Podcast
Questions and Answers
What is a potential physicochemical effect that can impact the solubility of drugs like diazepam?
What is a potential physicochemical effect that can impact the solubility of drugs like diazepam?
- Leaching of phthalates
- Solvent composition in drug formulations (correct)
- Addition of chelating agents
- Exclusion of oxygen during packaging
How can the stability of basic drugs be enhanced according to the text?
How can the stability of basic drugs be enhanced according to the text?
- Adding antioxidants like ascorbic acid
- Increasing exposure to light transmission
- Diluting the drug to a certain ratio (correct)
- Mixing with a higher concentration of propylene glycol
What type of drug formulation issue arises when preparing a diazepam injection with specific solvent compositions?
What type of drug formulation issue arises when preparing a diazepam injection with specific solvent compositions?
- Precipitation depending on concentration (correct)
- Migration of phthalates
- Leaching of inorganic radicals
- Formation of crystalline forms
What is a common method mentioned in the text for minimizing oxidation in pharmaceutical products?
What is a common method mentioned in the text for minimizing oxidation in pharmaceutical products?
What area of pre-formulation is often overlooked, as mentioned in the text?
What area of pre-formulation is often overlooked, as mentioned in the text?
What can be used to remove metal ions from pharmaceutical products?
What can be used to remove metal ions from pharmaceutical products?
How can the stability of basic drugs be increased in acidic conditions according to the text?
How can the stability of basic drugs be increased in acidic conditions according to the text?
What is the purpose of using Butylated hydroxytoluene (BHT) in medicines?
What is the purpose of using Butylated hydroxytoluene (BHT) in medicines?
How does oxidation impact fatty acids?
How does oxidation impact fatty acids?
What is a common consequence of the oxidation of adrenaline?
What is a common consequence of the oxidation of adrenaline?
Why is captopril available only as a solid dosage form?
Why is captopril available only as a solid dosage form?
What do short shelf lives of extemporaneous aqueous preparations imply?
What do short shelf lives of extemporaneous aqueous preparations imply?
How does understanding medicine stability help in patient treatment?
How does understanding medicine stability help in patient treatment?
Which aspect of drug degradation has been the focus in the provided content?
Which aspect of drug degradation has been the focus in the provided content?
What factor can lead to the loss of protection against microbiological spoilage?
What factor can lead to the loss of protection against microbiological spoilage?
Which factor may lead to a change in bioavailability of medicines?
Which factor may lead to a change in bioavailability of medicines?
What characteristic does polymorphic form I have?
What characteristic does polymorphic form I have?
Which medicine may convert to an amorphous form with higher dissolution rate under mechanical stress?
Which medicine may convert to an amorphous form with higher dissolution rate under mechanical stress?
What is the consequence of large particles in suspensions according to Stoke's Law?
What is the consequence of large particles in suspensions according to Stoke's Law?
Which type of emulsion is thermodynamically unstable?
Which type of emulsion is thermodynamically unstable?
'Creaming' is most likely to occur in which type of emulsion?
'Creaming' is most likely to occur in which type of emulsion?
What does 'stability' refer to in the context of medicines?
What does 'stability' refer to in the context of medicines?
Which of the following is NOT a role of a pharmacist in relation to stability of medicines?
Which of the following is NOT a role of a pharmacist in relation to stability of medicines?
What does the term 'bioavailability changes' refer to in the context of medicines?
What does the term 'bioavailability changes' refer to in the context of medicines?
Which aspect is NOT included in a pharmacist's role in maintenance of stability?
Which aspect is NOT included in a pharmacist's role in maintenance of stability?
What are pharmacists required to understand regarding the clinical implications of loss of stability?
What are pharmacists required to understand regarding the clinical implications of loss of stability?
How does the design of stable medicines contribute to their long-term effectiveness?
How does the design of stable medicines contribute to their long-term effectiveness?
Which factor is essential for assessing the long-term stability of medicines?
Which factor is essential for assessing the long-term stability of medicines?
'Maintenance of stability' includes which important activity related to medicine use?
'Maintenance of stability' includes which important activity related to medicine use?
What does 'product stability' encompass as it relates to medicines?
What does 'product stability' encompass as it relates to medicines?
What are the implications of drug degradation that pharmacists should understand?
What are the implications of drug degradation that pharmacists should understand?
Explain the importance of understanding the physical stability of medicines.
Explain the importance of understanding the physical stability of medicines.
How does oxidation impact fatty acids?
How does oxidation impact fatty acids?
What is the role of captopril in pharmaceutical use?
What is the role of captopril in pharmaceutical use?
Why are extemporaneous aqueous preparations known for short shelf lives?
Why are extemporaneous aqueous preparations known for short shelf lives?
