Menthol Eucalyptus Inhalation Quiz & Flashcards

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Questions and Answers

What is the primary mode of administration for inhalation preparations?

Parenteral administration

Aerosol administration (correct)

Oral administration

Topical administration

What is the composition of a two-phase Pressurized Metered Dose Inhaler?

Liquid and solid

Gas and solid

Gas, liquid, and solid

Gas and liquid (correct)

What is the test for Uniformity of delivered dose in Pressurised Metered – Dose Preparation?

9 out of 10 results lie between 60 to 140 % of the average value

9 out of 10 results lie between 90 to 110 % of the average value

9 out of 10 results lie between 75 to 125 % of the average value (correct)

9 out of 10 results lie between 50 to 150 % of the average value

What happens if 2 or 3 values lie outside the limits of 75 – 125 % in the Uniformity of delivered dose test?

The test is repeated for two more inhalers Signup and view all the answers

What is the purpose of the Description test in Pressurised Metered – Dose Preparation?

To comply with the Specification of Products Signup and view all the answers

What is the composition of the aerosol in Pressurized Metered Dose Inhalers?

Dispersion of solid or liquid particles in a gas Signup and view all the answers

What is the main purpose of inhalation preparations?

To treat respiratory conditions Signup and view all the answers

What happens when the active ingredient is volatile at room temperature?

It is placed on an adsorbent pad and inhaled Signup and view all the answers

What is the function of Light Magnesium Carbonate in Menthol & Eucalyptus Inhalation BP 1980?

To act as a diffusing agent Signup and view all the answers

What is the advantage of the inhalation route of drug administration?

It has a lower risk of systemic side effects Signup and view all the answers

What is the typical duration of inhalation of vapour in inhalation preparations?

Five to ten minutes Signup and view all the answers

What is the purpose of grinding menthol to a fine powder in the preparation of Menthol & Eucalyptus Inhalation BP 1980?

To increase the surface area for dissolution Signup and view all the answers

What is the composition of inhalation preparations?

One or more active ingredients dissolved or dispersed in a suitable vehicle Signup and view all the answers

What is the primary function of an aerosol inhalation device?

To deliver a solution or suspension of a medicament as a vapour or aerosol Signup and view all the answers

What is the benefit of the direct delivery of the drug to the site of action in the inhalation route?

It produces a smaller drug dose Signup and view all the answers

What is the name of the type of bottle used to dispense Menthol & Eucalyptus Inhalation BP 1980?

White fluted bottle Signup and view all the answers

What is the definition of an inhalation preparation?

A liquid or solid dosage form intended for administration as vapours or aerosols to the lung Signup and view all the answers

What is the main advantage of using inhalation devices compared to oral administration?

It has a lower risk of side effects Signup and view all the answers

What is the purpose of adding water to the preparation of Menthol & Eucalyptus Inhalation BP 1980?

To create a pourable suspension Signup and view all the answers

What is the effect of inhalation preparations on the respiratory tract?

It relieves congestion Signup and view all the answers

What is the function of the metering valve in an aerosol inhalation device?

To deliver a specific amount of the medicament with each use Signup and view all the answers

What is the vehicle used in Menthol & Eucalyptus Inhalation BP 1980?

Water Signup and view all the answers

Study Notes

Method of Preparation of Menthol & Eucalyptus Inhalation BP 1980

Formula: Menthol 2g, Eucalyptus oil 10ml, Light Magnesium Carbonate 7g, Water to 100ml
Menthol dissolves in Eucalyptus oil, Light MgCO3 acts as a diffusing agent, and Water is a vehicle
Preparation involves grinding Menthol to a fine powder, adding Eucalyptus oil, and then Light MgCO3, followed by gradual addition of Water

Labeling and Container

Dispensed in white fluted bottles
Direction to shake the bottle before use

Aerosol Inhalations

Consists of a solution or suspension of a medicament in a mixture of inert propellants held under pressure in an aerosol dispenser
Consists of a suitable container fitted with a special metering valve

Definition of Inhalation Preparations

Liquid or solid dosage forms intended for administration as vapors or aerosols to the lung to obtain a local or systemic effect
Contain solution or dispersion of one or more active ingredients in a suitable vehicle
Can be administered as aerosol (dispersion of solid or liquid particles in a gas) using pressurized metered-dose inhalers or powder inhalers

Pressurized Metered Dose Inhalers

Two types: Two-phase system (gas and liquid) and Three-phase system (gas, liquid, and solid or liquids)
Dosage form containing therapeutically active ingredients packed under pressure in a sealed container and released as a fine mist of spray upon actuation

Standard Tests or Evaluation

Description: Should comply with specification of products
Content of active ingredient delivered per actuation: Should comply with the specification
Uniformity of delivered dose: Should comply with the test, with 9 out of 10 results lying between 75% and 125% of the average value and all lying between 65% and 135%

Inhalation Preparations

Liquid preparations composed of or containing volatile substances which, when vaporized, are intended to be brought into contact with the lining of the respiratory tract
Used to relieve congestion and inflammation of the respiratory tract
Can be administered by placing the active ingredient on an adsorbent pad and inhaling from it, or by adding it to water at about 65°C and inhaling the vapor for 5-10 minutes

The Inhalation Route of Drug Administration

To produce either local or systemic effect
Mainly used to treat respiratory conditions like asthma
Onset of drug action is seen immediately as the drug can be delivered directly to the site of action (lungs)
Smaller drug dose is required to produce the desired effect than oral route
Risk of systemic side effects is reduced

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Description

This quiz covers the preparation and labeling of Menthol & Eucalyptus Inhalation BP 1980, including its formula and ingredients.

Pharmacy Preparation: Menthol & Eucalyptus Inhalation BP 1980

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