10 Questions
How does andexanet alfa work?
It acts as a decoy molecule that binds to factor Xa inhibitors, thereby reversing their anticoagulant effects.
What is andexanet alfa indicated for?
Reversal of anticoagulant effects of factor Xa inhibitors such as apixaban and rivaroxaban in cases of life-threatening or uncontrolled bleeding.
Why is monitoring patients important after administering reversal agents?
To ensure their safety and well-being.
What is a potential adverse effect of reversal agents?
Rebound effects, allergic reactions, and cardiovascular effects.
What are some safety considerations for administering reversal agents?
Hypersensitivity or allergy to the reversal agent, pre-existing medical conditions, drug interactions, and pregnancy or breastfeeding status.
Andexanet alfa is administered orally.
False
Andexanet alfa reverses the anticoagulant effects of warfarin.
False
Rebound effects can occur after the effects of andexanet alfa wear off.
True
Andexanet alfa can cause allergic reactions manifesting as hives, rash, or swelling.
True
Andexanet alfa is safe to administer to pregnant women.
False
Test your knowledge of reversal agents, substances used to counteract the effects of other drugs, and their roles in medical emergencies. Learn about the importance of rapid neutralization of medication effects and the benefits of reversal agents in pharmacology.
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