Pharmacology: Respiratory Infections Part 1 Quiz

Play an AI-generated podcast conversation about this lesson

What is the mechanism of action of Levofloxacin in treating bronchitis?

Has a macrolide mechanism of action

Inhibits DNA gyrase and type IV topoisomerase (correct)

Inhibits cell wall synthesis

Prevents inactivation of IMP by renal dehydropeptidase

Which antibiotic is included in preparation to prevent inactivation of IMP by renal dehydropeptidase?

Penicillin G

Azithromycin

Cilastatin (correct)

Levofloxacin

What are the adverse effects associated with Piperacillin + Tazobactam in treating bronchitis?

GI distress, hypersensitivity (correct)

Tendonitis, phototoxicity

Hypersensitivity, cross-sensitivity with penicillins

Nephrotoxicity, ototoxicity

Which antibiotic induces uncoordinated peristalsis by binding to receptors for the gastric hormone, motilin?

Erythromycin Signup and view all the answers

Which antibiotic commonly causes phototoxicity and discoloration of teeth as adverse effects in bronchitis treatment?

Levofloxacin Signup and view all the answers

Which antibiotic inhibits DNA gyrase and topoisomerase IV in bacterial cells?

Ciprofloxacin Signup and view all the answers

What is the mechanism of action of Erythromycin?

Inhibition of protein synthesis Signup and view all the answers

Which antibiotic is a narrow-spectrum penicillin that inhibits cell wall synthesis in Group A Streptococcus?

Amoxicillin Signup and view all the answers

What is the main function of Tazobactam in the combination drug Piperacillin + Tazobactam?

Acts as a β-Lactamase inhibitor Signup and view all the answers

Which antibiotic is a carbapenem and exhibits broad-spectrum activity against Gram-negative bacteria?

Imipenem Signup and view all the answers

What is the primary target of Gentamicin in bacterial cells?

30S ribosomal subunit Signup and view all the answers

What is the first-line antibiotic treatment for an outpatient with community-acquired pneumonia (CAP) who has not taken any antimicrobials in the past 3 months?

Fluoroquinolone Signup and view all the answers

Which antibiotic would be most effective against Mycoplasma pneumoniae due to its mechanism of action at the 30S ribosomal subunit?

Azithromycin Signup and view all the answers

In the case of severe community-acquired pneumonia (CAP) in an inpatient, what is a common antibiotic combination recommended for treatment?

Ceftriaxone + Macrolide Signup and view all the answers

Which antibiotic is effective against Haemophilus influenzae due to its inhibition of cell wall synthesis?

Amoxicillin + Clavulanate Signup and view all the answers

What is the mechanism of action of Imipenem that makes it particularly effective against Klebsiella pneumoniae?

Broad spectrum and resistant to many β-Lactamases Signup and view all the answers

Which pharmacologic agent is most appropriate for treating Moraxella catarrhalis based on its characteristics as a Gram-negative diplococcus?