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Pharmacy Lecture 5: The Nervous System
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Pharmacy Lecture 5: The Nervous System

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Questions and Answers

What type of cells are present in the cerebral cortex?

  • Only nerve endings
  • Only supporting cells
  • Five types of cells including pyramidal cells, stellate cells, cells of Martinotti, fusiform cells, and horizontal cells of Cajal (correct)
  • Only pyramidal cells
  • What is the outer layer of meninges around the brain and spinal cord?

  • Ependymal cells
  • Astrocyte
  • Dura mater (correct)
  • Arachnoid
  • What type of ganglia contain the cell bodies of autonomic nerves?

  • Spinal ganglia
  • Autonomic ganglia (correct)
  • Cranial nerve ganglia
  • Dorsal root ganglia
  • What is the function of dorsal root ganglia?

    <p>To contain the cell bodies of sensory neurons</p> Signup and view all the answers

    Where are nerve receptors mainly distributed in the body?

    <p>Mainly in the skin</p> Signup and view all the answers

    What is the characteristic of free nerve endings?

    <p>They are supplied with afferent nerve endings that are free of investing Schwann cells</p> Signup and view all the answers

    What type of nerve endings are found in the deeper layer of the epidermis and in the papillary layer of the dermis?

    <p>Free nerve endings</p> Signup and view all the answers

    What is the characteristic of encapsulated nerve endings?

    <p>They consist of branched axon enclosed in a discrete connective tissue capsule</p> Signup and view all the answers

    What type of cells are astrocyte, oligodendrocyte, microglia, and ependymal cells?

    <p>Supporting cells</p> Signup and view all the answers

    What is the peripheral nervous system composed of?

    <p>Peripheral nerves, ganglia, and connective tissue investments</p> Signup and view all the answers

    Study Notes

    Nervous System Overview

    • The nervous system consists of two main parts: the Central Nervous System (CNS) and the Peripheral Nervous System (PNS)
    • The CNS includes the brain and spinal cord
    • The nervous system is defined by the presence of a special type of cell called the neuron, also known as a "nerve cell"

    Structure of a Neuron

    • Neurons are the basic functional units of nervous tissue
    • They are highly specialized to transmit nerve impulses
    • Nervous tissue is made up of two types of cells: neurons and neuroglia (glial cells)
    • Neuroglia provide support and protection for neurons and outnumber them

    Histological Components

    • Supporting (non-neuronal) cells: glial cells
      • Astrocytes: star-shaped cells that play an active role in brain function by influencing the activity of neurons
      • Types of astrocytes: Pacinian corpuscles, Meissner's corpuscles, Ruffini corpuscles, and Krause end bulbs

    Components of a Neuron

    • Cell body: the expanded portion of the neuron that contains the nucleus
    • Dendrites: one to many extensions of the cell body that receive input from other neurons or from receptors
    • Axon: a neuron process that projects to and synapses with dendrites or cell bodies of other neurons or with non-neuronal targets

    Types of Neurons

    • Anaxonic neurons: no distinct axon or dendrites; found in the brain and special sense organs
    • Bipolar neurons: one dendrite and one axon; found in special sense organs and relay from receptors to neurons
    • Unipolar neurons: one long axon and dendrites at one end; found in most sensory neurons
    • Multipolar neurons: two or more dendrites and one long axon; found in most CNS neurons

    Functions of Neurons

    • Motor (Efferent): related to innervation of muscle, glands, etc.; activation of these neurons leads to some motor event
    • Sensory (Afferent): related to the transfer of sensory information; e.g., neurons of spinal (dorsal root) ganglia
    • Interneurons: neither motor nor sensory; e.g., neurons responsible for the various spinal reflexes

    Axons

    • Morphologically, axons are divided into two types: myelinated and non-myelinated
    • Myelinated axons: invested with a membranous, lipid sheath; allow for increased speed of conduction along an axon
    • Nodes of Ranvier: breaks in the continuity of the myelin sheath; occur regularly in both the peripheral and central nervous systems

    Neuroglia of the PNS

    • Schwann cells: provide myelination to axons in the PNS and have phagocytotic activity
    • Satellite cells: surround neurons in sensory, sympathetic, and parasympathetic ganglia, helping to regulate the external chemical environment

    The Central Nervous System

    • Principal structures: cerebrum, cerebellum, and spinal cord
    • The cerebral cortex contains five types of cells: pyramidal cells, stellate cells, cells of Martinotti, fusiform cells, and horizontal cells of Cajal

    Meninges

    • Three layers of meninges around the brain and spinal cord: dura mater, arachnoid, and pia mater

    Peripheral Nervous System

    • Consists of peripheral nerves, ganglia, and nerve endings
    • Three types of ganglia: dorsal root ganglia, cranial nerve ganglia, and autonomic ganglia

    Nerve Endings (Receptors)

    • Distributed throughout the body, mainly in the skin
    • Two types of nerve endings: free nerve endings and encapsulated nerve endings

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    Description

    This quiz covers the basics of the nervous system, including its parts, functions, and cellular components. Topics include the central and peripheral nervous systems, the brain, and spinal cord.

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