Pharmacy Compounding Techniques
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Questions and Answers

What is the main purpose of combining an acid and bicarbonate or carbonate in Potion Riviere?

  • To produce CO2 (correct)
  • To increase viscosity
  • To enhance the color
  • To create a sweet flavor
  • What is the volume of water used to dissolve the NaHCO3 in the preparation of Potion Riviere?

  • 30 ml
  • 20 ml (correct)
  • 10 ml
  • 15 ml
  • Which ingredient acts as a sweetening agent in Potion Riviere?

  • Citric acid
  • NaHCO3
  • Syrup of lemon (correct)
  • Water
  • What is a characteristic effect of CO2 produced in effervescent solutions?

    <p>It masks the salty taste</p> Signup and view all the answers

    Why is it recommended to use a slight excess of acid in the preparation of the effervescent solution?

    <p>To improve the taste</p> Signup and view all the answers

    What type of solution is described by the term 'Infusion'?

    <p>A dilute solution of soluble constituents</p> Signup and view all the answers

    What should not be added to the alkaline solution due to the risk of creating a 'dead mixture'?

    <p>Syrup of lemon</p> Signup and view all the answers

    What role do NaHCO3 and citric acid play in Potion Riviere?

    <p>They are inert components that react to produce CO2</p> Signup and view all the answers

    What is the purpose of using boiling water in the preparation of fresh infusions?

    <p>To ensure the quick extraction of active compounds</p> Signup and view all the answers

    Which ingredient in the Black Draught serves as a sweetening agent?

    <p>Liq extract of liquorice</p> Signup and view all the answers

    What is the main characteristic differentiating a decoction from an infusion?

    <p>Decoctions involve boiling and are heat stable</p> Signup and view all the answers

    What is the calculated final volume of liquid after adding the excess water in the preparation of the infusion of Senna?

    <p>42ml</p> Signup and view all the answers

    What is the use of K citrate in the formulations mentioned?

    <p>Alkalinizer</p> Signup and view all the answers

    Why is soaking plant material for 20 minutes essential before boiling in the decoction preparation?

    <p>To improve extraction efficiency</p> Signup and view all the answers

    In the preparation of the infusion of Senna, what is the main role of water?

    <p>As a carrier and extracting solvent</p> Signup and view all the answers

    What is the significance of filtering through wetted cotton during decoction preparation?

    <p>To retain coagulated albuminous matter</p> Signup and view all the answers

    Study Notes

    Effervescent Solution (Potion Riviere)

    • A mixture of a recently prepared salt (from combining an acid and a carbonate/bicarbonate)
    • Produced at the time of dispensing
    • Mixture is saturated with carbon dioxide (CO2)
    • Chemical equation: Acid + Bicarbonate/Carbonate → CO2 + Salt + H2O

    Alkaline and Acid Solutions

    • Prescriptions for both alkaline and acid solutions are provided
    • Ingredients and quantities for each solution are detailed (e.g., NaHCO3, citric acid, simple syrup, syrup of lemon, water)
    • Each solution is measured (e.g., 0.35 g NaHCO3, 2 ml simple syrup)
    • Instructions to mix both solutions directly before use are given

    Calculations (General)

    • F= 2/1
    • Amount of vehicle = 30-4=26 ml (example)

    Procedure (General)

    • Instructions for specific preparations
    • Dissolve ingredients into a vehicle (usually water) in a specific order.
    • Top up to a final volume
    • Pour into separate containers
    • Label containers

    Infusion Senna

    • Uses Senna leaves for laxative use
    • Senna leaves: 5g
    • Boiling water: 100ml (to make 100ml of finished solution)
    • Finished solution volume: 30ml
    • Calculations for F = 0.3, 40% excess water, total volume: 42 ml
    • Procedure details: soak, filter, and don't fill to final volume

    Black Draught

    • Liquid medication intended for oral administration
    • Prescribed in large doses
    • Ingredients and quantities are detailed (e.g., MgSO4, tr Cardomum, liquid extract of liquorice, aromatic spirit NH3, infusion senna)
    • Instructions for preparing the solution are provided

    Decoction of Ammi Visnaga

    • Uses Ammi visnaga for a preparation
    • Ammi visnaga: 5g
    • Cold water: 100 ml
    • Finished solution volume: 30ml
    • Calculation F=30/100=0.3, 40% excess water, total volume: 42 ml
    • Procedure details: crushing plant, soaking, boiling for 10 minutes, filter, adjust to final volume

    Decoction (General)

    • A process for extracting water-soluble, heat-stable ingredients from crude drugs by boiling them in water

    Practical Work (General)

    • Prescriptions and quantities for different solutions are detailed for different practical components (e.g., K citrate, Tr. Hyoscyamin, Dec. Ammi visnaga)
    • Instructions for preparing solutions
    • Calculations for final volumes are provided (e.g., F = 1, Decoction = 30-2=28ml)

    Tools

    • Materials for preparing the different solutions (e.g., watch glass, spatulas, beakers, cylinders, funnel, cotton)
    • Measuring devices provided (e.g., graduated pipettes and droppers).

    Uses (General)

    • A list of specific uses for different ingredients in the various preparations (e.g., laxative, antispasmodic)

    Comparison Between Infusion and Decoction

    • A table comparing the two methods of preparing liquid drugs highlighting their differences

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    Related Documents

    Pharmaceutical Calculations PDF

    Description

    Explore essential techniques for compounding effervescent solutions and alkaline/acids in pharmacy. This quiz covers the chemical reactions, measurement, and procedural steps necessary for preparation. Test your knowledge on the accuracy of ingredient mixing and dosage calculations.

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