Phosphofructokinase Activation by F2,6-BP Quiz

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Which pathway is responsible for converting galactose to glucose?

Glycolytic pathway

Leloir pathway (correct)

Gluconeogenesis

Pentose phosphate pathway

In which tissue is fructose primarily metabolized in an unregulated process?

Kidneys

Adipose tissue

Liver (correct)

Muscle

Which enzyme converts fructose-1-P to glyceraldehyde in the liver?

Hexokinase

Glycerol kinase

Aldolase B (correct)

Triose kinase

What process circumvents the PFK reaction during fructose degradation?

Leloir pathway Signup and view all the answers

Which aldolase is unique to the liver and converts fructose-1-P to glyceraldehyde?

Aldolase B Signup and view all the answers

What enzyme is responsible for converting glycerol to glycerol-3-P?

Glycerol kinase Signup and view all the answers

Which of the following can enter the glycolytic pathway via hexokinase ahead of the phosphofructokinase reaction?

Mannose and galactose Signup and view all the answers

What is converted to dihydroxyacetone phosphate by the action of glycerol phosphate dehydrogenase?

Glycerol-3-phosphate Signup and view all the answers

Describe the fate of dietary fructose in the liver compared to glucose in terms of glycolytic metabolism.

Dietary fructose is degraded almost exclusively in the liver in an unregulated process that circumvents the PFK reaction, while glucose follows the conventional glycolytic pathway. Signup and view all the answers

Explain how galactose is converted to glucose through the Leloir pathway.

Galactose is converted to glucose via the Leloir pathway by a series of enzymatic reactions. Signup and view all the answers

How does glycerol enter glycolysis and what are the steps involved in its conversion to dihydroxyacetone phosphate?

Glycerol enters glycolysis by being converted to glycerol-3-P by glycerol kinase. Glycerol-3-P is then oxidized to dihydroxyacetone phosphate by glycerol phosphate dehydrogenase. Signup and view all the answers

How do cells regulate glycolysis through the inhibition of specific enzymes, and what is the consequence of inhibiting these enzymes?

Cells regulate glycolysis by inhibiting hexokinase, phosphofructokinase, and pyruvate kinase. The consequence of inhibiting these enzymes is halting glycolysis. Signup and view all the answers

What are the metabolic fates of pyruvate produced in glycolysis and under what conditions do these fates occur?

Pyruvate can be converted to lactate or acetyl-CoA. The conversion to lactate occurs under anaerobic conditions, while the conversion to acetyl-CoA occurs under aerobic conditions. Signup and view all the answers

How do cells respond to hypoxic stress in terms of glycolysis, and what adaptations are made to maintain ATP production?

During hypoxic stress, cells increase glycolysis to produce ATP anaerobically. This allows cells to continue generating ATP in the absence of oxygen. Signup and view all the answers

What are the metabolic fates of NADH and pyruvate produced in glycolysis?

The metabolic fates of NADH and pyruvate produced in glycolysis include proceeding through the TCA cycle in aerobic conditions or being converted to lactate in microorganisms and animals. Signup and view all the answers

How do cells respond to hypoxic stress?

Cells respond to hypoxic stress by upregulating glycolysis as an alternative pathway for ATP production in the absence of oxygen. Signup and view all the answers

Are substrates other than glucose used in glycolysis?

Yes, substrates other than glucose can be used in glycolysis. For example, fructose and galactose can enter the glycolytic pathway. Signup and view all the answers

What are the essential features of glycolysis?

The essential features of glycolysis include the conversion of glucose into pyruvate, ATP generation, and the production of NADH. Signup and view all the answers

Phosphofructokinase Activation by F2,6-BP Quiz

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