Pharmacology Subject Wise Test

<p>Amiodarone (B)</p> Signup and view all the answers

<p>Adacanumab (A)</p> Signup and view all the answers

<p>Perindopril (B)</p> Signup and view all the answers

<p>Acetazolamide (D)</p> Signup and view all the answers

<p>Levetiracetam (D)</p> Signup and view all the answers

<p>Constant fraction of drug is eliminated per unit time (A)</p> Signup and view all the answers

<p>Tmax (D)</p> Signup and view all the answers

<p>Promethazine (A)</p> Signup and view all the answers

<p>5HT-1B/1D (C)</p> Signup and view all the answers

<p>Naltrexone (A), Methadone (B)</p> Signup and view all the answers

<p>None of the above (D)</p> Signup and view all the answers

<p>Prevention of granulocyte migration (A)</p> Signup and view all the answers

<p>Trospium (A)</p> Signup and view all the answers

<p>5HT3-blocker (D)</p> Signup and view all the answers

<p>Cyclopentolate (A), Homatropine (D)</p> Signup and view all the answers

<p>Morphine (B)</p> Signup and view all the answers

<p>Denosumab (D)</p> Signup and view all the answers

<p>PGF2-Alpha agonist (D)</p> Signup and view all the answers

<p>Km increases and Vmax remains the same (A)</p> Signup and view all the answers

<p>Tamsulosin (B)</p> Signup and view all the answers

<p>Phenylephrine (C)</p> Signup and view all the answers

<p>PCT (A)</p> Signup and view all the answers

<p>Trospium (D)</p> Signup and view all the answers

<p>Urinary retention (D)</p> Signup and view all the answers

<p>It can be administered orally (C)</p> Signup and view all the answers

<p>Ceftriaxone (C)</p> Signup and view all the answers

<p>Cilastatin inhibits an enzyme in the kidney destroying Imipenem (B)</p> Signup and view all the answers

<p>Postural hypotension (A)</p> Signup and view all the answers

<p>Bedaquiline (B)</p> Signup and view all the answers

<p>Gabapentin (D)</p> Signup and view all the answers

<p>Allopurinol (A)</p> Signup and view all the answers

<p>Fexofenadine (A)</p> Signup and view all the answers

<p>Phenytoin (A)</p> Signup and view all the answers

<p>Silodosin (C)</p> Signup and view all the answers

<p>Mannitol (D)</p> Signup and view all the answers

<p>Thalidomide (C)</p> Signup and view all the answers

<p>Chloroquine (C)</p> Signup and view all the answers

<p>Latanoprost (A)</p> Signup and view all the answers

<p>Benzhexol (C)</p> Signup and view all the answers

<p>Dobutamine (D)</p> Signup and view all the answers

<p>Side effects of atropine (D)</p> Signup and view all the answers

<p>Phenobarbitone (D)</p> Signup and view all the answers

Methimazole is a medication used to treat hyperthyroidism, a condition where the thyroid gland produces excessive amounts of hormones.

Sulfonylureas work by inhibiting ATP-sensitive potassium channels, stimulating insulin release from the pancreas.

Acute dystonia is a potentially serious side effect of haloperidol, characterized by involuntary muscle contractions, especially in the face and neck.

Amiodarone is contraindicated in patients with pre-existing interstitial lung disease due to potential adverse effects on the lungs.

Adacanumab is a monoclonal antibody used in the treatment of Alzheimer's disease.

Perindopril, a type of ACE inhibitor, is generally not recommended for use in pregnant women experiencing hypertension, due to potential fetal risks.

Timolol, a beta-blocker, should be avoided in patients with exercise induced asthma and elevated intraocular pressure (IOP), as it can worsen both conditions.

Levetiracetam is often considered the safest anti-epileptic medication for use during pregnancy due to a lower risk of potential birth defects compared to other options.

A constant fraction of the drug is eliminated per unit time, regardless of the drug concentration.

The rate of absorption is represented by the area under the curve (AUC) on a concentration-time graph.

Rivastigmine is not typically available as a transdermal patch, unlike Rotigotine, Scopolamine, and Promethazine.

Sumatriptan acts as an agonist of the 5HT-1B/1D receptors.

Activated partial thromboplastin time (APTT) is used to monitor enoxaparin therapy.

Colchicine prevents granulocyte migration, thus reducing inflammation in acute gout.

Denosumab is not used for the treatment of sickle cell anaemia. Voxelotor, Hydroxyurea and Crizanlizumab are used.

In competitive antagonism, the maximum velocity (Vmax) remains the same, but the Michaelis constant (Km) increases.

Ethionamide is a drug used to treat tuberculosis. It can cause liver damage, a serious side effect.

Bedaquilline is an anti-tuberculosis drug that inhibits ATP synthase, an enzyme essential for energy production in bacteria.

Prazosin, an alpha-blocker used for hypertension, can cause postural hypotension, a sudden drop in blood pressure when standing up.

Ceftriaxone, an antibiotic, can increase the risk of gallstones, especially in patients with pre-existing conditions.

Fexofenadine is a non-sedating antihistamine used for allergies. It is suitable for patients needing to stay alert.

Silodosin is a more selective alpha-blocker used for BPH (benign prostatic hyperplasia), with less likelihood of causing postural hypotension.

Gabapentin is an anticonvulsant frequently prescribed for postherpetic neuralgia, the persistent pain following shingles.

Allopurinol, a medication for gout, can increase the toxicity of azathioprine, a drug used in organ transplantation.

Naltrexone is a medication used for opioid addiction treatment, working by blocking opioid receptors, preventing the euphoric effects and reducing cravings.

The drug of choice for chemotherapy-induced vomiting is a 5HT3-receptor blocker. It prevents serotonin from activating the vomiting center in the brain.

Morphine, commonly used for pain management, can cause biliary colic by constricting the sphincter of Oddi, leading to bile duct blockage.

Tamsulosin is an alpha-blocker that relaxes the smooth muscle in the prostate and bladder, improving urinary flow and reducing urinary retention.

The drug used to treat Hepatitis C acts primarily on the CD (Cytochrome P450) enzymes in the liver, inhibiting viral replication.

Tiotropium, a bronchodilator, is contraindicated in patients with urinary retention because it can worsen difficulty urinating.

Nesiritide, a BNP analogue used for acute decompensated CHF, is not administered orally. It is given intravenously.

Imipenem, a broad-spectrum antibiotic, is co-administered with Cilastatin to inhibit the enzyme (dehydropeptidase-1) in the kidneys that breaks down Imipenem, ensuring its efficacy.

Mannitol is the diuretic of choice for treating cerebral edema, a condition where the brain swells due to excess fluid.

Phocomelia, a birth defect characterized by abnormally short limbs, is caused by the use of thalidomide during pregnancy.

Chloroquine and primaquine are the recommended drugs for treating Plasmodium vivax malaria in pregnant women.

Timolol, a beta blocker used for glaucoma, can trigger acute bronchial asthma in patients.

Benzhexol is used to treat drug-induced Parkinsonism, which is often caused by antipsychotic medication.

Dobutamine is a drug that improves the heart's pumping action in patients experiencing acute heart failure.

Atropine, used to treat organophosphate poisoning, can cause hyperthermia as a side effect.

Sodium bicarbonate is used to treat drug overdoses that cause central nervous system depression, respiratory failure, and hemodynamic instability.

Phenylephrine, unlike Homatropine, Cyclopentolate, and Tropicamide, does not produce both mydriasis (pupil dilation) and cycloplegia (paralysis of the ciliary muscle).

The darkening in the eye experienced by a glaucoma patient is likely caused by a prostaglandin F2-alpha agonist, a medication that increases outflow of aqueous humor to lower intraocular pressure.

Trospium is the preferred medication for managing urinary incontinence in a patient taking Donepezil, a cholinesterase inhibitor often used for Alzheimer's disease.

Erythromycin is a macrolide antibiotic used to treat bacterial infections.

Mydriasis and cycloplegia are caused by drugs that block muscarinic receptors in the eye. These drugs dilate the pupil and paralyze the ciliary muscle, making it difficult to focus on near objects.