Pharmacy 1st Semester: Neurobiology and Synaptic Transmission
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Questions and Answers

What is the primary function of NSF in vesicle fusion?

  • To facilitate the docking of vesicles
  • To regulate the release of neurotransmitters
  • To break the SNARE complex using ATP energy (correct)
  • To form the SNARE complex

    • Which type of vesicle is involved in constitutive secretion and fuses with the membrane in a non-regulated fashion?

  • Class 1 vesicles (correct)
  • Class 2 vesicles
  • Lysosomal vesicles
  • Endosomal vesicles

    • What is a characteristic feature of chemical synapses?

  • Synaptic delay of approximately 0.5 ms (correct)
  • No synaptic fatigue
  • No release of neurotransmitters
  • Direct electrical connection between neurons

    • What is the purpose of SNAP in vesicle fusion?

    <p>To attach NSF to the SNARE complex</p> Signup and view all the answers

    What is a characteristic feature of neuromuscular junctions?

    <p>Chemical synapse with rapid neurotransmission</p> Signup and view all the answers

    What type of connection is characterized by the direct transmission of ions between neurons?

    <p>Gap junction</p> Signup and view all the answers

    In which part of the presynaptic neuron do synaptic vesicles cluster to release transmitters?

    <p>Active zone</p> Signup and view all the answers

    What is the process by which vesicles are refilled with transmitter after recycling?

    <p>Refilling of the vesicle with transmitter</p> Signup and view all the answers

    What is the term for the process by which vesicles release their contents into the synaptic cleft?

    <p>Exocytosis</p> Signup and view all the answers

    What is the type of synapse that involves the release of neurotransmitters from the presynaptic neuron to the postsynaptic neuron?

    <p>Chemical synapse</p> Signup and view all the answers

    What is the term for the process by which vesicles are removed from the membrane and recycled for subsequent release?

    <p>Vesicle recycling</p> Signup and view all the answers

    What is the primary function of receptor-mediated endocytosis in regulating synaptic vesicle release?

    <p>To recycle synaptic vesicle membrane after fusion</p> Signup and view all the answers

    What is the characteristic feature of microtubules in axons?

    <p>They have their plus ends distal from the cell body</p> Signup and view all the answers

    What is the primary function of microfilaments in neurons?

    <p>To provide structural support to the neuron</p> Signup and view all the answers

    Which motor protein is involved in retrograde transport in neurons?

    <p>MAP-1C</p> Signup and view all the answers

    What is the purpose of fast axonal transport in neurons?

    <p>To transport organelles and molecules along the axon</p> Signup and view all the answers

    What is the fate of retrograde transport vesicles in neurons?

    <p>They fuse with cell body compartments to form mature lysosomes</p> Signup and view all the answers

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