12 Questions
What is the primary effect of a sedative on motor or mental function?
It exerts a calming effect with no significant impact
What is the typical duration of a complete sleep cycle?
90 to 100 minutes
What is the primary mechanism of action of diazepam?
Binding to and modulating the GABA type A receptor
What is the effect of diazepam on REM sleep?
It decreases REM sleep
What is the characteristic of diazepam that allows for its quick entry into the CNS?
Its very high lipid solubility
What is the clinical application of diazepam in anaesthesia?
As an anaesthetic agent
What is the primary mechanism of metabolism of diazepam?
Phase I oxidation
What is the effect of discontinuing diazepam treatment?
Rebound increase in REM sleep
Which of the following is a characteristic of isoflurane?
Less soluble in blood and tissues
What is the primary mechanism of action of propofol?
Potentiation of GABA activity on GABA-Type A channels
What is the primary use of flumazenil?
Treatment of benzodiazepine overdose
What is the onset of action of propofol?
Within 40 seconds of injection
Test your knowledge of sedative-hypnotics and general anaesthetics, including their definitions, effects, and functions. This quiz covers the basics of pharmacology and is ideal for students of pharmacy and medicine.
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