17 Questions
What is the primary function of NSF in vesicle fusion?
To break the SNARE complex using ATP energy
Which type of vesicle is involved in constitutive secretion and fuses with the membrane in a non-regulated fashion?
Class 1 vesicles
What is a characteristic feature of chemical synapses?
Synaptic delay of approximately 0.5 ms
What is the purpose of SNAP in vesicle fusion?
To attach NSF to the SNARE complex
What is a characteristic feature of neuromuscular junctions?
Chemical synapse with rapid neurotransmission
What type of connection is characterized by the direct transmission of ions between neurons?
Gap junction
In which part of the presynaptic neuron do synaptic vesicles cluster to release transmitters?
Active zone
What is the process by which vesicles are refilled with transmitter after recycling?
Refilling of the vesicle with transmitter
What is the term for the process by which vesicles release their contents into the synaptic cleft?
Exocytosis
What is the type of synapse that involves the release of neurotransmitters from the presynaptic neuron to the postsynaptic neuron?
Chemical synapse
What is the term for the process by which vesicles are removed from the membrane and recycled for subsequent release?
Vesicle recycling
What is the primary function of receptor-mediated endocytosis in regulating synaptic vesicle release?
To recycle synaptic vesicle membrane after fusion
What is the characteristic feature of microtubules in axons?
They have their plus ends distal from the cell body
What is the primary function of microfilaments in neurons?
To provide structural support to the neuron
Which motor protein is involved in retrograde transport in neurons?
MAP-1C
What is the purpose of fast axonal transport in neurons?
To transport organelles and molecules along the axon
What is the fate of retrograde transport vesicles in neurons?
They fuse with cell body compartments to form mature lysosomes
This quiz covers the morphological basis of neurotransmission, including chemical synapses, electrical synapses, and the process of synaptic transmission. It's designed for 1st semester pharmacy students.
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