5 Questions
What is the primary cell type involved in pheochromocytoma?
Chromaffin cells
What is the condition called when the tumor develops outside the adrenal medulla?
Paraganglioma
Which of the following is NOT a common symptom of pheochromocytoma?
Hypotension
Which laboratory test is NOT typically used to diagnose pheochromocytoma?
Cortisol level in the blood
What is the primary biochemical characteristic of pheochromocytoma?
Uncontrolled release of catecholamines
Study Notes
Pheochromocytoma
- Rare tumor of chromaffin cells (pheochromocytes) located in adrenal medulla.
- Tumor developed in chromaffin cells outside adrenal medulla is called paraganglioma.
Symptoms
- Hypertension
- Tachycardia
- Hyperhidrosis (excessive sweating)
Laboratory Diagnosis
- Measurement of catecholamines level in the blood
- Measurement of metanephrine and normetanephrine levels in the blood
- Measurement of Vanillyl Mandelic Acid (VMA) and Homovanillic Acid levels in the urine
A rare tumor of chromaffin cells, featuring uncontrolled catecholamine release, leading to hypertension, tachycardia, and hyperhidrosis. Lab diagnosis involves measuring catecholamine levels and metanephrine.
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