Pharmacology: Reversal Agents and Their Uses
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Questions and Answers

How does andexanet alfa work?

It acts as a decoy molecule that binds to factor Xa inhibitors, thereby reversing their anticoagulant effects.

What is andexanet alfa indicated for?

Reversal of anticoagulant effects of factor Xa inhibitors such as apixaban and rivaroxaban in cases of life-threatening or uncontrolled bleeding.

Why is monitoring patients important after administering reversal agents?

To ensure their safety and well-being.

What is a potential adverse effect of reversal agents?

<p>Rebound effects, allergic reactions, and cardiovascular effects.</p> Signup and view all the answers

What are some safety considerations for administering reversal agents?

<p>Hypersensitivity or allergy to the reversal agent, pre-existing medical conditions, drug interactions, and pregnancy or breastfeeding status.</p> Signup and view all the answers

Andexanet alfa is administered orally.

<p>False</p> Signup and view all the answers

Andexanet alfa reverses the anticoagulant effects of warfarin.

<p>False</p> Signup and view all the answers

Rebound effects can occur after the effects of andexanet alfa wear off.

<p>True</p> Signup and view all the answers

Andexanet alfa can cause allergic reactions manifesting as hives, rash, or swelling.

<p>True</p> Signup and view all the answers

Andexanet alfa is safe to administer to pregnant women.

<p>False</p> Signup and view all the answers

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