Pharmacology 4: General Anesthetics

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30 Questions

What is the main characteristic of general anesthesia?

Loss of consciousness, analgesia, amnesia, and skeletal muscle relaxation

Why are multiple drugs combined in balanced anesthesia?

To take advantage of individual drug properties and reduce adverse actions

What is the main purpose of anxiolytics in preanesthetic medications?

To provide sedation and amnesia

What is the main purpose of anti-cholinergics in preanesthetic medications?

To reduce bronchial and salivary secretion

What is the purpose of vasopressors in preanesthetic medications?

To prevent bradycardia and hypotension

What is the purpose of opioid analgesics in preanesthetic medications?

To provide analgesia

What is the purpose of administering morphine, fentanyl, or alfentanil 1½ hours before anesthesia?

To facilitate low potency anesthetics such as nitrous oxide

How do anesthetic agents affect GABA-A-receptor chloride channels?

They increase CL- conductance and hyperpolarize

Which of the following anesthetics is known to inhibit excitatory glutamate-gated ion channels?

Nitrous oxide

What is a unique feature of alfentanil compared to fentanyl?

Faster recovery

What is a contraindication for the use of thiopental?

Porphyria

What is a characteristic of etomidate compared to thiopental?

Larger margin between anesthetic and respiratory depressant doses

Which induction agent is preferable in cases of risk of circulatory failure?

Propofol

What is a characteristic of Ketamine anaesthesia?

Cardiovascular stimulation

Which agent is known to cause unpleasant dreams and diplopia as a side effect?

Ketamine

What is a benefit of using Propofol for induction?

Rapid and pleasant induction

Which benzodiazepine is most commonly employed as an anaesthetic adjunct?

Midazolam

What is a contraindication for the use of Ketamine?

Stroke

What is the primary purpose of using an i.v. analgesic agent in anesthesia?

To provide supplementary analgesia

Which of the following inhalation anesthetics is known to have a potent uterine relaxant effect?

Methoxyflurane

What is a potential disadvantage of using Enflurane?

Nephrotoxicity

Which of the following is a contraindication for Methoxyflurane?

Epilepsy

Which inhalation anesthetic is safe for use in children and asthmatics?

Methoxyflurane

What is a potential complication of using Methoxyflurane?

Nephrotoxicity

What is a disadvantage of isoflurane?

Pungent and respiratory irritant

What type of local anesthetics does cocaine belong to?

Esters

What is the purpose of adding vasoconstrictors to local anesthetics?

To increase the duration of action

Why should vasoconstrictors not be added to local anesthetics for hands and feet?

To avoid tissue damage and gangrene

What is the purpose of adding sodium bicarbonate to local anesthetics?

To increase the lipid solubility of the anesthetic

What is the purpose of surface anesthesia?

To treat itching caused by insect bites or irritant conditions

This quiz covers the topic of general anesthesia in pharmacology, including its characteristics, balanced anesthesia, and the use of different drugs and medications.

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