Pharmacy Orientation (PIP 111) - Lecture 4
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What role did apothecaries serve in the early development of pharmacy?

  • They primarily provided medical advice to patients.
  • They conducted industrial research on new drugs.
  • They prepared and sold drugs for medicinal purposes. (correct)
  • They mainly prescribed medicine without any formal training.
  • What major change occurred in the role of apothecaries by 1811?

  • They were replaced by physicians in drug compounding.
  • They no longer had authority to write prescriptions.
  • They became full-time pharmaceutical practitioners. (correct)
  • They began to receive formal education.
  • Which significant publication was introduced in 1820 to guide drug use in the United States?

  • Pharmacopoeia of the United States (correct)
  • The Pharmacy Handbook
  • The American Medical Journal
  • The Drug Compendium
  • What is counter-prescribing in the context of American pharmacy?

    <p>Apothecaries writing prescriptions without physician authorization.</p> Signup and view all the answers

    How did the role of pharmacy change in healthcare during the transition to a modern profession?

    <p>Pharmacy solidified its role in dispensing medications.</p> Signup and view all the answers

    What types of new agents were developed through industrial research during the transition to modern pharmacy?

    <p>Analgesics and sedatives.</p> Signup and view all the answers

    What was a notable feature of pharmacy education during the transition to a modern profession?

    <p>Focus on chemical compatibility of ingredients in prescriptions.</p> Signup and view all the answers

    What overall change characterized the 20th century for medical care, including pharmacy?

    <p>A dramatic transformation occurred in practices and roles.</p> Signup and view all the answers

    What was the percentage of prescriptions requiring compounding by a pharmacist in the 1930s?

    <p>75%</p> Signup and view all the answers

    Which of the following statements best describes the change in pharmaceutical practices from the 1930s to the 1970s?

    <p>The need for compounding decreased sharply.</p> Signup and view all the answers

    Which of the following medical advancements began to emerge significantly after World War II?

    <p>High technology in medicine production</p> Signup and view all the answers

    What belief contributed to the use of tea for inducing sweating in Ancient Chinese Medicine?

    <p>Poisonous substances can be expelled through sweat.</p> Signup and view all the answers

    What mixture of ingredients was used in the tea that induced sweating according to Ancient Chinese Medicine?

    <p>Cinnamon, ginger, and honey</p> Signup and view all the answers

    What material was initially used to make the first acupuncture needles?

    <p>Stone</p> Signup and view all the answers

    Which of the following is NOT one of the four categories of doctors in Ancient Chinese Medicine?

    <p>Pharmacist</p> Signup and view all the answers

    Which of the following best describes the shift in medication forms in the 1900s?

    <p>Physicians started using ready-made, single-entity medicines.</p> Signup and view all the answers

    What was one of the first sources of drugs in ancient India?

    <p>Vegetable, animal, and mineral origin</p> Signup and view all the answers

    Which significant event took place in Indian pharmacy around the 1870s?

    <p>Organization of the first class of chemist and druggist</p> Signup and view all the answers

    How does traditional Japanese medicine incorporate treatments?

    <p>Use of acupuncture and herbal medicines</p> Signup and view all the answers

    What was the role of herbal juices in ancient Indian medicine?

    <p>To heal various diseases and injuries</p> Signup and view all the answers

    Which medicinal plant was noted for its anti-inflammatory properties in traditional Indian medicine?

    <p>Curcumin</p> Signup and view all the answers

    When was the first edition of the Japanese Pharmacopoeia published?

    <p>1886</p> Signup and view all the answers

    What significant pharmaceutical company was established in India in 1930?

    <p>Bengal Chemicals and Pharmaceuticals</p> Signup and view all the answers

    Which of the following is a key ingredient used in Japanese traditional medicine for treating headaches and fever?

    <p>Cinnamon with liquorice and ginger</p> Signup and view all the answers

    What was one of the health benefits attributed to Japanese Ginseng?

    <p>Increases energy levels</p> Signup and view all the answers

    Which term began to be widely applied to those interested in organic chemistry by the mid-19th century?

    <p>Pharmaceutical chemist</p> Signup and view all the answers

    What significant publication was released in Florence, Italy, in 1499?

    <p>Guild pharmacopoeia</p> Signup and view all the answers

    What type of products did the Santa Maria Novella Pharmacy eventually expand into?

    <p>Beauty products</p> Signup and view all the answers

    What does the Bowl of Hygeia symbolize?

    <p>Wisdom and healing</p> Signup and view all the answers

    In which century did Apothecaries first emerge as a profession in England?

    <p>16th and 17th century</p> Signup and view all the answers

    What was a common use for Ginseng in Japan aside from increasing energy levels?

    <p>Antidiabetic</p> Signup and view all the answers

    Which goddess is associated with the Bowl of Hygeia?

    <p>Hygeia</p> Signup and view all the answers

    What does the serpent around a palm tree symbolize in pharmacy?

    <p>The connection between the vegetable kingdom and the animal kingdom</p> Signup and view all the answers

    What does the unicorn symbolize in pharmaceutical branding?

    <p>Purity and healing powers against poisons</p> Signup and view all the answers

    Which symbol is commonly used in Europe as a pharmacy shop sign and consists of two tools?

    <p>The mortar and pestle</p> Signup and view all the answers

    What was the original color of the cross that the green cross adopted?

    <p>Red</p> Signup and view all the answers

    What is one interpretation of the origins of the Rx symbol?

    <p>Derived from the ancient Egyptian eye symbol, Eye of Horus</p> Signup and view all the answers

    Which pharmaceutical symbol is associated with the Greek messenger god?

    <p>The caduceus</p> Signup and view all the answers

    What might the choice of green for the pharmacy cross relate to?

    <p>Vegetarian origins of many medications</p> Signup and view all the answers

    Why was the serpent historically associated with healing in pharmacy?

    <p>Their venom is considered beneficial for antidotes</p> Signup and view all the answers

    What does the Rx symbol traditionally signify in pharmacy?

    <p>A directive to take medication</p> Signup and view all the answers

    What historical event is described as the biggest man-made medical disaster?

    <p>The use of thalidomide in treating morning sickness</p> Signup and view all the answers

    Which of the following defects was NOT commonly associated with thalidomide exposure?

    <p>Vision impairments</p> Signup and view all the answers

    What regulatory change occurred after the thalidomide tragedy?

    <p>Mandatory evaluations of drug safety for women</p> Signup and view all the answers

    What common pharmaceutical tool is symbolized alongside the Rx?

    <p>Mortar and pestle</p> Signup and view all the answers

    When was thalidomide first marketed in the United Kingdom?

    <p>1958</p> Signup and view all the answers

    What was thalidomide initially prescribed for?

    <p>Morning sickness in pregnant women</p> Signup and view all the answers

    What did the name 'Grippex' refer to in the context of thalidomide?

    <p>A combination treatment for colds</p> Signup and view all the answers

    Study Notes

    Pharmacy Orientation (PIP 111) - Lecture 4: History of Pharmacy (Continue)

    • Learning Outcomes:
      • Understand the development of the pharmacy profession across different historical periods.
      • Identify common symbols used in pharmacy.
      • Recognize a historical pharmacy mistake and the subsequent corrective action.

    American Pharmacy

    • Apothecary: A person who prepares and sells medicines/drugs (nowadays called a pharmacist).
    • 1811: Apothecaries at New York hospitals became full-time pharmaceutical practitioners responsible for compounding medicines; before this, physicians did this work.
    • 1820: The United States Pharmacopeia (USP) was published as a guide to drugs.
    • 1821: First pharmacy school established in Philadelphia, USA.
    • Counter-prescribing: A practice where apothecaries wrote prescriptions without physician authorization.
      • This led to competition between physicians and pharmacists.
      • Pharmacists believed physician dispensing was the root of their problems.
      • Physicians complained about counter-prescribing.
    • Clearer Boundaries: Later, boundaries between apothecaries and physicians became clearer.

    Transition to a Modern Profession

    • Declining Physician Dispensing: Pharmacy's role in healthcare became more solidified, with physicians dispensing medicines less.
    • New Drugs/Agents: Industrial research created new drugs like aspirin (analgesic/antipyretic) and chloral hydrate (sedative).
    • Pharmacies as Outlets: Pharmacies became outlets for antitoxins and vaccines.
    • Emphasis on Chemical Compatibility: Pharmacy courses transitioned from identifying crude plant drugs to focusing on the chemical compatibility of prescription ingredients.

    The 20th Century

    • Dramatic Change: The 20th century saw a major shift in healthcare, including pharmacy.
    • New Drug Production: The production of antibiotics, antidepressants, antihypertensives, and oral contraceptives began.
    • Specialized Pharmacy: Pharmacy practices specialized further, focusing on preventing and treating serious diseases, moving beyond just curing minor illnesses.
    • High Technology: Post-WWII, American pharmaceutical firms used advanced technology for medicine production, becoming global leaders.
    • Production Changes: Prescriptions requiring compounding by pharmacists dramatically reduced during the 20th century.
      • 1930s: ~75% Rx required compounding.
      • 1950s: ~25% requiring compounding.
      • 1960s: ~4% requiring compounding.
      • 1970s: ~1% requiring compounding.

    Ancient Chinese Medicine

    • Long History: Chinese herbal remedies have existed for 3,000+ years.
    • Categorized Doctors: Physicians were categorized as dieticians, physicians, surgeons, and veterinarians.
    • Sweating/Detoxification: Chinese medicine believed substances could leave the body through opened pores, using tea for inducing sweating.
    • Tea Mixture: These teas were made from cinnamon, ginger, herbs, and honey for flavor.
    • Cinnamon/Ginger Benefits: Cinnamon increased blood circulation (for sweating) and ginger was a carminative.

    Ancient Chinese Medicine (Continued)

    • Acupuncture: Besides herbal remedies, Chinese medicine utilized acupuncture (inserting needles at specific body points).
    • Needle Materials: Needles were initially made from stone, and later from bamboo, metals (bronze, silver, gold, platinum, stainless steel, silicon).
    • Needle Types: Nine main types of needles (cylindrical, flat, round, triangular, lanceolate, and different in end shapes).

    Indian Medicine

    • Ancient Origins: Indian pharmacy dates back over 5,000 years.
    • Natural Sources: Drugs originated from vegetable, animal, and mineral sources.
    • Secret Knowledge: Knowledge of medical systems was often kept within families.
    • Herbal Remedies: Herbal juices were used to treat various diseases and injuries.
    • 1811: The first chemist shop in India was established.

    Indian Medicine (Continued)

    • Pharmacology as a Branch: Pharmacy as a formal field of education began in India in the 1870s, first at Madras Medical College.
    • 1930s: Bengal Chemicals and Pharmaceuticals, an early, large-scale pharmaceutical company, was formed which remains a major company today
    • Pharmacopeia: The first Indian Pharmacopoeia was published in 1955.

    Indian Medicine - Used Natural Agents

    • Curcumin (Turmeric): Anti-inflammatory property
    • Piper nigrum (Black Pepper): Analgesic, anti-inflammatory, anti-diarrheal, and antispasmodic actions
    • Ginger: Anti-inflammatory properties; treatment of nausea and vomiting

    Japanese Medicine

    • Religious Roots: Treatment and prevention were deeply rooted in religious practices.
    • 1886: Japanese Pharmacopoeia was first published.
    • Combined Therapies: Traditional Japanese Medicine (TJM) integrated both acupuncture and herbal remedies.
    • Examples: Germanium (anti-diarrhea), Cinnamon, licorice, and ginger for headaches/fever
    • Ginseng: Energy booster, treated gastrointestinal issues, managed diabetes, anti-ulcer, and hypertension

    The Evolution of Pharmacy and Apothecaries in England

    • Apothecaries (16th-17th Centuries): These individuals prepared and sold medicines/drugs.
    • Chemist and Druggist (Late 18th-19th Centuries): The terms for apothecaries transitioned to chemists and druggists, representing both chemical and drug merchants. These groups also practiced pharmacy.
    • 19th Century Shift: "Pharmaceutical chemist" became more common, reflecting growing knowledge of organic chemistry and compounding.

    Video About the Apothecary

    • The provided URL links to a video about the history of apothecaries in the 17th and 18th centuries

    The Evolution of Pharmacy and Apothecaries in Italy

    • 1499: A Guild pharmacopoeia was published in Florence.
    • 1221: Santa Maria Novella Pharmacy established; the oldest pharmacy in the world.
    • Botanical Gardens: The pharmacy area utilized botanical gardens as a source of herbs, plants, and spices for creating remedies.
    • Profitable Industry Expansion: The industry expanded into the production of beauty products, like perfumes.

    Common Symbols Used in Pharmacy

    • Bowl of Hygeia: The snake coiled around a bowl is a Greek symbol for health, healing, immortality, and wisdom.
    • Caduceus: The staff with two snakes and wings, representing the Greek messenger god Hermes.
    • Serpent around a Palm Tree: A symbol frequently used by French and Portuguese pharmaceutical bodies, relating the snake to healing and the palm tree to vegetable-based remedies.
    • Unicorn: A symbol representing purity, used for healing purposes, often against poisons.
    • Mortar and Pestle: Used as a pharmacy shop sign in Britain and Scotland. Associated with traditional pharmacy practices.
    • Green Cross: Derived from the Red Cross organization; it likely represents the vegetarian origin of many medications. Originally a red cross.
    • Rx symbol: Originated from Latin (recipere - to take/receive). Initially a prescription heading; it evolved as a symbol of the recipe or prescription list.
    • Other possible origins: the Eye of Horus (Egyptian).
    • Video of Santa Maria Novella Pharmacy URL: Provided

    Historical Mistake and Action - Thalidomide Tragedy

    • Thalidomide: A drug initially used to treat morning sickness, but linked to birth defects in children.
    • Tragic Consequences: Led to severe malformations in over 10,000 children.
    • Regulatory Enhancements: This tragedy led to stricter drug testing and regulation, to prevent future drug-related birth defects.

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    Description

    Explore the rich history of pharmacy in this quiz, covering significant developments in the profession, key events, and the evolution of roles from apothecaries to modern pharmacists. Understand historical mistakes in pharmacy and their corrections, alongside the symbolic representation used in the field.

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