologic events
- Arterial dilation
- Smooth muscle relaxation (correct)
What happens to the veins in the penis during an erection?
What happens to the veins in the penis during an erection?
- They get compressed (correct)
- They relax
- They dilate
- They constrict
What is the main physiological event that triggers a penile erection?
What is the main physiological event that triggers a penile erection?
Which arteries play a role in the physiology of penile erection?
Which arteries play a role in the physiology of penile erection?
What physiological process restricts blood flow out of the penis during an erection?
What physiological process restricts blood flow out of the penis during an erection?
What is the role of cGMP in the process described?
What is the role of cGMP in the process described?
In the context of the text, what effect does a PDE-5 inhibitor have?
In the context of the text, what effect does a PDE-5 inhibitor have?
How does Protein Kinase G affect calcium ions in the endoplasmic reticulum?
How does Protein Kinase G affect calcium ions in the endoplasmic reticulum?
Where is the main tissue localization of PDE5 according to the text?
Where is the main tissue localization of PDE5 according to the text?
What is the mechanism of action of PDE5 inhibitors in treating erectile dysfunction?
What is the mechanism of action of PDE5 inhibitors in treating erectile dysfunction?
How does Protein Kinase G affect smooth muscle relaxation according to the text?
How does Protein Kinase G affect smooth muscle relaxation according to the text?
What is the function of Protein Kinase G on the vascular smooth muscle cell?
What is the function of Protein Kinase G on the vascular smooth muscle cell?
What is the 'Kick In' time for smooth muscle relaxation?
What is the 'Kick In' time for smooth muscle relaxation?
How does food affect the absorption of Tadalafil (Cialis)?
How does food affect the absorption of Tadalafil (Cialis)?
Which enzyme is responsible for metabolizing all PDE5 inhibitors?
Which enzyme is responsible for metabolizing all PDE5 inhibitors?
What effect does Protein Kinase G have on potassium (K+) channels of vascular smooth muscle cells?
What effect does Protein Kinase G have on potassium (K+) channels of vascular smooth muscle cells?
Which PDE5 inhibitor has the shortest duration of action?
Which PDE5 inhibitor has the shortest duration of action?
What is the primary action of acetylcholine (ACh) on vascular endothelial cells?
What is the primary action of acetylcholine (ACh) on vascular endothelial cells?
In which state does smooth muscle relaxation occur in the context of penile vascular function?
In which state does smooth muscle relaxation occur in the context of penile vascular function?
What is the main role of nitric oxide (NO) in vascular smooth muscle relaxation during erection?
What is the main role of nitric oxide (NO) in vascular smooth muscle relaxation during erection?
Which enzyme is commonly referred to as Protein Kinase G (PKG) in the context of penile vascular function?
Which enzyme is commonly referred to as Protein Kinase G (PKG) in the context of penile vascular function?
What is the washout time for Cialis, a PDE5 inhibitor, before its effects diminish?
What is the washout time for Cialis, a PDE5 inhibitor, before its effects diminish?
Which of the following stimuli causes the release of nitric oxide (NO) into the smooth muscle cell during penile vascular function?
Which of the following stimuli causes the release of nitric oxide (NO) into the smooth muscle cell during penile vascular function?
What is the main effect of PDE5 inhibitors?
What is the main effect of PDE5 inhibitors?
Which enzyme degrades cGMP, preventing smooth muscle relaxation?
Which enzyme degrades cGMP, preventing smooth muscle relaxation?
What is the main side effect associated with PDE5 inhibitors?
What is the main side effect associated with PDE5 inhibitors?
What is the severe visual side effect associated with PDE5 inhibitors?
What is the severe visual side effect associated with PDE5 inhibitors?
What condition can occur due to the optic nerve damage from PDE5 inhibitors?
What condition can occur due to the optic nerve damage from PDE5 inhibitors?
What should be avoided after taking Tadalafil, Sildenafil, or Vardenafil?
What should be avoided after taking Tadalafil, Sildenafil, or Vardenafil?
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