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What is the drug class of Phentolamine?
What is the drug class of Phentolamine?
Alpha-blocker
What is the mechanism of action (MOA) of Phentolamine?
What is the mechanism of action (MOA) of Phentolamine?
Direct competition
Which of the following are indications for Phentolamine? (Select all that apply)
Which of the following are indications for Phentolamine? (Select all that apply)
Which of the following are contraindications for Phentolamine? (Select all that apply)
Which of the following are contraindications for Phentolamine? (Select all that apply)
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What are the effects of Phentolamine?
What are the effects of Phentolamine?
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Which of the following are adverse effects of Phentolamine? (Select all that apply)
Which of the following are adverse effects of Phentolamine? (Select all that apply)
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What nursing consideration should be taken when administering Phentolamine?
What nursing consideration should be taken when administering Phentolamine?
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Which of the following are drug interactions with Phentolamine? (Select all that apply)
Which of the following are drug interactions with Phentolamine? (Select all that apply)
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Study Notes
Phentolamine
- Class: Alpha-blocker, which inhibits alpha-adrenergic receptors.
Mechanism of Action (MOA)
- Works through direct competition with catecholamines for binding sites on alpha receptors.
Indications
- Utilized in cases of vasopressor extravasation to mitigate tissue damage.
- Effective in the management of hypertension.
Contraindications
- Not recommended for patients with peripheral vascular disease due to potential worsening of blood flow.
- Should be avoided in individuals with hepatic and renal impairment.
- Caution in patients with coronary artery disease.
- Contraindicated in those with gastric ulcers because of potential exacerbation.
- Not suitable for individuals with sepsis, as this can complicate treatment.
Effects
- Leads to peripheral vasodilation, aiding in the reduction of excess vasoconstriction.
- Facilitates restoration of blood flow to ischemic tissues, promoting healing.
Adverse Effects
- First dose phenomenon can occur, resulting in a significant and rapid drop in blood pressure.
- Patients may experience orthostatic hypotension, leading to dizziness upon standing.
- Common side effects include headaches and constipation.
Nursing Considerations
- Continuous monitoring of blood pressure is crucial to avoid complications and ensure patient safety.
Drug Interactions
- Caution when used with beta-blockers, as they can counteract therapeutic effects.
- Alcohol may enhance side effects and lead to increased sedation.
- Concurrent use with erectile dysfunction medications can lead to severe hypotension.
- Care required with epinephrine administration due to risk of profound hypertension.
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Description
Este quiz consiste en fichas de referencia sobre Phentolamine, un bloqueador alfa utilizado en varias condiciones médicas. A través de estas preguntas, aprenderas sobre su mecanismo de acción, indicaciones, contraindicaciones y efectos. Ideal para estudiantes de medicina y farmacología.
