Pharmacotherapy for Mental Health Lecture 7 Quiz
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Questions and Answers

Which genetic polymorphism is associated with higher sensitivity to stress?

  • CREB
  • Monoamine neurotransmitters
  • BDNF
  • 5-HTPLLR (correct)

According to the given text, what protein promotes the development of neurons and protects them from damage?

  • 5-HTPLLR
  • CREB
  • Monoamine neurotransmitters
  • BDNF (correct)

What type of feeling helps 'prepare' us for potential danger?

  • Emotional
  • Physiological
  • Behavioural
  • Anxiety (correct)

What substance signals DNA to produce BDNF?

<p>CREB (A)</p> Signup and view all the answers

What reduces the levels of BDNF in the brain?

<p>Chronic stress (C)</p> Signup and view all the answers

What type of symptoms lead to the diagnosis of anxiety disorders?

<p>Emotional, behavioural, and physiological (B)</p> Signup and view all the answers

Which neurotransmitter is associated with theories of depression?

<p>Monoamine neurotransmitters (B)</p> Signup and view all the answers

What is the protein that stimulates synaptic plasticity of 5-HT axons?

<p>BDNF (C)</p> Signup and view all the answers

'Unipolar or major depression' does not include which term mentioned in the video?

<p>'Bipolar disorder' (A)</p> Signup and view all the answers

'DSM V' has different classifications for which disorders?

<p>'Anxiety disorders' (A)</p> Signup and view all the answers

Which of the following is a characteristic of depression according to the DSM criteria?

<p>Difficulty concentrating and feelings of guilt (C)</p> Signup and view all the answers

What is the lifetime prevalence of depression, as mentioned in the lecture?

<p>Approximately 6-7% (C)</p> Signup and view all the answers

Which type of depression is characterized by milder symptoms that have been present for a long time?

<p>Persistent Depressive Disorder (D)</p> Signup and view all the answers

According to Ota and Duman (2013) and Wilner et al (2013), what is well known to contribute to depression?

<p>Early life adversity and stress (A)</p> Signup and view all the answers

Which category of drugs is used to treat depression and/or anxiety, as mentioned in the lecture?

<p>SSRIs, tricyclics, MAOIs, benzodiazepines, and 'Z-drugs' (D)</p> Signup and view all the answers

What is schizophrenia characterized by?

<p>Delusions and hallucinations (D)</p> Signup and view all the answers

Depression is more common in men than in women.

<p>False (B)</p> Signup and view all the answers

Chronic stress is not known to contribute to depression.

<p>False (B)</p> Signup and view all the answers

Major Depressive Disorder is characterized by milder symptoms that have been present for a long time.

<p>False (B)</p> Signup and view all the answers

Schizophrenia is primarily treated with SSRIs.

<p>False (B)</p> Signup and view all the answers

Anhedonia refers to an increased interest in pleasurable activities.

<p>False (B)</p> Signup and view all the answers

The lifetime prevalence of depression is approximately 6-7%.

<p>True (A)</p> Signup and view all the answers

Chronic stress increases levels of BDNF in the brain

<p>False (B)</p> Signup and view all the answers

The 5-HTPLLR polymorphism is linked to lower sensitivity to stress

<p>False (B)</p> Signup and view all the answers

Antidepressants raise circulating levels of monoamines, supporting the theory that depression is due to low levels of monoamine neurotransmitters

<p>False (B)</p> Signup and view all the answers

BDNF levels are higher in acute episodes of depression

<p>False (B)</p> Signup and view all the answers

BDNF levels measured by blood sample could predict response to antidepressant drugs

<p>True (A)</p> Signup and view all the answers

Anxiety can only be expressed emotionally and behaviorally, not physiologically

<p>False (B)</p> Signup and view all the answers

Anxiety disorders are only diagnosed when the symptoms seriously impact social function, not occupational function

<p>False (B)</p> Signup and view all the answers

DSM V has only one classification of anxiety disorder

<p>False (B)</p> Signup and view all the answers

Generalized anxiety disorder is the only type of anxiety disorder mentioned in the text

<p>False (B)</p> Signup and view all the answers

Schizophrenia is a type of anxiety disorder mentioned in the text

<p>False (B)</p> Signup and view all the answers

Study Notes

Genetic Polymorphism and Stress

  • The 5-HTTLPR polymorphism is associated with higher sensitivity to stress.

Neuron Development and Protection

  • The protein BDNF (Brain-Derived Neurotrophic Factor) promotes the development of neurons and protects them from damage.

Anxiety and Warning Signals

  • Anxiety helps prepare us for potential danger by sending warning signals.

BDNF Production and Regulation

  • Corticosterone signals DNA to produce BDNF.
  • Chronic stress reduces the levels of BDNF in the brain.

Anxiety Disorders and Diagnosis

  • Anxiety disorders are diagnosed when symptoms lead to significant distress or impairment in social or occupational functioning.
  • DSM V has different classifications for anxiety disorders.

Depression and Neurotransmitters

  • The neurotransmitter serotonin (5-HT) is associated with theories of depression.
  • The protein BDNF stimulates synaptic plasticity of 5-HT axons.

Depression Characteristics and Classification

  • 'Unipolar or major depression' does not include 'bipolar'.
  • Major Depressive Disorder is characterized by at least two weeks of low mood or anhedonia (loss of interest in pleasurable activities).
  • The lifetime prevalence of depression is approximately 15%.
  • Dysthymia is characterized by milder symptoms that have been present for a long time.

Depression Risk Factors and Treatment

  • Chronic stress is a well-known contributor to depression.
  • Antidepressants raise circulating levels of monoamines, supporting the theory that depression is due to low levels of monoamine neurotransmitters.
  • SSRIs (Selective Serotonin Reuptake Inhibitors) are a category of drugs used to treat depression and/or anxiety.

Schizophrenia Characteristics

  • Schizophrenia is primarily characterized by positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., apathy, social withdrawal), and is not primarily treated with SSRIs.

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Test your knowledge on the pharmacotherapy for mental health, focusing on the drugs used to treat depression, anxiety, and schizophrenia. Learn about SSRIs, tricyclics, MAOIs, benzodiazepines, 'Z-drugs', and the three 'generations' of drugs used to treat schizophrenia.

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