PharmD Clinical Pharmacy PT-124 Physical Pharmacy

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7 Questions

Which statement is true about viscosity?

Viscosity is the resistance of a fluid to flow

What is rheology?

Rheology is the science of the flow and deformation of fluids and solids.

Kinematic viscosity is obtained by dividing the absolute viscosity by the __________ of the liquid.

density

Define fluidity.

Fluidity is the reciprocal of viscosity.

Match the following viscosity units with their corresponding measurement system:

Poise = cgs unit Stoke = cgs unit CentiStoke = cgs unit cps = Viscosity of liquids at 20°C

Explain Newton's law of flow.

Newton's law of flow describes how layers of liquid slide over each other when a force is applied, with velocity directly proportional to distance from the stationary layer.

What is a Newtonian fluid?

A Newtonian fluid is a fluid whose stress versus rate of shear curve is linear and passes through the origin.

Study Notes

Rheology and Viscosity

  • Rheology is the study of the flow of liquids and the deformation of solids, and viscosity is an expression of the resistance of a fluid to flow.
  • The importance of rheology lies in its application in various industries, such as:
    • Pharmaceuticals: affecting the consistency and smoothness of medicinal and cosmetic products.
    • Cosmetics: influencing the texture and feel of products.
    • Food: impacting the texture and consistency of dairy products and other materials.
    • Road building: affecting the flow of materials and their packing into containers.

Newtonian Systems

  • A Newtonian fluid is a fluid whose stress versus rate of shear curve is linear and passes through the origin.
  • The constant of proportionality is known as the viscosity.
  • Examples of Newtonian fluids: water, chloroform, castor oil, and ethyl alcohol.

Newton's Law of Flow

  • The law describes the relationship between the force applied to a fluid and its resulting velocity.
  • The law states that the force per unit area (F'/A) required to bring about flow is proportional to the rate of shear (G).
  • Mathematically, the law can be expressed as: F'/A = η * G, where η is the coefficient of viscosity.

Viscosity

  • Viscosity is a measure of a fluid's resistance to flow.
  • The unit of viscosity is the poise (P), which is defined as the shearing force required to produce a velocity of 1 cm/sec between two parallel planes of liquid each 1cm2 in area and separated by a distance of 1 cm.
  • The cgs units for the poise are dyne.sec/cm² or g/cm.sec.

Fluidity and Kinematic Viscosity

  • Fluidity is the reciprocal of viscosity: φ = 1/η.
  • Kinematic viscosity is obtained by dividing the absolute viscosity by the density of the liquid at a definite temperature: Kinematic viscosity = η/ρ.
  • Units of kinematic viscosity: the stoke (S) and centiStoke (cS).

A quiz for PharmD students at Horus University's Faculty of Pharmacy, covering physical pharmacy concepts as part of the PT-124 course. Test your knowledge of physical pharmacy principles and applications in pharmaceutical technology.

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