Pharmacy: Liquid Dosage Forms
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Questions and Answers

What is pharmacology the science of?

  • The study of the brain
  • Deals with drugs and how they affect cells (correct)
  • The study of bones
  • The study of the heart
  • What is the function of drugs?

  • To destroy cells
  • To create new cells
  • To create new cell functions
  • To stimulate or inhibit existing cell functions (correct)
  • What is pharmacokinetics the study of?

  • The pharmaceutical preparation of drugs
  • The mechanism of drug action
  • The rate of absorption, distribution, metabolism and excretion of drug molecules (correct)
  • The pharmacological effects of drugs
  • What is pharmacodynamics?

    <p>What drugs do to the body and how they do it</p> Signup and view all the answers

    What are the five sources of drugs?

    <p>Plants, Animals, Microorganisms, Minerals and Synthetic</p> Signup and view all the answers

    What is the type of dosage form that contains drug substance with or without suitable diluents and prepared either by compression or molding methods?

    <p>Solid dosage form</p> Signup and view all the answers

    What is the purpose of oral tablets?

    <p>To release the medicament within the gastrointestinal tract for absorption into the systemic circulation</p> Signup and view all the answers

    What are the three types of solid dosage forms?

    <p>Tablets, Capsules and Powders</p> Signup and view all the answers

    What is the advantage of tablets in terms of preparation?

    <p>Simplicity and economy of preparation</p> Signup and view all the answers

    What is an advantage of capsules for patients?

    <p>Ease of administration</p> Signup and view all the answers

    What type of powders are packaged individually?

    <p>Divided powders</p> Signup and view all the answers

    What is a characteristic of ointments?

    <p>They are semi-solid and greasy</p> Signup and view all the answers

    What is the purpose of creams?

    <p>To exert emollient or moisturizing effects on the skin</p> Signup and view all the answers

    What is the characteristic of suppositories?

    <p>They are solid medicated preparations designed for insertion into the rectum</p> Signup and view all the answers

    What is similar between pessaries and suppositories?

    <p>They are solid medicated preparations designed for insertion</p> Signup and view all the answers

    What is a characteristic of bulk powders?

    <p>They contain non-potent medicaments</p> Signup and view all the answers

    What is the main advantage of sublingual administration?

    <p>All of the above</p> Signup and view all the answers

    What is a disadvantage of rectal administration?

    <p>Not suitable in case of piles</p> Signup and view all the answers

    What is the main site for intramuscular injection?

    <p>Gluteal muscle</p> Signup and view all the answers

    What is a disadvantage of intravenous injection?

    <p>All of the above</p> Signup and view all the answers

    What is an advantage of subcutaneous administration?

    <p>Slow absorption for sustained effects</p> Signup and view all the answers

    What is a characteristic of sublingual administration?

    <p>Avoids first pass metabolism</p> Signup and view all the answers

    What is an advantage of rectal administration?

    <p>Suitable for drugs affected by digestive enzymes</p> Signup and view all the answers

    What is a characteristic of intradermal injection?

    <p>All of the above</p> Signup and view all the answers

    What is the main purpose of intrathecal injection?

    <p>Treating fungal Meningitis</p> Signup and view all the answers

    What is the advantage of inhalation as a route of administration?

    <p>Rapid onset and elimination</p> Signup and view all the answers

    What is the purpose of intracardiac injection?

    <p>Resuscitation</p> Signup and view all the answers

    What is the route of administration of nitroglycerine patches?

    <p>Transdermal</p> Signup and view all the answers

    What is the purpose of intra-articular injection?

    <p>Treating severe rheumatic pain</p> Signup and view all the answers

    What is the route of administration used to treat allergies and infections in the eye?

    <p>In the eye</p> Signup and view all the answers

    What is a solution in pharmaceutical terms?

    <p>A homogeneous mixture of a solid, liquid or gas in another liquid</p> Signup and view all the answers

    What is the purpose of flavored syrups?

    <p>To mask unpleasant tastes</p> Signup and view all the answers

    What is the characteristic of an emulsion?

    <p>A two-phase system prepared by combining two immiscible liquids</p> Signup and view all the answers

    What is the purpose of nasal solutions?

    <p>To produce a local effect in the nasal passages or to produce a systemic effect in many diseases</p> Signup and view all the answers

    What is the characteristic of a suspension?

    <p>A two-phase system consisting of a finely divided solid dispersion in a liquid</p> Signup and view all the answers

    What is the purpose of mouthwashes?

    <p>To treat infections of the mouth and to maintain oral hygiene</p> Signup and view all the answers

    What is the characteristic of parenteral preparations?

    <p>They are sterile dosage forms containing one or more medicaments and designed for parenteral administration</p> Signup and view all the answers

    What is the characteristic of an injection?

    <p>A sterile solution, suspension or emulsion in a suitable aqueous vehicle</p> Signup and view all the answers

    Study Notes

    General Pharmacology

    • Pharmacology is the science that deals with drugs, their effects on cells, and their mechanisms of action.
    • Drugs are chemical agents that stimulate or inhibit existing cell functions, but do not create new ones.

    Divisions of General Pharmacology

    • Pharmacokinetics: The study of the rate of absorption, distribution, metabolism, and excretion (ADME) of drug molecules.
    • Pharmacodynamics: The study of what drugs do to the body (pharmacological effects) and how they do it (mechanism of drug action).
    • Pharmacotherapeutic process: The process of using drugs to prevent, diagnose, and treat diseases.

    Sources of Drugs

    • Plants: Examples include Belladonna, Atropine, Digitalis, and Ephedrine.
    • Animals: Examples include Pig and bovine Insulin.
    • Microorganisms: Examples include Penicillin and Streptomycin.
    • Minerals: Examples include Iron preparations.
    • Synthetic drugs: Most drugs are synthetic.

    Dosage Forms

    Solid Dosage Forms

    • Tablets: Solid dosage forms containing a drug substance with or without suitable diluents, prepared by compression or molding methods.
    • Capsules: Solid dosage forms where the drug is placed in either a hard or soft gelatin shell.
    • Powders: Divided into bulk powders and divided powders, used for internal use.

    Semi-Solid Dosage Forms

    • Creams: Aqueous creams are non-greasy, used to exert emollient or moisturizing effects on the skin or to deliver drugs for percutaneous absorption.
    • Ointments: Semi-solid, greasy preparations for application to the skin, rectum, or nasal mucosa.
    • Pastes: Used to deliver drugs for topical application.
    • Gels: Used to deliver drugs for topical application.

    Molded Solid Dosage Forms

    • Suppositories: Solid medicated preparations designed for insertion into the rectum.
    • Pessaries: Solid medicated preparations designed for insertion into the vagina.

    Liquid Dosage Forms

    • Solutions: Homogeneous mixtures of a solid, liquid, or gas in another liquid.
      • Syrups: Concentrated aqueous solutions of a sugar, usually sucrose.
      • Elixirs: Sweetened hydro-alcoholic solutions.
      • Tinctures: Alcoholic or hydro-alcoholic solutions containing herbal extracts.
      • Gargles: Aqueous solutions used to prevent or treat throat infections.
      • Mouthwashes: Used for oral hygiene and to treat infections of the mouth.
      • Nasal solutions: Aqueous solutions designed to be administered to the nasal passages in drops or sprays.
    • Suspensions: Two-phase systems consisting of a finely divided solid dispersion in a liquid.
    • Emulsions: Two-phase systems prepared by combining two immiscible liquids.

    Sterile Dosage Forms

    • Parenteral preparations: Sterile dosage forms containing one or more medicaments designed for parenteral administration.
      • Injections: Sterile solutions, suspensions, or emulsions in a suitable aqueous vehicle.
      • Sublingual preparations: Placed under the tongue, e.g., Nitroglycerine, Isoprenaline, Clonidine, Nifedipine, and Methyl-testosterone.
      • Rectal preparations: Suppositories, e.g., for irritant drugs or in children.
      • Intraurethral preparations: Used for local effects.

    Administration Routes

    • (A) Oral administration: The most common route, but may be affected by gastrointestinal enzymes and first-pass metabolism.
    • (B) Parenteral administration:
      • Intadermal injection: Used for sensitivity tests and vaccination.
      • Subcutaneous injection: Used for non-irritant substances, provides slow absorption for sustained drug effects.
      • Intramuscular injection: Used for irritant substances, provides rapid absorption.
      • Intravenous injection: Used for rapid onset and emergency situations.
      • Intra-arterial: Used for experimental purposes.
      • Intracardiac injection: Used for resuscitation.
      • Intrathecal injection: Used for treating fungal meningitis.
      • Intra-articular injection: Used for severe rheumatic pain.
      • Intraperitoneal injection: Used for experimental work.
    • (C) Inhalation: Used for rapid onset and emergency situations, e.g., Nitrous oxide, volatile ether, and liquid aerosol.
    • (D) Transdermal: Used for sustained delivery of drugs, e.g., scopolamine, nicotine patches, and nitroglycerine.
    • (E) In the eye: Used for treating allergies and infections, especially in corneal ulcers.

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    Description

    This quiz covers liquid dosage forms, including solutions, suspensions, and emulsions. It specifically focuses on solutions, syrups, and their characteristics in pharmacy.

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