18 Questions
What is the main function of Phospholipase A2 in lipid digestion?
Removes one fatty acid from carbon 2 of a phospholipid
Which hormone stimulates the gallbladder to contract and release bile during lipid digestion?
Cholecystokinin (CCK)
Which component is NOT typically found in bile?
Amylase
What is the primary function of CCK hormone in lipid digestion?
Stimulate the release of digestive enzymes from the pancreas
Which part of the small intestine primarily produces cholecystokinin (CCK)?
Lower duodenum and jejunum
What is the main role of secretin in lipid digestion?
Stimulate the pancreas and liver to release bicarbonate
What is the main role of lingual and gastric lipases in patients with a near or complete absence of pancreatic lipase?
Break down TAG molecules
Why is emulsification necessary for the digestion of fats?
To enhance enzyme access by increasing surface area
Which two mechanisms are responsible for emulsification in the small intestine?
Bile Salts and Peristalsis
What is the primary function of bile salts in the emulsification process?
Increase the surface area of lipid droplets
What role does peristalsis play in digestion?
Move food along the digestive tract
Which type of enzymes are responsible for degrading dietary TAG, cholesteryl esters, and phospholipids?
Pancreatic Enzymes
What is the primary role of pancreatic lipase in lipid degradation?
Breaking down TAG molecules into monoacylglycerol and free fatty acids
Why is colipase essential for the activity of pancreatic lipase in lipid digestion?
It binds and anchors lipase at the lipid-aqueous interface.
Which enzyme is responsible for hydrolyzing cholesteryl esters during lipid degradation?
Cholesteryl ester hydrolase
What is the function of bile salts in lipid digestion?
Enhancing cholesteryl ester degradation
How does Orlistat, an antiobesity drug, affect fat absorption in the body?
Inhibits gastric and pancreatic lipases
What role does trypsin play in lipid digestion?
Activating procolipase to colipase
This quiz covers the degradation process of phospholipids by Phospholipase A2 in the presence of pancreatic juice, resulting in the formation of lysophospholipids. It also explores the hormonal control of lipid digestion in the small intestine by pancreatic secretions. Test your knowledge on these topics!
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