10 Questions
What event is considered to mark the beginning of modern pharmacovigilance?
The unjustified claims of safety in pregnancy for thalidomide
What is the significance of thalidomide in the history of drug safety?
It led to the recognition of the need for pharmacovigilance
Which country was particularly affected by thalidomide's teratogenic effects?
Germany
What was the initial cause thought to be for the major increase in birth defects in Germany?
Environmental factors
When was thalidomide finally recognized as a problem and withdrawn from sale?
1961
What was the main problem associated with the use of thalidomide?
It caused birth defects, particularly limb defects known as phocomelia
Who initially made unjustified claims of safety in pregnancy regarding thalidomide?
Pharmaceutical companies
Which country first marketed thalidomide and was particularly affected by the teratogenic effects?
Germany
What caused a major increase in the incidence of phocomelia, a rare congenital abnormality, in Germany?
Environmental factors
What event is considered to mark the beginning of modern pharmacovigilance?
The thalidomide tragedy
Test your knowledge on the origins and history of pharmacovigilance, focusing on the pivotal role of thalidomide in shaping modern drug safety regulations and practices.
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