Pharmacology: Respiratory Infections Part 1 Quiz

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Questions and Answers

What is the mechanism of action of Levofloxacin in treating bronchitis?

  • Has a macrolide mechanism of action
  • Inhibits DNA gyrase and type IV topoisomerase (correct)
  • Inhibits cell wall synthesis
  • Prevents inactivation of IMP by renal dehydropeptidase

Which antibiotic is included in preparation to prevent inactivation of IMP by renal dehydropeptidase?

  • Penicillin G
  • Azithromycin
  • Cilastatin (correct)
  • Levofloxacin

What are the adverse effects associated with Piperacillin + Tazobactam in treating bronchitis?

  • GI distress, hypersensitivity (correct)
  • Tendonitis, phototoxicity
  • Hypersensitivity, cross-sensitivity with penicillins
  • Nephrotoxicity, ototoxicity

Which antibiotic induces uncoordinated peristalsis by binding to receptors for the gastric hormone, motilin?

<p>Erythromycin (A)</p> Signup and view all the answers

Which antibiotic commonly causes phototoxicity and discoloration of teeth as adverse effects in bronchitis treatment?

<p>Levofloxacin (D)</p> Signup and view all the answers

Which antibiotic inhibits DNA gyrase and topoisomerase IV in bacterial cells?

<p>Ciprofloxacin (C)</p> Signup and view all the answers

What is the mechanism of action of Erythromycin?

<p>Inhibition of protein synthesis (B)</p> Signup and view all the answers

Which antibiotic is a narrow-spectrum penicillin that inhibits cell wall synthesis in Group A Streptococcus?

<p>Amoxicillin (A)</p> Signup and view all the answers

What is the main function of Tazobactam in the combination drug Piperacillin + Tazobactam?

<p>Acts as a β-Lactamase inhibitor (A)</p> Signup and view all the answers

Which antibiotic is a carbapenem and exhibits broad-spectrum activity against Gram-negative bacteria?

<p>Imipenem (C)</p> Signup and view all the answers

What is the primary target of Gentamicin in bacterial cells?

<p>30S ribosomal subunit (C)</p> Signup and view all the answers

What is the first-line antibiotic treatment for an outpatient with community-acquired pneumonia (CAP) who has not taken any antimicrobials in the past 3 months?

<p>Fluoroquinolone (A)</p> Signup and view all the answers

Which antibiotic would be most effective against Mycoplasma pneumoniae due to its mechanism of action at the 30S ribosomal subunit?

<p>Azithromycin (C)</p> Signup and view all the answers

In the case of severe community-acquired pneumonia (CAP) in an inpatient, what is a common antibiotic combination recommended for treatment?

<p>Ceftriaxone + Macrolide (C)</p> Signup and view all the answers

Which antibiotic is effective against Haemophilus influenzae due to its inhibition of cell wall synthesis?

<p>Amoxicillin + Clavulanate (C)</p> Signup and view all the answers

What is the mechanism of action of Imipenem that makes it particularly effective against Klebsiella pneumoniae?

<p>Broad spectrum and resistant to many β-Lactamases (B)</p> Signup and view all the answers

Which pharmacologic agent is most appropriate for treating Moraxella catarrhalis based on its characteristics as a Gram-negative diplococcus?

<p>Amoxicillin + Clavulanate (A)</p> Signup and view all the answers

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