Pharmacy Preparation: Menthol & Eucalyptus Inhalation BP 1980

Method of Preparation of Menthol & Eucalyptus Inhalation BP 1980

• Formula: Menthol 2g, Eucalyptus oil 10ml, Light Magnesium Carbonate 7g, Water to 100ml
• Menthol dissolves in Eucalyptus oil, Light MgCO3 acts as a diffusing agent, and Water is a vehicle
• Preparation involves grinding Menthol to a fine powder, adding Eucalyptus oil, and then Light MgCO3, followed by gradual addition of Water

Labeling and Container

• Dispensed in white fluted bottles
• Direction to shake the bottle before use

Aerosol Inhalations

• Consists of a solution or suspension of a medicament in a mixture of inert propellants held under pressure in an aerosol dispenser
• Consists of a suitable container fitted with a special metering valve

Definition of Inhalation Preparations

• Liquid or solid dosage forms intended for administration as vapors or aerosols to the lung to obtain a local or systemic effect
• Contain solution or dispersion of one or more active ingredients in a suitable vehicle
• Can be administered as aerosol (dispersion of solid or liquid particles in a gas) using pressurized metered-dose inhalers or powder inhalers

Pressurized Metered Dose Inhalers

• Two types: Two-phase system (gas and liquid) and Three-phase system (gas, liquid, and solid or liquids)
• Dosage form containing therapeutically active ingredients packed under pressure in a sealed container and released as a fine mist of spray upon actuation

Standard Tests or Evaluation

• Description: Should comply with specification of products
• Content of active ingredient delivered per actuation: Should comply with the specification
• Uniformity of delivered dose: Should comply with the test, with 9 out of 10 results lying between 75% and 125% of the average value and all lying between 65% and 135%

Inhalation Preparations

• Liquid preparations composed of or containing volatile substances which, when vaporized, are intended to be brought into contact with the lining of the respiratory tract
• Used to relieve congestion and inflammation of the respiratory tract
• Can be administered by placing the active ingredient on an adsorbent pad and inhaling from it, or by adding it to water at about 65°C and inhaling the vapor for 5-10 minutes

The Inhalation Route of Drug Administration

• To produce either local or systemic effect
• Mainly used to treat respiratory conditions like asthma
• Onset of drug action is seen immediately as the drug can be delivered directly to the site of action (lungs)
• Smaller drug dose is required to produce the desired effect than oral route
• Risk of systemic side effects is reduced

This quiz covers the preparation and labeling of Menthol & Eucalyptus Inhalation BP 1980, including its formula and ingredients.