Pharmacotherapy for Mental Health Lecture 7 Quiz
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Questions and Answers

Which genetic polymorphism is associated with higher sensitivity to stress?

  • CREB
  • Monoamine neurotransmitters
  • BDNF
  • 5-HTPLLR (correct)
  • According to the given text, what protein promotes the development of neurons and protects them from damage?

  • 5-HTPLLR
  • CREB
  • Monoamine neurotransmitters
  • BDNF (correct)
  • What type of feeling helps 'prepare' us for potential danger?

  • Emotional
  • Physiological
  • Behavioural
  • Anxiety (correct)
  • What substance signals DNA to produce BDNF?

    <p>CREB</p> Signup and view all the answers

    What reduces the levels of BDNF in the brain?

    <p>Chronic stress</p> Signup and view all the answers

    What type of symptoms lead to the diagnosis of anxiety disorders?

    <p>Emotional, behavioural, and physiological</p> Signup and view all the answers

    Which neurotransmitter is associated with theories of depression?

    <p>Monoamine neurotransmitters</p> Signup and view all the answers

    What is the protein that stimulates synaptic plasticity of 5-HT axons?

    <p>BDNF</p> Signup and view all the answers

    'Unipolar or major depression' does not include which term mentioned in the video?

    <p>'Bipolar disorder'</p> Signup and view all the answers

    'DSM V' has different classifications for which disorders?

    <p>'Anxiety disorders'</p> Signup and view all the answers

    Which of the following is a characteristic of depression according to the DSM criteria?

    <p>Difficulty concentrating and feelings of guilt</p> Signup and view all the answers

    What is the lifetime prevalence of depression, as mentioned in the lecture?

    <p>Approximately 6-7%</p> Signup and view all the answers

    Which type of depression is characterized by milder symptoms that have been present for a long time?

    <p>Persistent Depressive Disorder</p> Signup and view all the answers

    According to Ota and Duman (2013) and Wilner et al (2013), what is well known to contribute to depression?

    <p>Early life adversity and stress</p> Signup and view all the answers

    Which category of drugs is used to treat depression and/or anxiety, as mentioned in the lecture?

    <p>SSRIs, tricyclics, MAOIs, benzodiazepines, and 'Z-drugs'</p> Signup and view all the answers

    What is schizophrenia characterized by?

    <p>Delusions and hallucinations</p> Signup and view all the answers

    Depression is more common in men than in women.

    <p>False</p> Signup and view all the answers

    Chronic stress is not known to contribute to depression.

    <p>False</p> Signup and view all the answers

    Major Depressive Disorder is characterized by milder symptoms that have been present for a long time.

    <p>False</p> Signup and view all the answers

    Schizophrenia is primarily treated with SSRIs.

    <p>False</p> Signup and view all the answers

    Anhedonia refers to an increased interest in pleasurable activities.

    <p>False</p> Signup and view all the answers

    The lifetime prevalence of depression is approximately 6-7%.

    <p>True</p> Signup and view all the answers

    Chronic stress increases levels of BDNF in the brain

    <p>False</p> Signup and view all the answers

    The 5-HTPLLR polymorphism is linked to lower sensitivity to stress

    <p>False</p> Signup and view all the answers

    Antidepressants raise circulating levels of monoamines, supporting the theory that depression is due to low levels of monoamine neurotransmitters

    <p>False</p> Signup and view all the answers

    BDNF levels are higher in acute episodes of depression

    <p>False</p> Signup and view all the answers

    BDNF levels measured by blood sample could predict response to antidepressant drugs

    <p>True</p> Signup and view all the answers

    Anxiety can only be expressed emotionally and behaviorally, not physiologically

    <p>False</p> Signup and view all the answers

    Anxiety disorders are only diagnosed when the symptoms seriously impact social function, not occupational function

    <p>False</p> Signup and view all the answers

    DSM V has only one classification of anxiety disorder

    <p>False</p> Signup and view all the answers

    Generalized anxiety disorder is the only type of anxiety disorder mentioned in the text

    <p>False</p> Signup and view all the answers

    Schizophrenia is a type of anxiety disorder mentioned in the text

    <p>False</p> Signup and view all the answers

    Study Notes

    Genetic Polymorphism and Stress

    • The 5-HTTLPR polymorphism is associated with higher sensitivity to stress.

    Neuron Development and Protection

    • The protein BDNF (Brain-Derived Neurotrophic Factor) promotes the development of neurons and protects them from damage.

    Anxiety and Warning Signals

    • Anxiety helps prepare us for potential danger by sending warning signals.

    BDNF Production and Regulation

    • Corticosterone signals DNA to produce BDNF.
    • Chronic stress reduces the levels of BDNF in the brain.

    Anxiety Disorders and Diagnosis

    • Anxiety disorders are diagnosed when symptoms lead to significant distress or impairment in social or occupational functioning.
    • DSM V has different classifications for anxiety disorders.

    Depression and Neurotransmitters

    • The neurotransmitter serotonin (5-HT) is associated with theories of depression.
    • The protein BDNF stimulates synaptic plasticity of 5-HT axons.

    Depression Characteristics and Classification

    • 'Unipolar or major depression' does not include 'bipolar'.
    • Major Depressive Disorder is characterized by at least two weeks of low mood or anhedonia (loss of interest in pleasurable activities).
    • The lifetime prevalence of depression is approximately 15%.
    • Dysthymia is characterized by milder symptoms that have been present for a long time.

    Depression Risk Factors and Treatment

    • Chronic stress is a well-known contributor to depression.
    • Antidepressants raise circulating levels of monoamines, supporting the theory that depression is due to low levels of monoamine neurotransmitters.
    • SSRIs (Selective Serotonin Reuptake Inhibitors) are a category of drugs used to treat depression and/or anxiety.

    Schizophrenia Characteristics

    • Schizophrenia is primarily characterized by positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., apathy, social withdrawal), and is not primarily treated with SSRIs.

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    Description

    Test your knowledge on the pharmacotherapy for mental health, focusing on the drugs used to treat depression, anxiety, and schizophrenia. Learn about SSRIs, tricyclics, MAOIs, benzodiazepines, 'Z-drugs', and the three 'generations' of drugs used to treat schizophrenia.

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