Pharmacology Exam questions

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Questions and Answers

Which of the following is not a subfield of pharmacology?

  • Pharmacodynamics
  • Pharmacokinetics
  • Pharmacoengineering (correct)
  • Pharmacotherapy

What is pharmacology?

  • Te study of the interaction of drugs with biological or physiological systems (correct)
  • The process of drug formation
  • The study of pharmaceutical forms
  • The study of drug names

What is bioavailability?

  • The portion of drug that reaches the systemic circulation without undergoing chemical reaction (correct)
  • The dose that produces te desired therapeutic effect
  • The process of mixing active drug with inactive excipients
  • The amount of drug administration within a 24 hour period

According to Paracelsus, what distinguishes a drug from a poison?

<p>The dose (B)</p> Signup and view all the answers

Which of the following is not a type of treatment?

<p>Curative treatment (D)</p> Signup and view all the answers

Which of the following is NOT a desired characteristic of a drug?

<p>Permanent effect (D)</p> Signup and view all the answers

Drugs can be derived from which of the following natural sources?

<p>All of the above (D)</p> Signup and view all the answers

What is the dose that causes death called?

<p>Lethal dose (C)</p> Signup and view all the answers

What is diagnosis?

<p>Identify a disease (A)</p> Signup and view all the answers

What is treatment?

<p>Managing or curing a disease (C)</p> Signup and view all the answers

What pharmaceutical form is described as slowly dissolving in the mouth providing a localized effect?

<p>Pastilles (B)</p> Signup and view all the answers

What are prepared forms of drugs, such as tablets and ampoules, called?

<p>Pharmaceutical forms (C)</p> Signup and view all the answers

What type of tablet is designed to dissolve in the intestines?

<p>Enteric-coated tablet (B)</p> Signup and view all the answers

Which pharmaceutical form involves a special coating to prevent dissolving in the stomach?

<p>Enteric-coated tablet (B)</p> Signup and view all the answers

A tablet that is placed between the cheek and gum is called a...?

<p>Buccal tablet (C)</p> Signup and view all the answers

What do cylindrical gelatin shells that encase solid or liquid drugs form?

<p>Capsule (B)</p> Signup and view all the answers

What are small volume solutions used externally for eyes, ears or nose called?

<p>Drops (A)</p> Signup and view all the answers

What is the primary requirement for a drug to be effective in a specific location?

<p>Minimum effective concentration (MEK) (B)</p> Signup and view all the answers

When administering drugs, what two factors must be carefully determined?

<p>Amounts and application sites (A)</p> Signup and view all the answers

Routes of drug application are primarily divided into which two categories?

<p>Local and systemic (A)</p> Signup and view all the answers

What primarily influences the choice of drug administration route?

<p>Drug and patient factors (B)</p> Signup and view all the answers

What does pharmacodynamics primarily examine?

<p>The effects of drugs on the body (C)</p> Signup and view all the answers

What does pharmacokinetics primarily examine?

<p>The movement of drugs through the body (B)</p> Signup and view all the answers

Which of the following is NOT a main process involved in pharmacokinetics?

<p>Application (D)</p> Signup and view all the answers

What is drug absorption?

<p>The passage of drugs into the bloodstream (C)</p> Signup and view all the answers

Which of the following is not a local application route for a drug?

<p>Transdermal (D)</p> Signup and view all the answers

I.Suspension II. Coated tablet III.Capsule IV.Solution V.Tablet VI.Emulsion Which option correctly lists the order of absorption from most to least?

<p>IV&gt;VI&gt;I&gt;III&gt;V&gt;II (B)</p> Signup and view all the answers

Which transport methods both require a carrier protein?

<p>Facilitated Diffusion and Active transport (A)</p> Signup and view all the answers

Which of the following is NOT one of the four main phases of pharmacokinetics?

<p>Toxicity (D)</p> Signup and view all the answers

''The percentage of an active drug that reaches systemic circulation'' defines which concept?

<p>Bioavailability (A)</p> Signup and view all the answers

In which pharmacokinetic phase does drug elimination occur?

<p>Excretion (C)</p> Signup and view all the answers

Which of the following is NOT a branch of pharmacotherapy?

<p>Homeopathic treatment (D)</p> Signup and view all the answers

In which organ does drug biotransformation mostly occur?

<p>Liver (B)</p> Signup and view all the answers

Which of the following is NOT an enteral drug administraiton route?

<p>Intravenous (D)</p> Signup and view all the answers

Which of the following is NOT a systemic drug administration route?

<p>Epidermal (D)</p> Signup and view all the answers

Which of the following is one of the most important factors affecting drug distribution?

<p>Drug binding to plasma proteins (C)</p> Signup and view all the answers

Which of the following is an advantage of intravenous drug administration?

<p>Bypasses the gastrointestinal tract (B)</p> Signup and view all the answers

Which of the following is NOT a factor affecting drug distribution in the body?

<p>Drug color (D)</p> Signup and view all the answers

Which of the following drug forms administered via inhalation?

<p>Nebulizer (C)</p> Signup and view all the answers

Which pharmacological term refers to ''the ratio of a drug's therapeutic dose to its toxic dose''?

<p>Therapeutic index (C)</p> Signup and view all the answers

Which of the following is NOT a mechanism of drug elimination?

<p>Storage in nerve cells (D)</p> Signup and view all the answers

What is the main focus of pharmacodynamics?

<p>What the drug does to the body (B)</p> Signup and view all the answers

At which stage does the drug enter circulation in the body?

<p>Absorption (C)</p> Signup and view all the answers

Which of the following is NOT a pharmacokinetic process?

<p>Receptor interaction (D)</p> Signup and view all the answers

What type of transport allows a drug to cross the cell membrane using energy?

<p>Active transport (C)</p> Signup and view all the answers

Which pharmaceutical form has the fastest absorption?

<p>Solution (D)</p> Signup and view all the answers

Weak acidic drugs are better absorbed in which pH environment?

<p>Acidic (C)</p> Signup and view all the answers

Where is an orally administered drug mostly absorbed?

<p>Small intestine (D)</p> Signup and view all the answers

Which of the following does NOT affect drug distribution?

<p>Absorption rate (D)</p> Signup and view all the answers

How do antagonist drugs work?

<p>Block the receptor (B)</p> Signup and view all the answers

Which of the following is an example of an example of an agonist drug?

<p>Salbutamol (B)</p> Signup and view all the answers

Which of the following is true about passive diffusion?

<p>Moves from high to low concentration (C)</p> Signup and view all the answers

What differentiates facilitated diffusion from passive diffision?

<p>Requires a carrier protein (C)</p> Signup and view all the answers

Which factor increases the absorption rate of a drug?

<p>Being lipophilic (B)</p> Signup and view all the answers

Which organ is primarily responsible for drug elimination?

<p>Kidneys (B)</p> Signup and view all the answers

What is the main goal of metabolism?

<p>To make the drug water-soluble for excretion (C)</p> Signup and view all the answers

What is the metabolic process that activates a drug?

<p>Pro-drug activation (B)</p> Signup and view all the answers

What does the half-life of a drug represent?

<p>The time for plasma concentration to decrease by half (C)</p> Signup and view all the answers

In which tissue do lipophilic drugs accumulate the most?

<p>Fat tissue (C)</p> Signup and view all the answers

Which statement is true for a drug administered intravenously?

<p>Directly enters the systemic circulation (B)</p> Signup and view all the answers

Flashcards

What is pharmacology?

The study of the interaction of drugs with biological systems.

What is bioavailability?

The amount of drug that reaches the bloodstream without being changed.

Drug vs. Poison (Paracelsus)

The dose.

What is treatment?

Managing or curing a disease.

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What is diagnosis?

Identify a disease

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What is lethal dose?

The dose that causes death

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Pharmaceutical forms

Prepared forms of drugs, like tablets or ampules

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What are pastilles?

Dissolves slowly in the mouth for a localized effect.

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Enteric-coated tablet

Designed to dissolve in the intestines.

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Buccal tablet

Placed between cheek and gum

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Bioavailability

The percentage of an administered drug that reaches systemic circulation.

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Pharmacokinetics

The study of what the body does to the drug.

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Excretion

The phase of pharmacokinetics where the drug is eliminated from the body.

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Absorption

The process by which a drug moves from the site of administration to the bloodstream.

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Metabolism

The process of chemically changing a drug in the body for the purpose of elimination.

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Distribution

The process by which a drug is dispersed throughout the fluids and tissues in the body.

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Study Notes

Algorithmic Complexity

  • Measures the time and space resources required for an algorithm to run.
  • Time complexity refers to how long an algorithm takes to complete.
  • Space complexity refers to how much memory an algorithm requires.

Importance of Algorithmic Complexity

  • Allows comparison of the efficiency of different algorithms.
  • Helps in thinking about the scalability of algorithms as input size increases.

Measurement

  • Big O notation expresses algorithmic complexity.

Big O Notation Explained

  • Describes the limiting behavior of a function as its argument approaches a specific value or infinity.
  • Classifies algorithms based on how their runtime or space needs increase with input size.

Common Complexities (Best to Worst)

  • Constant: $O(1)$ execution time remains constant regardless of input size.
  • Logarithmic: $O(log n)$ execution time increases logarithmically with input size.
  • Linear: $O(n)$ execution time is directly proportional to input size.
  • Linearithmic: $O(n log n)$ execution time increases linearly and logarithmically with input size.
  • Quadratic: $O(n^2)$ execution time is proportional to the square of the input size.
  • Exponential: $O(2^n)$ execution time doubles with each addition to the input data.
  • Factorial: $O(n!)$ execution time is proportional to the factorial of the input size and avoided whenever possible.
  • $n$ represents the input size.

Visual Representation of Complexities

  • The x-axis represents the "Elements" or input size.
  • The y-axis represents the "Operations" or required time/space resources.
  • Various curves represent different complexities:
    • $O(1)$ is a horizontal line, indicating constant time.
    • $O(log n)$ grows very slowly.
    • $O(n)$ is a straight line, indicating linear growth.
    • $O(n log n)$ grows faster than $O(n)$ but slower than $O(n^2)$.
    • $O(n^2)$ grows quadratically.
    • $O(2^n)$ grows exponentially.
    • $O(n!)$ grows the fastest among the listed complexities.

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