Pharmacology: Respiratory Infections Part 1 Quiz
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Questions and Answers

What is the mechanism of action of Levofloxacin in treating bronchitis?

  • Has a macrolide mechanism of action
  • Inhibits DNA gyrase and type IV topoisomerase (correct)
  • Inhibits cell wall synthesis
  • Prevents inactivation of IMP by renal dehydropeptidase
  • Which antibiotic is included in preparation to prevent inactivation of IMP by renal dehydropeptidase?

  • Penicillin G
  • Azithromycin
  • Cilastatin (correct)
  • Levofloxacin
  • What are the adverse effects associated with Piperacillin + Tazobactam in treating bronchitis?

  • GI distress, hypersensitivity (correct)
  • Tendonitis, phototoxicity
  • Hypersensitivity, cross-sensitivity with penicillins
  • Nephrotoxicity, ototoxicity
  • Which antibiotic induces uncoordinated peristalsis by binding to receptors for the gastric hormone, motilin?

    <p>Erythromycin</p> Signup and view all the answers

    Which antibiotic commonly causes phototoxicity and discoloration of teeth as adverse effects in bronchitis treatment?

    <p>Levofloxacin</p> Signup and view all the answers

    Which antibiotic inhibits DNA gyrase and topoisomerase IV in bacterial cells?

    <p>Ciprofloxacin</p> Signup and view all the answers

    What is the mechanism of action of Erythromycin?

    <p>Inhibition of protein synthesis</p> Signup and view all the answers

    Which antibiotic is a narrow-spectrum penicillin that inhibits cell wall synthesis in Group A Streptococcus?

    <p>Amoxicillin</p> Signup and view all the answers

    What is the main function of Tazobactam in the combination drug Piperacillin + Tazobactam?

    <p>Acts as a β-Lactamase inhibitor</p> Signup and view all the answers

    Which antibiotic is a carbapenem and exhibits broad-spectrum activity against Gram-negative bacteria?

    <p>Imipenem</p> Signup and view all the answers

    What is the primary target of Gentamicin in bacterial cells?

    <p>30S ribosomal subunit</p> Signup and view all the answers

    What is the first-line antibiotic treatment for an outpatient with community-acquired pneumonia (CAP) who has not taken any antimicrobials in the past 3 months?

    <p>Fluoroquinolone</p> Signup and view all the answers

    Which antibiotic would be most effective against Mycoplasma pneumoniae due to its mechanism of action at the 30S ribosomal subunit?

    <p>Azithromycin</p> Signup and view all the answers

    In the case of severe community-acquired pneumonia (CAP) in an inpatient, what is a common antibiotic combination recommended for treatment?

    <p>Ceftriaxone + Macrolide</p> Signup and view all the answers

    Which antibiotic is effective against Haemophilus influenzae due to its inhibition of cell wall synthesis?

    <p>Amoxicillin + Clavulanate</p> Signup and view all the answers

    What is the mechanism of action of Imipenem that makes it particularly effective against Klebsiella pneumoniae?

    <p>Broad spectrum and resistant to many β-Lactamases</p> Signup and view all the answers

    Which pharmacologic agent is most appropriate for treating Moraxella catarrhalis based on its characteristics as a Gram-negative diplococcus?

    <p>Amoxicillin + Clavulanate</p> Signup and view all the answers

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