Phenytoin Kinetics Quiz

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What is the recommended administration of Phenytoin to reduce gastric irritation?

Before meals

With a glass of milk

After meals (correct)

On an empty stomach

How is Phenytoin affected by particle shape and size?

It is not affected by particle shape and size

It is only affected by particle size

It is affected by particle shape and size (correct)

It is only affected by particle shape

What is the drug of choice for Digitalis-Induced arrhythmia?

Phenytoin (correct)

Valproic acid

Levetiracetam

Carbamazepine

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Gingival hyperplasia Signup and view all the answers

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

First trimester of pregnancy Signup and view all the answers

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

Slow I.V. Signup and view all the answers

What is the primary site of metabolism of Phenytoin?

Hepatic microsomal enzymes Signup and view all the answers

Which drug is an inducer of hepatic microsomal enzymes (HME) leading to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Phenytoin Signup and view all the answers

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

Phenytoin Signup and view all the answers

Which drug is a prodrug form of phenytoin and has the advantage of less vascular irritation and greater physical compatibility with IV and IM solutions?

Fosphenytoin Signup and view all the answers

Which drug can inhibit the metabolism of phenytoin?

Valproate Signup and view all the answers

Which drug can displace phenytoin from plasma proteins?

Valproate Signup and view all the answers

Which deficiency can occur due to the metabolism of Vitamin K by phenytoin?

Hypoprothrombinemia Signup and view all the answers

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Megaloblastic anemia Signup and view all the answers

What advantage does fosphenytoin have over phenytoin?

Less vascular irritation Signup and view all the answers

What is the recommended administration of Phenytoin to reduce gastric irritation?

After meals Signup and view all the answers

Which adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Gum (Gingival) Hyperplasia Signup and view all the answers

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

First trimester of pregnancy Signup and view all the answers

What is the primary site of metabolism of Vitamin K by phenytoin?

Liver Signup and view all the answers

Which drug is a prodrug form of phenytoin and has the advantage of less vascular irritation and greater physical compatibility with IV and IM solutions?

Fosphenytoin Signup and view all the answers

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

Phenytoin Signup and view all the answers

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Folate deficiency Signup and view all the answers

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Phenytoin Signup and view all the answers

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

Phenytoin Signup and view all the answers

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Gingival hyperplasia Signup and view all the answers

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

Pregnancy Signup and view all the answers

What advantage does fosphenytoin have over phenytoin?

Greater physical compatibility with IV and IM solutions Signup and view all the answers

Which drug can inhibit the metabolism of phenytoin?

Valproate Signup and view all the answers

Which deficiency can occur due to the metabolism of Vitamin K by phenytoin?

Hypoprothrombinemia Signup and view all the answers

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

Intravenous Signup and view all the answers

What is the primary site of metabolism of Phenytoin?

Hepatic microsomal enzymes Signup and view all the answers

Which drug can inhibit the metabolism of phenytoin?

Rifampicin Signup and view all the answers

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

Intravenous Signup and view all the answers

Which deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Vitamin B12 deficiency Signup and view all the answers

What advantage does fosphenytoin have over phenytoin?

Rapid intravenous administration Signup and view all the answers

Which adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Gum (Gingival) Hyperplasia Signup and view all the answers

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Phenobarbital Signup and view all the answers

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of oral contraceptives?

Phenobarbitone Signup and view all the answers

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Megaloblastic anemia Signup and view all the answers

Which drug can displace phenytoin from plasma proteins?

Valproate Signup and view all the answers

What is the primary site of metabolism of Vitamin K by phenytoin?

Liver Signup and view all the answers

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Gingival hyperplasia Signup and view all the answers

What advantage does fosphenytoin have over phenytoin?

Less vascular irritation Signup and view all the answers

Which drug is a hepatic microsomal enzyme (HME) inhibitor that affects the metabolism of phenytoin?

Valproate Signup and view all the answers

What is the prodrug form of phenytoin with the advantage of greater physical compatibility with IV and IM solutions to dilute it?

Fosphenytoin Signup and view all the answers

Phenytoin Kinetics Quiz

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Questions and Answers

What is the recommended administration of Phenytoin to reduce gastric irritation?

How is Phenytoin affected by particle shape and size?

What is the drug of choice for Digitalis-Induced arrhythmia?

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

What is the primary site of metabolism of Phenytoin?

Which drug is an inducer of hepatic microsomal enzymes (HME) leading to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

Which drug is a prodrug form of phenytoin and has the advantage of less vascular irritation and greater physical compatibility with IV and IM solutions?

Which drug can inhibit the metabolism of phenytoin?

Which drug can displace phenytoin from plasma proteins?

Which deficiency can occur due to the metabolism of Vitamin K by phenytoin?

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

What advantage does fosphenytoin have over phenytoin?

What is the recommended administration of Phenytoin to reduce gastric irritation?

Which adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

What is the primary site of metabolism of Vitamin K by phenytoin?

Which drug is a prodrug form of phenytoin and has the advantage of less vascular irritation and greater physical compatibility with IV and IM solutions?

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Which drug can displace Thyroxin and Tricyclic Anti-Depressants from plasma proteins?

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

In which condition can Phenytoin cause teratogenic effects resulting in Fetal Hydantoin Syndrome?

What advantage does fosphenytoin have over phenytoin?

Which drug can inhibit the metabolism of phenytoin?

Which deficiency can occur due to the metabolism of Vitamin K by phenytoin?

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

What is the primary site of metabolism of Phenytoin?

Which drug can inhibit the metabolism of phenytoin?

What is the recommended route of administration for Phenytoin in the treatment of Status Epilepticus?

Which deficiency can occur due to the metabolism of Folic Acid by phenytoin?

What advantage does fosphenytoin have over phenytoin?

Which adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of other anti-epileptic drugs like barbiturates and carbamazepine?

Which drug is an example of a hepatic microsomal enzyme (HME) inducer that can lead to the metabolism of oral contraceptives?

What deficiency can occur due to the metabolism of Folic Acid by phenytoin?

Which drug can displace phenytoin from plasma proteins?

What is the primary site of metabolism of Vitamin K by phenytoin?

What adverse effect of Phenytoin can be irreversible and requires consultation with dentists, especially in children?

What advantage does fosphenytoin have over phenytoin?

Which drug is a hepatic microsomal enzyme (HME) inhibitor that affects the metabolism of phenytoin?

What is the prodrug form of phenytoin with the advantage of greater physical compatibility with IV and IM solutions to dilute it?

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