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Questions and Answers
During high-intensity exercise, which of the following reactions is catalyzed by creatine kinase (CK)?
During high-intensity exercise, which of the following reactions is catalyzed by creatine kinase (CK)?
- The transfer of a phosphate from ADP to creatine to form phosphocreatine.
- The transfer of a phosphate from phosphocreatine to ADP to form ATP. (correct)
- The synthesis of phosphocreatine from creatine and phosphate.
- The breakdown of ATP into ADP and phosphate.
What is the primary role of the phosphagen system in the initial stages of exercise?
What is the primary role of the phosphagen system in the initial stages of exercise?
- To rapidly supply ATP for immediate energy needs focusing predominately on low-intensity exercises.
- To rapidly supply ATP for high-intensity activities, bridging the gap until other energy systems become active. (correct)
- To slowly provide a sustained level of ATP production using fatty acids.
- To immediately provide ATP for high-intensity activities using glucose from glycogen.
If muscle cells contain approximately 4-6 times more phosphocreatine (PCr) than ATP, why is ATP still so crucial for immediate energy demands?
If muscle cells contain approximately 4-6 times more phosphocreatine (PCr) than ATP, why is ATP still so crucial for immediate energy demands?
- PCr is more unstable than ATP, making it less readily available during muscle contractions.
- ATP is the direct energy source used in cellular processes whereas PCr must be converted to ATP first via creatine kinase (CK). (correct)
- ATP is the only form of energy that can be utilized by the electron transport chain (ETC).
- PCr is primarily used for long-term, low-intensity activities, and not for short-term energy.
During recovery from exercise, how is phosphocreatine (PCr) resynthesized in muscle cells?
During recovery from exercise, how is phosphocreatine (PCr) resynthesized in muscle cells?
The phosphagen system is most effective for activities lasting up to approximately how long?
The phosphagen system is most effective for activities lasting up to approximately how long?
Following intense exercise, roughly how long does it take for phosphocreatine (PCr) stores to fully recover, assuming ATP recovery has already occurred?
Following intense exercise, roughly how long does it take for phosphocreatine (PCr) stores to fully recover, assuming ATP recovery has already occurred?
Why is the phosphagen system considered the preferred energy source at the start of exercise?
Why is the phosphagen system considered the preferred energy source at the start of exercise?
If the phosphagen system does not recover adequately between exercise bouts, what is a likely consequence?
If the phosphagen system does not recover adequately between exercise bouts, what is a likely consequence?
Flashcards
Stored ATP
Stored ATP
Stored ATP is the primary energy source for short-term, high-intensity activities like sprinting or resistance training. It's utilized at the beginning of all exercise, regardless of intensity. However, cellular ATP stores are limited, lasting only 3-5 seconds at maximal intensity, thus requiring continuous resynthesis.
Phosphocreatine (PCr)
Phosphocreatine (PCr)
Phosphocreatine (PCr) acts as a phosphate donor, rapidly providing ATP for intense physical activity. Cells store considerably more PCr than ATP, around 4-6 times greater, supporting high-intensity effort for about 10 seconds.
Creatine Kinase (CK)
Creatine Kinase (CK)
Creatine Kinase (CK) is an enzyme that facilitates the rapid transfer of phosphate from PCr to ADP, producing ATP. This reaction is reversible, enabling ATP regeneration from PCr during recovery.
ATP recovery (Rest)
ATP recovery (Rest)
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PCr recovery (Rest)
PCr recovery (Rest)
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Phosphagen system
Phosphagen system
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Phosphagen system recovery
Phosphagen system recovery
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Importance of the phosphagen system
Importance of the phosphagen system
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Study Notes
Phosphagen System
- The phosphagen system is the primary energy source for short-term, high-intensity activities like resistance training and sprinting.
- It's active at the start of all exercise regardless of intensity.
- It provides ATP for only 3-5 seconds at maximal intensity.
- Muscles store ~4-6 times more phosphocreatine (PCr) than ATP.
Stored ATP
- Muscle cells contain a small amount of ATP, requiring continuous resynthesis.
- ATP provides the initial burst of energy.
- The stored ATP amount is limited.
Phosphocreatine (PCr)
- Phosphocreatine rapidly provides ATP.
- Creatine kinase (CK) transfers a phosphate from PCr to ADP, creating ATP.
- Muscles store enough PCr for about 10 seconds of maximal intensity.
- PCr stores are replenished during recovery through CK reversing the reaction.
Creatine Kinase (CK)
- CK is a reversible enzyme.
- Active during high-intensity exercise, taking phosphate from PCr to add to ADP.
- Also uses ATP to regenerate PCr during recovery.
Recovery
- Oxidative phosphorylation replenishes ATP stores.
- The electron transport chain (ETC) via ATP synthase generates ATP.
- PCr recovery takes 3-5 minutes.
- Complete phosphagen system recovery takes 8-10 minutes.
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